; Published 18 February 2018 Academic Editor: Sari Pennings Copyright © 2018 Halima Albalushi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits ... hES cell cultures. Conflicts of Interest The authors declare that they have no conflicts of interest. Authors’ Contributions Halima Albalushi, Jan-Bernd Stukenborg, and Outi Hovatta conceived and
; Published 18 February 2018 Academic Editor: Sari Pennings Copyright © 2018 Halima Albalushi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits ... hES cell cultures. Conflicts of Interest The authors declare that they have no conflicts of interest. Authors’ Contributions Halima Albalushi, Jan-Bernd Stukenborg, and Outi Hovatta conceived and
; Published 18 February 2018 Academic Editor: Sari Pennings Copyright © 2018 Halima Albalushi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits ... hES cell cultures. Conflicts of Interest The authors declare that they have no conflicts of interest. Authors’ Contributions Halima Albalushi, Jan-Bernd Stukenborg, and Outi Hovatta conceived and
somatic gonadal cells, when used as a matrix for hES cell cultures. Conflicts of Interest The authors declare that they have no conflicts of interest. Authors’ Contributions Halima Albalushi, Jan-Bernd ... Stukenborg, and Outi Hovatta conceived and designed the experiments. Halima Albalushi, Magdalena Kurek, Luise Landreh, and Kristín Rós Kjartansdóttir performed the experiments. Kristín Rós Kjartansdóttir and
Finding robust culture conditions for in vitro maturation (IVM) of male germ cells is still a challenge. Recently, a testis organ culture method, using Knockout Serum Replacement (KSR), was suggested as a promising approach. However, the efficiency of that model is still not optimal. Hence, we have tried to establish the culture conditions in two laboratories, and to improve the...
The mechanisms underlying human germ cell development are largely unknown, partly due to the scarcity of primordial germ cells and the inaccessibility of the human germline to genetic analysis. Human embryonic stem cells can differentiate to germ cells in vitro and can be genetically modified to study the genetic requirements for germ cell development. Here, we studied NANOS3 and...