To convince policy-makers or funders of health care of the value of orthopaedic interventions, we need to consider value for money (cost-effectiveness), as well as clinical effectiveness. This article provides an introduction to health economics to set the scene for papers on the use of allografts in the knee.
PurposeOsteochondral allografts (OCA) consist of a layer of hyaline cartilage and a layer of underlying bone. They are used to repair combined defects of articular cartilage and bone. Such defects often occur in people far too young to have knee arthroplasty, for whom the main alternative to OCA is conservative symptomatic care, which will not prevent development of...
PurposeTo review the relative cost-effectiveness of allografts and autografts in reconstruction of the posterior cruciate ligament.MethodsSystematic review and cost-effectiveness analysis.ResultsThe available evidence does not show any significant difference in clinical effectiveness between autografts and allografts. Given that, only a cost analysis is provided, which shows that...
To assess the clinical and cost-effectiveness of allografts versus autografts in the reconstruction of anterior cruciate ligaments. Systematic review of comparative clinical effectiveness and cost-effectiveness analysis. Both autograft and allograft reconstruction are highly effective. Recent studies show little difference in failure rates between autografts and allografts (about...
PurposeTo assess the clinical effectiveness and cost-effectiveness of meniscal allograft transplantation (MAT) after meniscal injury and subsequent meniscectomy.MethodsSystematic review of clinical effectiveness and cost-effectiveness analysis.ResultsThere is considerable evidence from observational studies, of improvement in symptoms after meniscal allograft transplantation, but...
Warwick Evidence, Warwick Medical School, University of Warwick , Gibbet Hill Road, Coventry CV4 7AL , UK 2 & Hema Mistry 3 The Royal Bournemouth Hospital NHS Foundation Trust , Castle Lane East ... the HTA programme website (https:// www.journalslibrary.nihr.ac.uk/programmes/hta/161011/#/) for further project information. Conflict of interest Hema Mistry, Chidozie Nduka, Martin Connock, Jill
Objective Multiplex gastrointestinal pathogen panel (GPP) tests simultaneously identify bacterial, viral and parasitic pathogens from the stool samples of patients with suspected infectious gastroenteritis presenting in hospital or the community. We undertook a systematic review to compare the accuracy of GPP tests with standard microbiology techniques. Review methods Searches in...
In the UK, the General Medical Council clearly stipulates that upon completion of training, medical students should be able to discuss the principles underlying the development of health and health service policy, including issues relating to health economics. In response, researchers from the UK and other countries have called for a need to incorporate health economics training...
• Google Scholar Search for Hema Mistry in:PubMed • Google Scholar Search for Emma Frew in:PubMed • Google Scholar Corresponding author Correspondence to Raymond Oppong. Additional information
Home monitoring has the potential to detect early pulmonary exacerbations in people with cystic fibrosis (CF), with consequent improvements in health outcomes and healthcare associated costs. This study aims to assess the effects of home monitoring on hospital admissions, quality of life, antibiotic requirements, exacerbation frequency, lung function, nutritional outcomes...
contributed to the drafting of the manuscript and to the approval of the final manuscript. TR is the guarantor. Authors information Hema Mistry and Alexander Heazell are joint lead authors. Acknowledgements
HeazellYork Health Economics Consortium, University of York, York, YO10 5NH, UKOluwaseyi Vincent AuthorsSearch for Hema Mistry in:PubMed • Google Scholar Search for Alexander E P Heazell in:PubMed • Google ... understanding of the impact of stillbirth on costs and outcomes will facilitate the evaluation of the cost-effectiveness of interventions to prevent stillbirth in a realistic manner. Authors’ information Hema
Background Total hip replacement for end stage arthritis of the hip is currently the most common elective surgical procedure. In 2007 about 7.5% of UK implants were metal-on-metal joint resurfacing (MoM RS) procedures. Due to poor revision performance and concerns about metal debris, the use of RS had declined by 2012 to about a 1% share of UK hip procedures. This study estimated...
; Augusto Azuara-Blanco, Queen’s University and Royal Victoria Hospital, Belfast H&SC Trust, Belfast; Hema Mistry, Warwick University, Warwick; Danny McAuley, Queen’s University and Royal Victoria Hospital ... . Aby Joseph (Data Manager), Ms. Christina Campbell (Statistician), Mr. Norman Waugh (Health Economist), Ms. Hema Mistry (Health Economist), Ms. Nicola Duff (Clinical Trial Administrator), Ms. Emma
People with rheumatoid arthritis are at greater risk of morbidity and mortality from cardiovascular disease than the general population. Sustained physical activity increases cardio-respiratory fitness and reduces cardiovascular disease risk factors. However, little is known about how we can effectively promote long-term participation in physical activity in patients with...
