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Chronic pain and fatigue in adults with congenital unilateral upper limb deficiency in Norway. A cross-sectional study

and professionals in the Norwegian limb deficiency centers for their valuable help and participation. Author Contributions Conceptualization: Heidi Johansen, Liv Øinñs Andersen, Svend Rand-Hendriksen ... , Kristin Østlie. Data curation: Heidi Johansen, Liv Øinñs Andersen, Kristin Østlie. Formal analysis: Heidi Johansen, Trine Bathen, Kristin Østlie. Investigation: Heidi Johansen, Liv Øinñs Andersen

Imaging Surrogates of Disease Activity in Neuromyelitis Optica Allow Distinction from Multiple Sclerosis

Group for Neuromyelitis optica and by NIHR Oxford Biomedical Research Centre. Heidi Johansen-Berg is funded by Neuromyelitis optica is a rare severe relapsing inflammatory central nervous system disorder ... Software Library (FSL). Jonathan Brooks has no relevant conflicts of interest. Heidi Johansen-Berg receives royalties from Elsevier for edited volume Diffusion MRI. Jacqueline Palace has received support

Normalisation of brain connectivity through compensatory behaviour, despite congenital hand absence

Previously we showed, using task-evoked fMRI, that compensatory intact hand usage after amputation facilitates remapping of limb representations in the cortical territory of the missing hand (Makin et al., 2013a). Here we show that compensatory arm usage in individuals born without a hand (one-handers) reflects functional connectivity of spontaneous brain activity in the cortical ...

Health-related quality of life for children with rare diagnoses, their parents’ satisfaction with life and the association between the two

Purpose To examine children’s health-related quality of life and parents’ satisfaction with life and explore the association between the two in families where a child has a rare disorder. Methods We used a cross-sectional study design. A questionnaire was sent to parents of 439 school children (6–18 years) with congenital rare disorders. Children’s health-related quality of life ...

Imaging the relationship between structure, function and behaviour in the human brain

Heidi Johansen-Berg 0 0 H. Johansen-Berg (&) Oxford Centre for Functional MRI of the Brain, University of Oxford , Oxford OX3 9DU, UK - Neuroscience has its roots in the study of brain anatomy

Deprivation-related and use-dependent plasticity go hand in hand

Arm-amputation involves two powerful drivers for brain plasticity—sensory deprivation and altered use. However, research has largely focused on sensory deprivation and maladaptive change. Here we show that adaptive patterns of limb usage after amputation drive cortical plasticity. We report that individuals with congenital or acquired limb-absence vary in whether they ...

Tools of the trade: psychophysiological interactions and functional connectivity

Psychophysiological interactions (PPIs) analysis is a method for investigating task-specific changes in the relationship between activity in different brain areas, using functional magnetic resonance imaging (fMRI) data. Specifically, PPI analyses identify voxels in which activity is more related to activity in a seed region of interest (seed ROI) in a given psychological context, ...

Local GABA concentration is related to network-level resting functional connectivity

Anatomically plausible networks of functionally inter-connected regions have been reliably demonstrated at rest, although the neurochemical basis of these ‘resting state networks’ is not well understood. In this study, we combined magnetic resonance spectroscopy (MRS) and resting state fMRI and demonstrated an inverse relationship between levels of the inhibitory neurotransmitter ...

Distinct and Overlapping Functional Zones in the Cerebellum Defined by Resting State Functional Connectivity

The cerebellum processes information from functionally diverse regions of the cerebral cortex. Cerebellar input and output nuclei have connections with prefrontal, parietal, and sensory cortex as well as motor and premotor cortex. However, the topography of the connections between the cerebellar and cerebral cortices remains largely unmapped, as it is relatively unamenable to ...

Health status of adults with Short Stature: A comparison with the normal population and one well-known chronic disease (Rheumatoid Arthritis)

Background To examine the subjective health status of adults with short stature (ShSt) and compare with the general population (GP) and one well-known chronic disease, rheumatoid artritis (RA). In addition, to explore the association between age, gender, height, educational level and different aspects of health status of adults with short stature. Methods A questionnaire was mailed ...

Functional–Anatomical Validation and Individual Variation of Diffusion Tractography-based Segmentation of the Human Thalamus

anonymous reviewer for useful suggestions for improving the manuscript. Address correspondence to Dr Heidi Johansen-Berg, Centre for Functional Magnetic Resonance Imaging of the Brain, John Radcliffe

The Evolution of Prefrontal Inputs to the Cortico-pontine System: Diffusion Imaging Evidence from Macaque Monkeys and Humans

The cortico-ponto-cerebellar system is one of the largest projection systems in the primate brain, but in the human brain the nature of the information processing in this system remains elusive. Determining the areas of the cerebral cortex which contribute projections to this system will allow us to better understand information processing within it. Information from the cerebral ...