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Safety, Effectiveness, and Treatment Persistence of Golimumab in Elderly Patients with Rheumatoid Arthritis in Real-World Clinical Practice in Japan

Tanabe Pharma Corporation. Disclosures. Masateru Okazaki is an employee of Janssen Pharmaceutical K.K. and may hold stock and/or stock options in the company. Hisanori Kobayashi is an employee of Janssen

Long-term effect of galantamine on cognitive function in patients with Alzheimer’s disease versus a simulated disease trajectory: an observational study in the clinical setting

Takashi Ohnishi,1 Hisanori Kobayashi,1 Toshio Yamaoka,2 Tsutomu Yajima,3 Ai Tanimura,4 Toshiya Kato,4 Kazutake Yoshizawa1 1Evidence Generation Department, Medical Affairs Division, 2Clinical Data Management

Association of early PSA decline and time to PSA progression in abiraterone acetate-treated metastatic castration-resistant prostate cancer; a post-hoc analysis of Japanese phase 2 trials

interpretation of the analyzed data of the study. All authors read and approved the final version of the manuscript. Competing interests Masahiko Nakayama, Hisanori Kobayashi, Tomihiro Takahara, Kazutake

Estimation of minimal clinically important change of the Japanese version of EQ-5D in patients with chronic noncancer pain: a retrospective research using real-world data

Background Quality of life (QoL) is routinely assessed and evaluated in medical research. However, in Japan, there is a lack of solid cutoff criteria for evaluating QoL improvement in chronic noncancer pain management. The present study was conducted to identify the minimal clinically important change (MCIC) of the Japanese version of EuroQol-5D 3L(EQ-5D) utility score and...

Predictive factors for 24 weeks sustained virologic response (SVR24) and viral relapse in patients treated with simeprevir plus peginterferon and ribavirin

, Hisanori Kobayashi, Koji Fukushima, Miwako Ishido, Yuji Komada and Kazutake Yoshizawa are employees of Janssen Pharmaceutical K.K. Informed consent in studies with human subjects All patients provided