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Identification of natural compounds targeting Annexin A2 with an anti-cancer effect

polyacrylamide gel electrophoresis; STAT3, signal transducer and activator of transcription 3 COMPLIANCE WITH ETHICS GUIDELINES Yu-Shi Wang, He Li, Yang Li, Hongyan Zhu and Ying-Hua Jin declare they have no

Identification and immobilization of a novel cold-adapted esterase, and its potential for bioremediation of pyrethroid-contaminated vegetables

Pyrethroids are potentially harmful to living organisms and ecosystems. Thus, concerns have been raised about pyrethroid residues and their persistence in agricultural products. To date, although several pyrethroid-hydrolyzing enzymes have been cloned, very few reports are available on pyrethroid-hydrolyzing enzymes with cold adaptation, high hydrolytic activity and good...

The gut microbiota in young and middle-aged rats showed different responses to chicken protein in their diet

Background Meat protein in the diet has been shown to be beneficial for the growth of Lactobacillus in the caecum of growing rats; however, it is unknown whether gut microbiota in middle-aged animals have the same responses to meat protein diets. This study compared the composition of the gut microbiota between young and middle-aged rats after being fed 17.7% chicken protein diet...

A case of intravascular large B cell lymphoma presenting as nodular goiter

Intravascular large B-cell lymphoma (IVLBCL) is a subtype of diffuse large B-cell lymphoma (DLBCL) that is rare and highly aggressive and that may progressively involve many organs. CNS (central nervous system), BM (bone marrow) and skin are the most common systems involved. To date, only 2 cases of IVLBCL involving the thyroid have been reported. Here, we report a case of IVLBCL...

Population Genetic Analyses of the Fungal Pathogen Colletotrichum fructicola on Tea-Oil Trees in China

The filamentous fungus Colletotrichum fructicola is found in all five continents and is capable of causing severe diseases in a number of economically important plants such as avocado, fig, cocoa, pear, and tea-oil trees. However, almost nothing is known about its patterns of genetic variation and epidemiology on any of its host plant species. Here we analyzed 167 isolates of C...

Zincobotryogen, ZnFe3+(SO4)2(OH)⋅7H2O: validation as a mineral species and new data

Zincobotryogen occurs in the oxidation zone of the Xitieshan lead-zinc deposit, Qinghai, China. The mineral is associated with jarosite, copiapite, zincocopiapite, and quartz. The mineral forms prismatic crystals, 0.05 to 2 mm in size. It is optically positive (2Vcalc = 54.1°), with Z ‖ b and X ∧ c = 10°. The elongation is negative. The refractive indices are n α = 1.542(5), n...

Distribution and associations of intraocular pressure in 7- and 12-year-old Chinese children: The Anyang Childhood Eye Study

Conceptualization: Shuning Li, Shi-Ming Li, Xiao-lei Wang, Luo-Ru Liu, He Li, Siyan Zhan, Ningli Wang. 7 / 10 Data curation: Shi-Ming Li, Xiao-lei Wang, Meng-Tian Kang, Shi-Fei Wei, An-Ran Ran. Formal analysis ... : Shuning Li, Xiao-lei Wang, Siyan Zhan, Ravi Thomas. Funding acquisition: Luo-Ru Liu, Ningli Wang. Investigation: Shi-Ming Li, Meng-Tian Kang, Luo-Ru Liu, He Li, Shi-Fei Wei, An-Ran Ran. Methodology: Shi

De novo transcriptome sequencing and analysis of male, pseudo-male and female yellow perch, Perca flavescens

Transcriptome sequencing could facilitate discovery of sex-biased genes, biological pathways and molecular markers, which could help clarify the molecular mechanism of sex determination and sexual dimorphism, and assist with selective breeding in aquaculture. Yellow perch has unique gonad system and sexual dimorphism and is an alternative model to study mechanism of sex...

TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence

R. Pinto, Ruping Chen, Lihui Wang, He Li and Jun-Ping Liu declare that they have no conflict of interest. This article does not contain any studies with human or animal subjects performed by any of

Schisandra polysaccharide inhibits hepatic lipid accumulation by downregulating expression of SREBPs in NAFLD mice

the final manuscript. Author information Jian-Guang Chen, PhD and Chun-Mei Wang, PhD, are Professors; Wen-Yue Zhuang, PhD, Jing-Hui Sun, PhD and He Li, PhD are Associate Professors; Rong-Shuang Yuan

Time- and stress-dependent model for predicting moisture retention capacity of high-food-waste-content municipal solid waste: based on experimental evidence

Moisture retention capacity (MRC) is a key parameter for the prediction of leachate production of a municipal solid waste (MSW) pile. In this paper, five sets of laboratory tests were conducted in compression cells to characterize the variation of MRC with degradation time and overburden stress. Set A was conducted on the fresh high-food-waste-content (HFWC)-MSW under different...

Telocytes in the Spleen

Telocytes, a novel type of interstitial cells with very long and thin prolongations, have been identified in many organs in mammals. At present, the ultrastructural, immunocytochemical and electrophysiological properties of telocytes in multiple organs have been understood. However, telocytes in spleen, especially their roles in spleen have not been reported. The aim of this...

Development and application of an efficient gas extraction model for low-rank high-gas coal beds

To promote gas extraction in low-rank high-gas coal beds, the pore structure characteristics of the coal and their effect on gas desorption were studied. The results show that micropores are relatively rare in low-rank coal; mesopores are usually semi-open and inkpot-shaped whereas macropores are usually slit-shaped. Gas desorption is relatively easy at high-pressure stages...

Intake of Meat Proteins Substantially Increased the Relative Abundance of Genus Lactobacillus in Rat Feces

Diet has been shown to have a critical influence on gut bacteria and host health, and high levels of red meat in diet have been shown to increase colonic DNA damage and thus be harmful to gut health. However, previous studies focused more on the effects of meat than of meat proteins. In order to investigate whether intake of meat proteins affects the composition and metabolic...

Concerted Evolution of Duplicate Control Regions in the Mitochondria of Species of the Flatfish Family Bothidae (Teleostei: Pleuronectiformes)

Mitogenomes of flatfishes (Pleuronectiformes) exhibit the greatest diversity of gene rear-rangements in teleostean fishes. Duplicate control regions (CRs) have been found in the mito-genomes of two flatfishes, Samariscus latus (Samaridae) and Laeops lanceolata (Bothidae), which is rare in teleosts. It has been reported that duplicate CRs have evolved in a concerted fashion in...

Redshift drift exploration for interacting dark energy

By detecting redshift drift in the spectra of the Lyman-\(\alpha \) forest of distant quasars, the Sandage–Loeb (SL) test directly measures the expansion of the universe, covering the “redshift desert” of \(2 \lesssim z \lesssim 5\). Thus this method is definitely an important supplement to the other geometric measurements and will play a crucial role in cosmological constraints...

Transcript Quantification by RNA-Seq Reveals Differentially Expressed Genes in the Red and Yellow Fruits of Fragaria vesca

Fragaria vesca (2n = 2x = 14), the woodland strawberry, is a perennial herbaceous plant with a small sequenced genome (240 Mb). It is commonly used as a genetic model plant for the Fragaria genus and the Rosaceae family. Fruit skin color is one of the most important traits for both the commercial and esthetic value of strawberry. Anthocyanins are the most prominent pigments in...

Effects of Nitrogen Addition on Nitrogen Resorption in Temperate Shrublands in Northern China

Nutrient resorption from senescing leaves is a key mechanism of nutrient conservation for plants. The nutrient resorption efficiency is highly dependent on leaf nutrient status, species identity and soil nutrient availability. Nitrogen is a limiting nutrient in most ecosystems, it is widely reported that nitrogen resorption efficiency (NRE) was highly dependent on the soil...

Cosmological constraints on neutrinos after BICEP2

Since the B-mode polarization of the cosmic microwave background (CMB) was detected by the BICEP2 experiment and an unexpectedly large tensor-to-scalar ratio, \(r=0.20^{+0.07}_{-0.05}\), was found, the base standard cosmology should at least be extended to the 7-parameter \(\Lambda \)CDM+\(r\) model. In this paper, we consider the extensions to this base \(\Lambda \)CDM+\(r...