Advanced search    

Search: authors:"He Huang"

111 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

On the main signless Laplacian eigenvalues of a graph

DENG† AND HE HUANG† AMS subject classifications. 05C50. 1. Introduction. Let M be a square matrix of order n. An eigenvalue λ of M is said to be a main eigenvalue if the eigenspace ε(λ) of λ is not ... the Program for Science and Technology Innovative Research Team in Higher Educational Institution of Hunan Province. 382 Hanyuan Deng and He Huang the main signless Laplacian eigenvalues of G. The

Prediction and characterization of a novel hemocyanin-derived antimicrobial peptide from shrimp Litopenaeus vannamei

broad-spectrum activity against different organisms including Gram-positive and Gram-negative Shen Yang and He Huang contributed equally. bacteria (Zhu et al. 2014; Dolashka et al. 2011; Zhuang et al

Novel immunotherapies for adult patients with B-lineage acute lymphoblastic leukemia

The past decade witnessed the rapid development of adult B-lineage acute lymphoblastic leukemia (ALL) treatment. Beyond the development of chemotherapy regimens, immunotherapy is starting a new era with unprecedented complete remission (CR) rate. Targeting B-lineage-specific surface markers such as CD19, CD20, CD22, or CD52, immunotherapy has been demonstrating promising clinical...

Notch3 inhibits epithelial–mesenchymal transition in breast cancer via a novel mechanism, upregulation of GATA-3 expression

, ChinaHao-Yu Lin, Yuan-Ke Liang, Xiao-Wei Dou, Chun-Fa Chen, Xiao-Long Wei, De Zeng, Jing-Wen Bai, Yu-Xian Guo, Fang-Fang Lin, Wen-He Huang, Yao-Chen Li & Guo-Jun ZhangChangJiang Scholar’s Laboratory, The ... Guo in:Nature Research journals • PubMed • Google Scholar Search for Fang-Fang Lin in:Nature Research journals • PubMed • Google Scholar Search for Wen-He Huang in:Nature Research journals • PubMed

Expression patterns of microRNA-329 and its clinical performance in diagnosis and prognosis of breast cancer

Expression patterns of microRNA-329 and its clinical performance in diagnosis and prognosis of breast cancer Pihong Li,* Jianda Dong,* Xiang Zhou, Weijian Sun, He Huang, Tong Chen, Bing Ye, Zhiqiang

mTOR inhibition improves the immunomodulatory properties of human bone marrow mesenchymal stem cells by inducing COX-2 and PGE2

BackgroundBone marrow mesenchymal stem cells (MSCs) are promising candidates for the treatment of various inflammatory disorders due to their profound immunomodulatory properties. However, the immunosuppressive capacity of MSCs needs activation by an inflammatory microenvironment, which may negatively impact the therapeutic effect because of increased immunogenicity. Here we...

Using Optimal Control to Disambiguate the Effect of Depression on Sensorimotor, Motivational and Goal-Setting Functions

Differentiating the ability from the motivation to act is of central importance to psychiatric disorders in general and depression in particular. However, it has been difficult to develop quantitative approaches to relate depression to poor motor performance in goal-directed tasks. Here, we use an inverse optimal control approach to provide a computational framework that can be...

Age-associated microbiome shows the giant panda lives on hemicelluloses, not on cellulose

, Sichuan, ChinaWenping Zhang, Rong Hou, Liang Zhang, Junjin Xie, Chengdong Wang, He Huang, Hairui Wang, Fujun Shen & Zhihe ZhangNovogene Bioinformatics Institute, Beijing, 100083, PR ChinaWenbin Liu, Huaibo ... • Google Scholar Search for He Huang in:Nature Research journals • PubMed • Google Scholar Search for Hairui Wang in:Nature Research journals • PubMed • Google Scholar Search for Fujun Shen in:Nature

SpyTag/SpyCatcher Cyclization Enhances the Thermostability of Firefly Luciferase

SpyTag can spontaneously form a covalent isopeptide bond with its protein partner SpyCatcher. Firefly luciferase from Photinus pyralis was cyclized in vivo by fusing SpyCatcher at the N terminus and SpyTag at the C terminus. Circular LUC was more thermostable and alkali-tolerant than the wild type, without compromising the specific activity. Structural analysis indicated that the...

On signaling pathways: hematopoietic stem cell specification from hemogenic endothelium

Hematopoietic stem cells (HSCs) are specified and generated during the embryonic development and have remarkable potential to replenish the full set of blood cell lineages. Researchers have long been interested in clarifying the molecular events involved in HSC specification. Many studies have reported the development of methods for generating functional hematopoietic cells from...

Increased histone deacetylase 6 expression serves as a favorable prognostic factor for diffuse large B-cell lymphoma

He Huang,1 Wen-Jian Guo,1 Hai-Yan Lin,1 Rong-Xin Yao1 1Department of Haematology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, 2Science and Technology of

Investigating the Influence of MoS2 Nanosheets on E. coli from Metabolomics Level

Molybdenum disulfide, a type of two-dimensional layered material with unique properties, has been widely used in many fields. However, an exact understanding of its toxicity remains elusive, let alone its effects on the environmental microbial community. In this study, we utilized metabolomics technology to explore the effects of different concentrations of molybdenum disulfide...

Enhanced neuroinflammation mediated by DNA methylation of the glucocorticoid receptor triggers cognitive dysfunction after sevoflurane anesthesia in adult rats subjected to maternal separation during the neonatal period

Background Mounting evidence indicates that children who experience abuse and neglect are prone to chronic diseases and premature mortality later in life. One mechanistic hypothesis for this phenomenon is that early life adversity alters the expression or functioning of the glucocorticoid receptor (GR) throughout the course of life and thereby increases sensitivity to...

Label-Free 3D Ag Nanoflower-Based Electrochemical Immunosensor for the Detection of Escherichia coli O157:H7 Pathogens

It is highly desirable to develop a rapid and simple method to detect pathogens. Combining nanomaterials with electrochemical techniques is an efficient way for pathogen detection. Herein, a novel 3D Ag nanoflower was prepared via a biomineralization method by using bovine serum albumin (BSA) as a template. It was adopted as a sensing interface to construct an electrochemical...

pH-sensitive Au–BSA–DOX–FA nanocomposites for combined CT imaging and targeted drug delivery

pH-sensitive Au-BSA-DOX-FA nanocomposites for combined CT imaging and targeted drug delivery He Huang,1 Da-Peng Yang,2 Minghuan Liu,2 Xiangsheng Wang,1 Zhiyong Zhang,1 Guangdong Zhou,1 Wei Liu,1

Investigation of Timing to Switch Control Mode in Powered Knee Prostheses during Task Transitions

Current powered prosthetic legs require switching control modes according to the task the user is performing (e.g. level-ground walking, stair climbing, walking on slopes, etc.). To allow prosthesis users safely and seamlessly transition between tasks, it is critical to determine when to switch the prosthesis control mode during task transitions. Our previous study defined...

A real-time, practical sensor fault-tolerant module for robust EMG pattern recognition

Background Unreliability of surface EMG recordings over time is a challenge for applying the EMG pattern recognition (PR)-controlled prostheses in clinical practice. Our previous study proposed a sensor fault-tolerant module (SFTM) by utilizing redundant information in multiple EMG signals. The SFTM consists of multiple sensor fault detectors and a self-recovery mechanism that...

The Influence of Depression on Cognitive Control: Disambiguating Approach and Avoidance Tendencies

Dysfunctions of approach and avoidance motivation play an important role in depression, which in turn may affect cognitive control, i.e., the ability to regulate thoughts and action to achieve internal goals. We use a novel experimental paradigm, i.e. a computer simulated driving-task, to study the impact of depression on cognitive control by measuring approach and avoidance...

Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling

Wang, Bin Kong, Peng Zhong, Liang Xiong, Dajun Quan, Qi Li, Guangji Wang & He Huang AuthorsSearch for Xiaojv Xiong in:Nature Research journals • PubMed • Google ScholarSearch for Yu Liu in:Nature ... • Google ScholarSearch for Guangji Wang in:Nature Research journals • PubMed • Google ScholarSearch for He Huang in:Nature Research journals • PubMed • Google Scholar Contributions X.X. and Y.L. conceived