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Plasma free amino acid profiles evaluate risk of metabolic syndrome, diabetes, dyslipidemia, and hypertension in a large Asian population

Background Recently, the association of plasma free amino acid (PFAA) profile and lifestyle-related diseases has been reported. However, few studies have been reported in large Asian populations, about the usefulness of PFAAs for evaluating disease risks. We examined the ability of PFAA profiles to evaluate lifestyle-related diseases in so far the largest Asian population. Methods ...

Alteration in plasma free amino acid levels and its association with gout

Background Studies on the association of plasma-free amino acids with gout are very limited and produced conflicting results. Therefore, we sought to explore and characterize the plasma-free amino acid (PFAA) profile in patients with gout and evaluate its association with the latter. Methods Data from a total of 819 subjects (including 34 patients with gout) undergoing an annual ...

A case of adenocarcinoma arising in an ileal diverticulum resected by laparoscopic surgery

Adenocarcinoma arising in an ileal diverticulum are very rare. A 66-year-old man was recognized to have high serum CEA level and periappendiceal polycystic tumor in CT findings. Colonoscopy showed no abnormality in the ileocecal mucosa. However, the patient was suspected of appendiceal adenocarcinoma by PET/CT, which revealed FDG uptake with SUVmax of 3.9 in the tumor, and ...

Down-Regulation of microRNA-132 is Associated with Poor Prognosis of Colorectal Cancer

, Mamoru Uemura, Koji Munakata, Daisuke Okuzaki, Naotsugu Haraguchi, Hidekazu Takahashi, Junichi Nishimura, Taishi Hata, Kohei Murata, Ichiro Takemasa, Tsunekazu Mizushima, Yuichiro Doki, Masaki Mori and

Allergic Airway Inflammation by Nasal Inoculation of Particulate Matter (PM2.5) in NC/Nga Mice

To evaluate the effect of airborne particulate matter 2.5 (PM2.5) in winter on airway inflammation, water-soluble supernatant (Sup) and water-insoluble precipitate (Pre) in PM2.5 were inoculated in NC/Nga mice with high sensitivity to mite allergens. Sup with aluminum oxide was injected intraperitoneally for sensitization. Five days later, Sup, Pre or both Sup and Pre were ...

Acute exacerbation of paraneoplastic neurological syndrome after massive tumor lysis of neuroendocrine carcinoma by chemoradiotherapy

We present the case of a 68-year-old woman who presented with a swelling on the left side of her lower jaw. Biopsy revealed neuroendocrine carcinoma of the mandible. Chemoradiotherapy with carboplatin and etoposide with local irradiation induced very rapid remission of the tumor. The massive tumor remission caused severe exacerbation of symptoms, including fatigue and muscle ...

Transcription analysis of the telomeric repeat-specific retrotransposons TRAS1 and SART1 of the silkworm Bombyx mori

Hidekazu Takahashi 0 Haruhiko Fujiwara 0 0 Department of Biological Sciences, Graduate School of Science, University of Tokyo , 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan The telomeres of the

A New Family of Site-Specific Retrotransposons, SART1, Is Inserted into Telomeric Repeats of the Silkworm, Bombyx Mori

Hidekazu Takahashi 0 Satoshi Okazaki 0 Haruhiko Fujiwara 0 0 Department of Biological Sciences, Graduate School of Science, University of Tokyo , Hongo, Bunkyo-ku, Tokyo 113 The telomeres of the