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9 papers found.
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Economic burden of community-acquired pneumonia among elderly patients: a Japanese perspective

Background This study aimed to estimate the economic burden of community-acquired pneumonia (CAP) among elderly patients in Japan. In addition, the study evaluated the relationship between total treatment cost and CAP risk factors. Methods An administrative database was searched for elderly patients (≥ 65 years old) who had pneumonia (ICD-10 code: J12–J18) and an antibiotic...

Combined Analysis of IFN-γ, IL-2, IL-5, IL-10, IL-1RA and MCP-1 in QFT Supernatant Is Useful for Distinguishing Active Tuberculosis from Latent Infection

Welfare of Japan to Hideaki Nagai. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have

Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease

Background Although the isolation of clarithromycin (CAM)-resistant Mycobacterium avium complex (MAC) indicates a poor treatment outcome and increased mortality, there have been only a few reports on drug treatment for CAM-resistant MAC lung disease. We aimed to reveal the effectiveness of the continuation of a macrolide and the use of a multidrug regimen in the treatment of CAM...

A phase II, open-label, multicentre study to evaluate the immunogenicity and safety of an adjuvanted prepandemic (H5N1) influenza vaccine in healthy Japanese adults

Background Promising clinical data and significant antigen-sparing have been demonstrated for a pandemic H5N1 influenza split-virion vaccine adjuvanted with AS03A, an α-tocopherol-containing oil-in-water emulsion-based Adjuvant System. Although studies using this formulation have been reported, there have been no data for Japanese populations. This study therefore aimed to assess...

Diagnosis of Active Tuberculous Serositis by Antigen-Specific Interferon-γ Response of Cavity Fluid Cells

Background.To develop a more accurate methodology for diagnosing active tuberculous pleurisy, as well as peritonitis and pericardits of tuberculous origin, we established an antigen-specific interferon γ (IFN-γ)–based assay that uses cavity fluid specimens. Methods.Over a 19-month period, 155 consecutive, nonselected patients with any cavity effusion were evaluated. Study...

Identification of MICA as a Susceptibility Gene for Pulmonary Mycobacterium avium Complex Infection

Host genetic susceptibility to adult pulmonary Mycobacterium avium complex disease remains unknown. To identify genetic loci for the disease, we prepared 3 sets of pooled DNA samples from 300 patients and 300 sex-matched control subjects and genotyped 19,651 microsatellite markers in a case-control manner. D6S0009i—located in the MICA (major histocompatibility complex class I...

Strong Decays of Baryons

A model of the baryon composed of three fundamental triplets (q) which move independently in an effective potential is adopted. The wave function of the baryon is prepared in a way similar to the case of interpreting the mass levels of baryons. The strong decay probability of all baryon resonances is calculated under the above model and the result is compared with the observed...

Mass Levels and Decay Probabilities of Nucleon Resonances: An Analysis Based on the Independent Particle Like Model

It has been shown that the presently known data on baryons (isospin, spin, parity and mass) can be understood fairly well by the composite model of three fundamental triplets (fermions) of SU3 under a certain number of simple assumptions. From the same point of view as a previous paper, the following results are obtained: (i) By assuming that three fundamental fermions in the...

A Unitary Symmetric Spurion Formalism of Weak Interaction

Roles played by the unitary symmetry in the weak interactions are investigated in the framework of a spurion formalism. By maing use of spurions, currents of strongly interacting particles are constructed formally in octet form, and the interaction Hamiltonian is writen in a form of current-current interaction, which is apparently invariant under the three-dimensional unitary...