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58 papers found.
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The development of HIV vaccines targeting gp41 membrane-proximal external region (MPER): challenges and prospects

, surface plasmon resonance; TM, transmembrane; UCA, unmutated common ancestor; VLPs, viruslike particles. COMPLIANCE WITH ETHICS GUIDELINES Huan Liu, Xiaojie Su, Lulu Si, Lu Lu and Shibo Jiang declare that

Improved Linearity with Polarization Coulomb Field Scattering in AlGaN/GaN Heterostructure Field-Effect Transistors

Scholar Search for Yuanjie Lv in:Nature Research journals • PubMed • Google Scholar Search for Huan Liu in:Nature Research journals • PubMed • Google Scholar Search for Aijie Cheng in:Nature Research

Effects of salinity on the cellular physiological responses of Natrinema sp. J7-2

Contributions Conceptualization: Ping Shen. Formal analysis: Ming Yang, Ping Shen, Xiangdong Chen. 10 / 13 Investigation: Huan Liu, Shunxi Zhang, Chun Hu, Jian Zhang. Methodology: Yunjun Mei, Ping Shen ... , Xiangdong Chen. Supervision: Yunjun Mei. Writing ± original draft: Yunjun Mei, Huan Liu. Writing ± review & editing: Yunjun Mei. 11 / 13 glycosylation. Environmental Microbiology. 2012; 14(3): 743±753

Homocysteine exaggerates microglia activation and neuroinflammation through microglia localized STAT3 overactivation following ischemic stroke

Elevated plasma homocysteine (Hcy) levels have been indicated as a strong and modifiable risk factor of ischemic stroke; the previous studies have shown that exposure to Hcy activates cultured microglia. However, whether neurotoxicity of Hcy involves microglia activation following brain ischemia and the underlying mechanisms remains incompletely understood. The cerebral damage...

Suppression of cucumber stachyose synthase gene (CsSTS) inhibits phloem loading and reduces low temperature stress tolerance

Stachyose is the main transporting sugar in phloem of Raffinose family oligosaccharides-transporting species. Stachyose synthase (STS) is a key enzyme for stachyose biosynthesis, but the gene encoding STS is poorly characterized in cucumber (Cucumis sativus L.), which is a model plant for studying stachyose metabolism and phloem function. In this research, stachyose synthase gene...

The good, the bad, and the ugly: uncovering novel research opportunities in social media mining

Big data is ubiquitous and can only become bigger, which challenges traditional data mining and machine learning methods. Social media is a new source of data that is significantly different from conventional ones. Social media data are mostly user-generated, and are big, linked, and heterogeneous. We present the good, the bad and the ugly associated with the multi-faceted social...

Validation of Monte Carlo simulation of mammography with TLD measurement and depth dose calculation with a detailed breast model

Mean glandular dose (MGD) is not only determined by the compressed breast thickness (CBT) and the glandular content, but also by the distribution of glandular tissues in breast. Depth dose inside the breast in mammography has been widely concerned as glandular dose decreases rapidly with increasing depth. In this study, an experiment using thermo luminescent dosimeters (TLDs) was...

Low-Dimensional Halide Perovskites and Their Advanced Optoelectronic Applications

Metal halide perovskites are crystalline materials originally developed out of scientific curiosity. They have shown great potential as active materials in optoelectronic applications. In the last 6 years, their certified photovoltaic efficiencies have reached 22.1%. Compared to bulk halide perovskites, low-dimensional ones exhibited novel physical properties. The...

Cotton Area and Yield Estimation at Zhanhua County of China Using HJ-1 EVI Time Series

Cotton is a significant cash crop of China. Timely and accurate cotton area and yield estimation is useful for management decisions related to the cotton procurement and sales. This study is a first research on cotton area and yield estimation based on remote sensing at Zhanhua County which is one of the high-quality cotton production demonstration bases of China. After...

Generation of VDR Knock-Out Mice via Zygote Injection of CRISPR/Cas9 System

CRISPR/Cas9 system has become a new versatile technology for genome engineering in various species. To achieve targeted modifications at the same site in both human and mice genomes by a CRISPR/Cas9 nuclease, we designed two target sites in conserved regions of vitamin D receptor (VDR) gene, which cover more than 17 kb of chromosome region depending on the species. We first...

Optimal decisions of sharing rate and ticket price of different transportation modes in inter-city transportation corridor

Purpose: The paper concerns competition of different transportation modes coexist in inter-city transportation corridor. The purpose of this paper is to express the competitive relationship by building mathematical model and obtain the best sharing rate and the optimal ticket price of different transportation modes. Design/methodology/approach: Firstly, analyzing influencing...

Finite Element Analysis of a New Pedicle Screw-Plate System for Minimally Invasive Transforaminal Lumbar Interbody Fusion

Purpose Minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) is increasingly popular for the surgical treatment of degenerative lumbar disc diseases. The constructs intended for segmental stability are varied in MI-TLIF. We adopted finite element (FE) analysis to compare the stability after different construct fixations using interbody cage with posterior pedicle...

ZnO Hierarchical Nanostructure Photoanode in a CdS Quantum Dot-Sensitized Solar Cell

A hierarchical array of ZnO nanocones covered with ZnO nanospikes was hydrothermally fabricated and employed as the photoanode in a CdS quantum dot-sensitized solar cell (QDSSC). This QDSSC outperformed the QDSSC based on a simple ZnO nanocone photoanode in all the four principal photovoltaic parameters. Using the hierarchical photoanode dramatically increased the short circuit...

Viability of karezes (ancient water supply systems in Afghanistan) in a changing world

The Afghanistan population living far from rivers relies upon groundwater delivered from karezes (sub-horizontal tunnels). Karezes exploit unconfined groundwater in alluvial fans recharged largely by snowmelt from the Hindu Kush, the central mountain range of the country. Since the multi-year drought that began in 1998, many karezes have stopped flowing. This study characterizes...

Bioprospecting potential of halogenases from Arctic marine actinomycetes

Background Halometabolites, an important group of natural products, generally require halogenases for their biosynthesis. Actinomycetes from the Arctic Ocean have rarely been investigated for halogenases and their gene clusters associated, albeit great potential of halometabolite production has been predicted. Therefore, we initiated this research on the screening of halogenases...

Improving the osteogenesis of human bone marrow mesenchymal stem cell sheets by microRNA-21-loaded chitosan/hyaluronic acid nanoparticles via reverse transfection

Mengying Wei,4 Qian Liu,1 Jian Zhou,1 Tian Qin,1 Xiaoke Feng,1 Huan Liu,1 Zhihong Feng,1 Yimin Zhao1 1State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases

Cardiac Exposure in the Dynamic Conformal Arc Therapy, Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy of Lung Cancer

Purpose To retrospectively evaluate the cardiac exposure in three cohorts of lung cancer patients treated with dynamic conformal arc therapy (DCAT), intensity-modulated radiotherapy (IMRT), or volumetric modulated arc therapy (VMAT) at our institution in the past seven years. Methods and Materials A total of 140 lung cancer patients were included in this institutional review...