Tanabe Pharma Corporation. Disclosures. Masateru Okazaki is an employee of Janssen Pharmaceutical K.K. and may hold stock and/or stock options in the company. Hisanori Kobayashi is an employee of Janssen
Takashi Ohnishi,1 Hisanori Kobayashi,1 Toshio Yamaoka,2 Tsutomu Yajima,3 Ai Tanimura,4 Toshiya Kato,4 Kazutake Yoshizawa1 1Evidence Generation Department, Medical Affairs Division, 2Clinical Data Management
interpretation of the analyzed data of the study. All authors read and approved the final version of the manuscript. Competing interests Masahiko Nakayama, Hisanori Kobayashi, Tomihiro Takahara, Kazutake
Background Quality of life (QoL) is routinely assessed and evaluated in medical research. However, in Japan, there is a lack of solid cutoff criteria for evaluating QoL improvement in chronic noncancer pain management. The present study was conducted to identify the minimal clinically important change (MCIC) of the Japanese version of EuroQol-5D 3L(EQ-5D) utility score and...
, Hisanori Kobayashi, Koji Fukushima, Miwako Ishido, Yuji Komada and Kazutake Yoshizawa are employees of Janssen Pharmaceutical K.K. Informed consent in studies with human subjects All patients provided