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Decreased activity of RCAN1.4 is a potential risk factor for congenital heart disease in a Han Chinese population

Technology of Shanghai Municipality (13JC1407600) to Hongyan Wang. Liangping Cheng, Peiqiang Li, He Wang, Xueyan Yang, Huiming Zhou, Wufan Tao, Jie Tian and Hongyan Wang declare that they have no conflict of

Effects of increased levels of atmospheric CO2 and high temperatures on rice growth and quality

analysis: Shuo Liu. Investigation: Song-he Wang. Methodology: Shuo Liu. Resources: Shuo Liu, Yun-fan Wan. Writing ± original draft: Shuo Liu. Data curation: Shuo Liu, Song-he Wang, Xiang-yang Xiong

Optimal economic operation of isolated community microgrid incorporating temperature controlling devices

With the increasing connection of controllable devices to isolated community microgrid, an economic operation model of isolated community microgrid based on the temperature regulation characteristics of temperature controlling devices composed of wind turbine, micro-gas turbine, energy storage battery and heat pump is proposed. With full consideration of various economic costs...

ADAR1 overexpression is associated with cervical cancer progression and angiogenesis

Background This study aimed to assess the role of RNA-dependent adenosine deaminase (ADAR1) in cervical squamous cell carcinoma occurrence and progression. Methods ADAR1 expression levels in stage IA and stage IIA cervical squamous cell carcinoma (group A), cervical intraepithelial neoplasia (CIN) specimens (group B), as well as normal and inflamed cervical tissue samples (group...

Clear cell carcinoma arising in previous episiotomy scar: a case report and review of the literature

Background Malignant transformation of endometriosis associated with episiotomy scar is a rare event, especially histological type of clear cell adenocarcinoma. There are only three clear cell carcinoma in episiotomy scar reported, no standard treatment established. Case presentation A 36-year-old woman presented with a two-month history of painless but puritic perineal lump...

The Therapeutic Response of Gastrointestinal Stromal Tumors to Imatinib Treatment Assessed by Intravoxel Incoherent Motion Diffusion-Weighted Magnetic Resonance Imaging with Histopathological Correlation

, 3 and 7 after treatment. Competing Interests: The co-author He Wang is an employee of GE Healthcare. His contribution to this paper included protocol setup and data analyses. We did not receive

Wind speed model based on kernel density estimation and its application in reliability assessment of generating systems

. degree in electrical engineering from Chongqing University, Chongqing, China, in 2014 . His research interests include power system planning and reliability evaluation. He WANG is currently a postgraduate

Functional characterization of an invertase inhibitor gene involved in sucrose metabolism in tomato fruit

YANG 0 Zhi-he WANG 0 0 (Key Laboratory of Protected Horticulture, Ministry of Education, College of Horticulture, Shenyang Agricultural University , Shenyang 110866 , China) 1 Project supported by the ... posttranslational level. Compliance with ethics guidelines Ning ZHANG, Jing JIANG, Yan-li YANG, and Zhi-he WANG declare that they have no conflict of interest. This article does not contain any studies with human

Psychometric properties of the Chinese version of the Obsessive Beliefs Questionnaire-44 (OBQ-44)

Background The Obsessive Beliefs Questionnaire-44 (OBQ-44) is originally developed by the Obsessive Compulsive Cognitions Working Group and has been translated into several languages. This paper is aimed to investigate the psychometric properties of the Chinese version of the Obsessive Beliefs Questionnaire-44 (OBQ-44) in both clinical and non-clinical samples. Methods Five...

Identification and Molecular Characterization of the Homogentisate Pathway Responsible for Pyomelanin Production, the Major Melanin Constituents in Aeromonas media WS

The pigmentation of many Aeromonas species has been thought to be due to the production of a L-DOPA (L-3,4-dihydroxyphenylalanine) based melanin. However, in this study we found that although L-DOPA synthesis occurs in the high-melanin-yielding Aeromonas media strain WS, it plays a minor, if any, role in pigmentation. Instead, the pigmentation of A. media strain WS is due to the...

Development of fluconazole resistance in a series of Candida parapsilosis isolates from a persistent candidemia patient with prolonged antifungal therapy

Background Candida parapsilosis was the most common species causing candidemia in the 2010 China Hospital Invasive Fungal Surveillance Net (CHIF-NET) database. Compared to Candida albicans, the description of azole resistance and mechanisms in C. parapsilosis is very limited. We report a patient with C. parapsilosis candidemia over several months, due to a probable intravascular...

Sequencer-Based Capillary Gel Electrophoresis (SCGE) Targeting the rDNA Internal Transcribed Spacer (ITS) Regions for Accurate Identification of Clinically Important Yeast Species

Accurate species identification of Candida, Cryptococcus, Trichosporon and other yeast pathogens is important for clinical management. In the present study, we developed and evaluated a yeast species identification scheme by determining the rDNA internal transcribed spacer (ITS) region length types (LTs) using a sequencer-based capillary gel electrophoresis (SCGE) approach. A...

Accumulation of invariant NKT cells with increased IFN-γ production in persistent high-risk HPV-infected high-grade cervical intraepithelial neoplasia

detection of HPV DNA. He Wang participated in the design of the study and performed the statistical analysis. SL conceived of the study, participated in its design and coordination and helped to draft the

Follow-up of breast papillary lesion on core needle biopsy: experience in African-American population

Background The optimal course of clinical follow-up after a diagnosis of breast papillary lesion on a core needle biopsy (CNB) remains elusive. In particular, no reports in literature have addressed this question in African-American population. We describe our experience with breast papillary lesions in a primarily African-American population. Methods A search of our database for...

Inhibition of nuclear factor-kappa B enhances the tumor growth of ovarian cancer cell line derived from a low-grade papillary serous carcinoma in p53-independent pathway

Background NF-kB can function as an oncogene or tumor suppressor depending on cancer types. The role of NF-kB in low-grade serous ovarian cancer, however, has never been tested. We sought to elucidate the function of NF-kB in the low-grade serous ovarian cancer. Methods The ovarian cancer cell line, HOC-7, derived from a low-grade papillary serous carcinoma. Introduction of a...

Family functioning, marital quality and social support in Chinese patients with epilepsy

Background The purpose of this study was to examine family functioning, marital quality, social support, and anxiety and depression in Chinese patients with Epilepsy (PWE) in comparison with healthy people. Methods This case–control study included 42 PWE and 42 healthy controls. Participants completed the Zung’s self-rating depression scale, the Zung’s self-rating anxiety scale...

Effects of mineralocorticoid receptor antagonists in patients with preserved ejection fraction: a meta-analysis of randomized clinical trials

Background Mineralocorticoid receptor antagonists (MRAs) have been shown to be effective in patients with heart failure or myocardial infarction complicated by a reduced ejection fraction. However, the role of MRAs in patients with preserved ejection fraction (PEF) remains to be clarified. We aimed to summarize the evidence for the efficacy of MRAs in patients with either heart...

Power measurement system of ECRH on HL-2A

Electron Cyclotron Resonance Heating (ECRH) is one of the main auxiliary heating systems for HL-2A tokamak. The ECRH system with total output power 5MW has been equipped on HL-2A which include 6 sets of 0.5MW/1.0s at a frequency of 68GHz and 2 sets of 1MW/3s at a frequency of 140GHz. The power is one of important parameters in ECRH system. In this paper, the method for measuring...

Evaluation of Multiparametric Magnetic Resonance Imaging in Detection and Prediction of Prostate Cancer

Background Although European Society of Urogenital Radiology proposed the potential of multiparametric magnetic resonance imaging (MP-MRI) as a tool in the diagnostic pathway for prostate cancer (PCa) and published a unified scoring system named Prostate Imaging Reporting and Data System (PI-RADS version 1), these still need to be validated by real-life studies. Objective To...

Prostate cancer identification: quantitative analysis of T2-weighted MR images based on a back propagation artificial neural network model

Computer-aided diagnosis (CAD) systems have been proposed to assist radiologists in making diagnostic decisions by providing helpful information. As one of the most important sequences in prostate magnetic resonance imaging (MRI), image features from T2-weighted images (T2WI) were extracted and evaluated for the diagnostic performances by using CAD. We extracted 12 quantitative...