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303 papers found.
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Mechanisms of action of Coxiella burnetii effectors inferred from host-pathogen protein interactions

, Seesandra V. Rajagopala. Data curation: Anders Wallqvist, Hao Wang, Nela Zavaljevski, Vesna MemiÏsević, Keehwan Formal analysis: Anders Wallqvist, Hao Wang, Nela Zavaljevski, Vesna MemisÏević, Rembert

Semaphorin 7A as a potential immune regulator and promising therapeutic target in rheumatoid arthritis

Background Semaphorin 7A (Sema7A) is expressed by several different classes of lymphoid and myeloid cells and is a potent immunomodulator. We examined the role of Sema7A in modulating cellular immune responses and to provide experimental data validating the therapeutic potential of Sema7A in rheumatoid arthritis (RA). Methods Soluble Sema7A (sSema7A) levels in the serum and ...

Broadband Perfect Absorber with Monolayer MoS2 and Hexagonal Titanium Nitride Nano-disk Array

A broadband metamaterial absorber (MA) composed of hexagonal-arranged single-sized titanium nitride (TiN) nano-disk array and monolayer molybdenum disulfide (MoS2) is studied using finite-difference time-domain (FDTD) simulations. The structure of TiN nano-disk array/dielectric silica (SiO2)/aluminum (Al) is adopted in our design. By optimizing the dimension parameters of the ...

Oxygen environment and islet size are the primary limiting factors of isolated pancreatic islet survival

Komatsu, Colin Cook, Chia-Hao Wang, Leonard Medrano. Formal analysis: Hirotake Komatsu, Colin Cook, Chia-Hao Wang. Funding acquisition: Yoko Mullen. Investigation: Hirotake Komatsu, Colin Cook, Leonard ... Medrano. Methodology: Hirotake Komatsu, Colin Cook, Chia-Hao Wang. Project administration: Henry Lin. Resources: Henry Lin. Supervision: Fouad Kandeel, Yu-Chong Tai, Yoko Mullen. Visualization

Interactive Tooth Separation from Dental Model Using Segmentation Field

Tooth segmentation on dental model is an essential step of computer-aided-design systems for orthodontic virtual treatment planning. However, fast and accurate identifying cutting boundary to separate teeth from dental model still remains a challenge, due to various geometrical shapes of teeth, complex tooth arrangements, different dental model qualities, and varying degrees of ...

Incidence and severity of acute mountain sickness and associated symptoms in children trekking on Xue Mountain, Taiwan

and in subjects with a higher body mass index (BMI) (p < 0.05). Memorial Hospital did not save the research data, future interested individuals may contact the corresponding author, Shih-Hao Wang () for ... Day 2. Author Contributions Conceptualization: Fei-Ying Cheng, Shih-Hao Wang. Data curation: Fei-Ying Cheng, Mei-Jy Jeng, Yin-Chou Lin, Shih-Hao Wang, Shih-Hao Wu, Wen-Cheng Li, Kuo-Feng Huang, Te

Testing the effect of the Himalayan mountains as a physical barrier to gene flow in Hippophae tibetana Schlect. (Elaeagnaceae)

Hippophae tibetana is a small, dioecious wind-pollinated shrub endemic to the Tibetan-Qinghai Plateau. It is one of the shrubs that occur at very high elevations (5250 m a.s.l.). The Himalayan mountains provides a significant geographical barrier to the Qinghai-Tibetan Plateau, dividing the Himalayan area into two regions with Nepal to the south and Tibet to the north. There is no ...

FSW of aluminum AA5754 to steel DX54 with innovative overlap joint

An innovative overlap joint concept was tested to evaluate the quality improvement of welds between aluminum alloy AA5754-H22 (2 mm) and steel DX54 (1.5 mm). The innovation is a wave-shaped interface produced on the steel being directly processed by the tip of the probe, generating localized heat, extensive chemically active surfaces, and additional mechanical interlocking. Welds ...

Fulranumab in patients with interstitial cystitis/bladder pain syndrome: observations from a randomized, double-blind, placebo-controlled study

approved the final version of the article, including the authorship list. Competing interests Dr. Hao Wang was an employee of Janssen Research & Development, LLC, in Raritan/Titusville, NJ, USA during the

FSW of aluminum AA5754 to steel DX54 with innovative overlap joint

An innovative overlap joint concept was tested to evaluate the quality improvement of welds between aluminum alloy AA5754-H22 (2 mm) and steel DX54 (1.5 mm). The innovation is a wave-shaped interface produced on the steel being directly processed by the tip of the probe, generating localized heat, extensive chemically active surfaces, and additional mechanical interlocking. Welds ...

Research Progress in Improving the Cycling Stability of High-Voltage LiNi0.5Mn1.5O4 Cathode in Lithium-Ion Battery

High-voltage lithium-ion batteries (HVLIBs) are considered as promising devices of energy storage for electric vehicle, hybrid electric vehicle, and other high-power equipment. HVLIBs require their own platform voltages to be higher than 4.5 V on charge. Lithium nickel manganese spinel LiNi0.5Mn1.5O4 (LNMO) cathode is the most promising candidate among the 5 V cathode materials for ...

Ocean Wave Simulation Based on Wind Field

Ocean wave simulation has a wide range of applications in movies, video games and training systems. Wind force is the main energy resource for generating ocean waves, which are the result of the interaction between wind and the ocean surface. While numerous methods to handle simulating oceans and other fluid phenomena have undergone rapid development during the past years in the ...

muBLASTP: database-indexed protein sequence search on multicore CPUs

://github.com/vtsynergy/muBLASTP/tree/master/query_data. Authors’ contributions Jing Zhang and Sanchit Misra developed muBLASTP. Jing Zhang, Hao Wang, and Wu-chun Feng wrote the manuscript. All authors read and

The value of [11C]-acetate PET and [18F]-FDG PET in hepatocellular carcinoma before and after treatment with transarterial chemoembolization and bevacizumab

Purpose This prospective study was to investigate the value of [11C]-acetate PET and [18F]-FDG PET in the evaluation of hepatocellular carcinoma (HCC) before and after treatment with transarterial chemoembolization (TACE) and vascular endothelial growth factor (VEGF) antibody (bevacizumab). Methods Twenty-two patients (three women, 19 men; 62 ± 8 years) with HCC verified by ...

Hybrid Pareto artificial bee colony algorithm for multi-objective single machine group scheduling problem with sequence-dependent setup times and learning effects

Zailin Guan Ullah Saif 0 Fei Zhang Hao Wang 0 Department of Industrial Engineering, University of Engineering and Technology , Taxila , Pakistan Group scheduling is significant for efficient and cost

Rolling Resistance and Mechanical Properties of Grinded Copper Surfaces Using Molecular Dynamics Simulation

Mechanical properties of copper (Cu) film under grinding process were accomplished by molecular dynamics simulation. A numerical calculation was carried out to understand the distributions of atomic and slip vector inside the Cu films. In this study, the roller rotation velocity, temperature, and roller rotation direction change are investigated to clarify their effect on the ...

Mesenchymal stroma cells in peritoneal dialysis effluents from patients

mesenchymal stroma cells - & Hao Wang Mesenchymal stroma cells (MSCs), historically termed as mesenchymal stem cells, are multipotent fibroblast-like, adult stroma cells that were first isolated from the

Whole Genome Mapping with Feature Sets from High-Throughput Sequencing Data

A good physical map is essential to guide sequence assembly in de novo whole genome sequencing, especially when sequences are produced by high-throughput sequencing such as next-generation-sequencing (NGS) technology. We here present a novel method, Feature sets-based Genome Mapping (FGM). With FGM, physical map and draft whole genome sequences can be generated, anchored and ...

Chronic activation of PPARα with fenofibrate reduces autophagic proteins in the liver of mice independent of FGF21

Autophagy is a catabolic mechanism to degrade cellular components to maintain cellular energy levels during starvation, a condition where PPARα may be activated. Here we report a reduced autophagic capacity in the liver following chronic activation of PPARα with fenofibrate (FB) in mice. Chronic administration of the PPARα agonist FB substantially reduced the levels of multiple ...