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A meta-analysis comparing the efficacy of mineralized collagen-polymethylmethacrylate and polymethylmethacrylate bone cements in the treatment of vertebral compression fractures

of meta-analysis. (XLS) S1 Checklist. PRIMSA abstract checklist. (DOCX) Author Contributions Investigation: Xiao-hui Bai, Yun-lu Wang. Validation: Yun-lu Wang. Writing – original draft: Song-feng Li

Comparison of cardiorespiratory and anesthetic effects of ketamine-midazolam-xylazine-sufentanil and tiletamine-zolazepam-xylazine in miniature pigs

: Zhiheng Zhang, Hui Bai, Bo Zhang, Meilun Shen. Data curation: Zhiheng Zhang, Hui Bai, Bo Zhang, Meilun Shen. Formal analysis: Hui Bai. Methodology: Zhiheng Zhang, Bo Zhang, Meilun Shen. Project ... administration: Li Gao. Resources: Li Gao. Software: Zhiheng Zhang, Hui Bai. Supervision: Li Gao. Validation: Bo Zhang. Visualization: Zhiheng Zhang, Bo Zhang, Meilun Shen. Writing – original draft: Zhiheng

Systematic assessment of the clinicopathological prognostic significance of tissue cytokine expression for lung adenocarcinoma based on integrative analysis of TCGA data

systematic assessment of the clinicopathological prognostic significance of tissue cytokine expression for lung adenocarcinoma based on integrative analysis of t CGA data Yuanmei Dong Yang Liu Hui ... Bai Shunchang Jiao OPEN Dysregulated intratumoral immune reactions are shaped by complex networks of cytokines, which coordinate with tumor cells to determine tumor progression and aggressiveness. In

Prognostic value of serum amyloid A in patients with COVID-19

-Hui Bai have contributed equally to this work. COVID-19; Serum amyloid A; Prognosis - Intensive Care Unit, Renmin Hospital of Wuhan University, Eastern Campus, Wuhan, China Introduction Since

Combined detection of COMP and CS846 biomarkers in experimental rat osteoarthritis: a potential approach for assessment and diagnosis of osteoarthritis

To comprehensively evaluate the diagnostic value of serum cartilage oligomeric matrix protein (COMP) and chondroitin sulfate 846 epitope (CS846) biomarkers in osteoarthritis (OA), longitudinal and combined measurement of serum COMP and CS846 were performed at different stages in the pathological process of OA in a rat model of anterior cruciate ligament transection (ACLT). Sixty...

Expression and characteristics of manganese peroxidase from Ganoderma lucidum in Pichia pastoris and its application in the degradation of four dyes and phenol

Background Manganese peroxidase (MnP) of white rot basidiomycetes, an extracellular heme enzyme, is part of a peroxidase superfamily that is capable of degrading the different phenolic compounds. Ganoderma, a white rot basidiomycete widely distributed worldwide, could secrete lignin-modifying enzymes (LME), including laccase (Lac), lignin peroxidases (LiP) and MnP. Results After...

Genetic Mechanisms Contribute to the Development of Heart Failure in Patients with Atrioventricular Block and Right Ventricular Apical Pacing

Bai Zhouying Liu Cui hong Hou Shu Zhang Jielin Pu OPEN Published: xx xx xxxx Right ventricular apical (RVA) pacing can lead to progressive left ventricular dysfunction and heart failure (HF), even in

Major vault protein suppresses lung cancer cell proliferation by inhibiting STAT3 signaling pathway

and facilitate apoptosis of lung cancer cell through inhibition of STAT3 signaling pathway. Our results suggest that MVP act as a suppressor of lung cancer. Notes Hui Bai, Chenchen Wang and Yu Qi

XB130—A Novel Adaptor Protein: Gene, Function, and Roles in Tumorigenesis

, University of Toronto, 149 College Street, Toronto, ON, Canada M5T 1P5 Received 10 February 2014; Accepted 15 May 2014; Published 5 June 2014 Academic Editor: Patrick Auberger Copyright © 2014 Xiao-Hui ... Bai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original

XB130—A Novel Adaptor Protein: Gene, Function, and Roles in Tumorigenesis

, University of Toronto, 149 College Street, Toronto, ON, Canada M5T 1P5 Received 10 February 2014; Accepted 15 May 2014; Published 5 June 2014 Academic Editor: Patrick Auberger Copyright © 2014 Xiao-Hui ... Bai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original

XB130—A Novel Adaptor Protein: Gene, Function, and Roles in Tumorigenesis

, University of Toronto, 149 College Street, Toronto, ON, Canada M5T 1P5 Received 10 February 2014; Accepted 15 May 2014; Published 5 June 2014 Academic Editor: Patrick Auberger Copyright © 2014 Xiao-Hui ... Bai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original

XB130—A Novel Adaptor Protein: Gene, Function, and Roles in Tumorigenesis

Several adaptor proteins have previously been shown to play an important role in the promotion of tumourigenesis. XB130 (AFAP1L2) is an adaptor protein involved in many cellular functions, such as cell survival, cell proliferation, migration, and gene and miRNA expression. XB130’s functional domains and motifs enable its interaction with a multitude of proteins involved in...

PKC Activation Induces Inflammatory Response and Cell Death in Human Bronchial Epithelial Cells

A variety of airborne pathogens can induce inflammatory responses in airway epithelial cells, which is a crucial component of host defence. However, excessive inflammatory responses and chronic inflammation also contribute to different diseases of the respiratory system. We hypothesized that the activation of protein kinase C (PKC) is one of the essential mechanisms of...

EHFPI: a database and analysis resource of essential host factors for pathogenic infection

High-throughput screening and computational technology has greatly changed the face of microbiology in better understanding pathogen–host interactions. Genome-wide RNA interference (RNAi) screens have given rise to a new class of host genes designated as Essential Host Factors (EHFs), whose knockdown effects significantly influence pathogenic infections. Therefore, we present the...

Preoperative Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio are Associated with the Prognosis of Group 3 and Group 4 Medulloblastoma

-wei Wang Yun-bo Zhan t ao Sun feng-jiang Zhang BinYu Ya-hui Bai Yan-min Wang Yu-chen Ji Jin-qiao Zhou Xian-zhi Liu Zhi-feng Zhang Zhen-yu Zhang Published: xx xx xxxx Inflammation and immunoreaction

Miltefosine Suppresses Hepatic Steatosis by Activating AMPK Signal Pathway

Background and Purpose It has been accepted that AMPK (Adenosine monophosphate–activated protein kinase) activation exhibits many beneficial effects on glucolipid metabolism. Lysophosphatidylcholine (LPC) is an important lysophospholipid which can improve blood glucose levels in diabetic mice and attenuate inflammation by activating AMPK signal pathway in macrophages. Synthetic...

Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK–NF-κB signaling mediated inflammation

Macrophage-orchestrated, low-grade chronic inflammation plays a pivotal role in obesity and atherogenesis. However, the underlying regulatory mechanisms remain incompletely understood. Here, we identify major vault protein (MVP), the main component of unique cellular ribonucleoprotein particles, as a suppressor for NF-κB signaling in macrophages. Both global and myeloid-specific...

Differential Gene Expression in Foxtail Millet during Incompatible Interaction with Uromyces setariae-italicae

Foxtail millet (Setaria italica) is an important food and fodder grain crop that is grown for human consumption. Production of this species is affected by several plant diseases, such as rust. The cultivar Shilixiang has been identified as resistant to the foxtail millet rust pathogen, Uromyces setariae-italicae. In order to identify signaling pathways and genes related to the...

High-throughput sequencing-based analysis of endogenetic fungal communities inhabiting the Chinese Cordyceps reveals unexpectedly high fungal diversity

Chinese Cordyceps, known in Chinese as “DongChong XiaCao”, is a parasitic complex of a fungus (Ophiocordyceps sinensis) and a caterpillar. The current study explored the endogenetic fungal communities inhabiting Chinese Cordyceps. Samples were collected from five different geographical regions of Qinghai and Tibet, and the nuclear ribosomal internal transcribed spacer-1 sequences...

Similar to Spironolactone, Oxymatrine Is Protective in Aldosterone-Induced Cardiomyocyte Injury via Inhibition of Calpain and Apoptosis-Inducing Factor Signaling

Cong-Hui Bai 0 Xiang-Chun Shen 0 Shawn B Bratton, The University of Texas MD Anderson Cancer Center, United States of America 0 1 Research Division of Pharmacology, Guiyang Medical University , Guiyang