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In vitro analysis of the proliferative capacity and cytotoxic effects of ex vivo induced natural killer cells, cytokine-induced killer cells, and gamma-delta T cells

Niu 0 Haofan Jin 0 Min Li Jianting Xu Dongsheng Xu Jifan Hu Hua He Wei Li Jiuwei Cui 0 Equal contributors Cancer Center, the First Hospital of Jilin University , 71 Xinmin Street, Changchun 130021

Cellular immunotherapy as maintenance therapy prolongs the survival of the patients with small cell lung cancer

Background Small cell lung cancer (SCLC) relapses rapidly after the initial response to chemotherapy and shows drug-resistance. This study was to investigate the efficacy and safety of cellular immunotherapy (CIT) with autologous natural killer (NK), γδT, and cytokine-induced killer (CIK) cells as maintenance therapy for SCLC patients. Methods A pilot prospective cohort study was ...