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Association between Polymorphisms of X-Ray Repair Cross Complementing Group 1 Gene and Pancreatic Cancer Risk: a Systematic Review with Meta-Analysis

Emerging evidences have shown that common genetic polymorphisms in X-ray repair cross complementing group 1 (XRCC1) gene may be associated with the development of pancreatic cancer, but individually published studies and previous meta-analyses revealed inconclusive results. The aim of our study was to investigate the association between polymorphisms in XRCC1 gene and pancreatic ...

A Simple Approach for Synthesizing of Fluorescent Carbon Quantum Dots from Tofu Wastewater

We present an investigation on carbon quantum dots (CQDs) synthesized from wastewater induced during the production of tofu. We find that tofu wastewater is a good source of raw material in making fluorescent CQDs. The corresponding CQDs can be fabricated simply via hydrothermal reaction to carbonize the organic matter in the yellow serofluid of tofu wastewater. Two sorts of CQDs ...

A sharp Trudinger type inequality for harmonic functions and its applications

The present paper introduces a sharp Trudinger type inequality for harmonic functions based on the Cauchy-Riesz kernel function, which includes modified Poisson type kernel in a half plane considered by Xu et al. (Bound. Value Probl. 2013:262, 2013). As applications, we not only obtain Morrey representations of continuous linear maps for harmonic functions in the set of all closed ...

Re-evaluation of the interrelationships among the behavioral tests in rats exposed to chronic unpredictable mild stress

, Lingtian Tan for technical assistance. This study was supported by Research Fund of Chongqing Science Technology Commission of China (NO: cstc2012jjA0112). Author Contributions Conceptualization: Hong Wang ... , Guojuan Liang, Junqing Yang. Data curation: Shengnan Kuang. Formal analysis: Ying Luo, Yang Yang. Funding acquisition: Ying Luo. Methodology: Hong Wang, Junqing Yang. 13 / 15 Project administration

Impact of meteorological factors on the incidence of bacillary dysentery in Beijing, China: A time series analysis (1970-2012)

Contributions Conceptualization: Long Yan, Juan He. Formal analysis: Long Yan, Hong Wang. Funding acquisition: Juan He. Methodology: Long Yan. Software: Long Yan. Writing ± original draft: Long Yan ... . Writing ± review & editing: Long Yan, Hong Wang, Xuan Zhang, Ming-Yue Li, Juan He. 12 / 13 1. Niyogi SK . Shigellosis. Journal of microbiology (Seoul , Korea). 2005 ; 43 ( 2 ): 133 ± 43 . Epub 2005/05/10

Metal removal and associated binding fraction transformation in contaminated river sediment washed by different types of agents

In ex-situ washing, HCl, EDTA and H2O2 solutions can effectively extract heavy metals in river sediment. Nevertheless they often target different sediment components, possibly transforming metal species into more bioavailable and hence toxic ones. This study, in batch settings, investigated the influences of different types of washing agents (i.e. HCl, EDTA and H2O2) on metal (i.e. ...

Pyrosequencing quantified methylation level of miR-124 predicts shorter survival for patients with myelodysplastic syndrome

Background Aberrant CpG island methylation has been increasingly recognized as a common event in myelodysplastic syndrome (MDS). To date, most of the previous studies of miR-124 in MDS have focused on epigenetic changes and little is known about the underlying mechanism through which miR-124 regulates CDK6 expression. Results In the present study, we employed pyrosequencing ...

Hydrogen-rich water alleviates the toxicities of different stresses to mycelial growth in Hypsizygus marmoreus

In plants, hydrogen gas (H2) enhances tolerance to several abiotic stresses, including salinity and heavy metals. However, the effect of H2 on fungal growth under different stresses remains largely unclear. In this study, hydrogen-rich water (HRW) was employed to characterize physiological roles and molecular mechanisms of H2 in the alleviation of three different stresses in ...

The herpevac trial for women: Sequence analysis of glycoproteins from viruses obtained from infected subjects

The Herpevac Trial for Women revealed that three dose HSV-2 gD vaccine was 58% protective against culture-positive HSV-1 genital disease, but it was not protective against HSV-2 infection or disease. To determine whether vaccine-induced immune responses had selected for a particular gD sequence in strains infecting vaccine recipients compared with viruses infecting control ...

The neoepitope landscape in pediatric cancers

Background Neoepitopes derived from tumor-specific somatic mutations are promising targets for immunotherapy in childhood cancers. However, the potential for such therapies in targeting these epitopes remains uncertain due to a lack of knowledge of the neoepitope landscape in childhood cancer. Studies to date have focused primarily on missense mutations without exploring gene ...

Random rotation survival forest for high dimensional censored data

Recently, rotation forest has been extended to regression and survival analysis problems. However, due to intensive computation incurred by principal component analysis, rotation forest often fails when high-dimensional or big data are confronted. In this study, we extend rotation forest to high dimensional censored time-to-event data analysis by combing random subspace, bagging ...

Prognostic factors for mortality in patients with bullous pemphigoid: a meta-analysis

Bullous pemphigoid (BP) is a chronic debilitating autoimmune blistering disease that frequently occurs in the elderly population. Previous studies have suggested a high morbidity and mortality associated with BP. However, relatively few studies have investigated prognostic factors of BP mortality, and they showed considerably various results. This meta-analysis aimed to ...

Epithelial stem cells are formed by small-particles released from particle-producing cells

Recent spatiotemporal report demonstrated that epidermal stem cells have equal potential to divide or differentiate, with no asymmetric cell division observed. Therefore, how epithelial stem cells maintain lifelong stem-cell support still needs to be elucidated. In mouse blood and bone marrow, we found a group of large cells stained strongly for eosin and containing ...

A journey without maps—Understanding the costs of caring for dependent older people in Nigeria, China, Mexico and Peru

: Rosie Mayston. Formal analysis: Rosie Mayston. Funding acquisition: Peter Lloyd-Sherlock, Martin Prince. Investigation: Peter Lloyd-Sherlock, Sara Gallardo, Hong Wang, Veronica Montes de Oca, Peter ... Ezeah, Mariella Guerra, Ana Luisa Sosa, Zhaourui Liu, Richard Uwakwe. Methodology: Rosie Mayston, Peter Lloyd-Sherlock. Project administration: Rosie Mayston, Hong Wang, Veronica Montes de Oca, Peter

AlzhCPI: A knowledge base for predicting chemical-protein interactions towards Alzheimer’s disease

Alzheimer's disease (AD) is a complicated progressive neurodegeneration disorder. To confront AD, scientists are searching for multi-target-directed ligands (MTDLs) to delay disease progression. The in silico prediction of chemical-protein interactions (CPI) can accelerate target identification and drug discovery. Previously, we developed 100 binary classifiers to predict the CPI ...

Effects of a fixed low-dose ropivacaine with different volume and concentrations on interscalene brachial plexus block: a randomized controlled trial

Background Ultrasound guidance has reduced the amount of local anesthetics to achieve a successful block. Previous studies of the relationship between the volume or concentration of local anesthetics and the effects of the block were based on relatively high doses of local anesthetics. We tested the hypothesis that providing low dose of ropivacaine at three combinations of volumes ...

Platelet counts modulate the quantitative relationship between hepatitis B viral DNA and surface antigen concentrations: a cross-sectional study of hematological, histological and viral factors

Background The concentrations of hepatitis B virus (HBV) DNA and surface antigen (HBsAg) are two critical virological variables to be monitored in chronic hepatitis B. HBsAg is derived from the HBV genome. Thus, higher HBV-DNA concentrations should implicate higher HBsAg levels. Nevertheless, the two variables do not manifest a simple linear relationship due to elusive host factor ...

Arabidopsis ubiquitin-conjugating enzyme UBC22 is required for female gametophyte development and likely involved in Lys11-linked ubiquitination

0 1 Hong Wang 1 Correspondence: Peter Bozhkov, Swedish University of Agricultural Sciences 0 National Key Laboratory of Crop Genetic Improvement, College of Plant Science and Technology, Huazhong