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12 papers found.
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Dietary and genetic risk scores and incidence of type 2 diabetes

BackgroundBoth lifestyle and genetic predisposition determine the development of type 2 diabetes (T2D), and studies have indicated interactions between specific dietary components and individual genetic variants. However, it is unclear whether the importance of overall dietary habits, including T2D-related food intakes, differs depending on genetic predisposition to T2D. We...

A prospective study of dietary and supplemental zinc intake and risk of type 2 diabetes depending on genetic variation in SLC30A8

Background The solute carrier family 30 member 8 gene (SLC30A8) encodes a zinc transporter in the pancreatic beta cells and the major C-allele of a missense variant (rs13266634; C/T; R325W) in SLC30A8 is associated with an increased risk of type 2 diabetes (T2D). We hypothesized that the association between zinc intake and T2D may be modified by the SLC30A8 genotype. Results We...

Plasma enterolactone and risk of prostate cancer in middle-aged Swedish men

Purpose Enterolactone (ENL) is formed in the human gut after consumption of lignans, has estrogenic properties, and has been associated with risk of prostate cancer. We examined the association between plasma ENL levels and prostate cancer in a nested case–control study within the population-based Malmö Diet and Cancer cohort. We also examined the association between plasma ENL...

Genetic susceptibility to dyslipidemia and incidence of cardiovascular disease depending on a diet quality index in the Malmö Diet and Cancer cohort

Background By taking diet quality into account, we may clarify the relationship between genetically elevated triglycerides (TG) and low-density lipoprotein-cholesterol (LDL-C), and better understand the inconsistent results regarding genetically elevated high-density lipoprotein-cholesterol (HDL-C), and cardiovascular disease (CVD) risk. Methods We included 24,799 participants...

The chromosome 9p21 variant interacts with vegetable and wine intake to influence the risk of cardiovascular disease: a population based cohort study

Background Chromosome 9p21 variants are associated with cardiovascular disease (CVD) but not with any of its known risk markers. However, recent studies have suggested that the risk associated with 9p21 variation is modified by a prudent dietary pattern and smoking. We tested if the increased risk of CVD by the 9p21 single nucleotide polymorphism rs4977574 is modified by intakes...

The Association between Carbohydrate-Rich Foods and Risk of Cardiovascular Disease Is Not Modified by Genetic Susceptibility to Dyslipidemia as Determined by 80 Validated Variants

Background It is still unclear whether carbohydrate consumption is associated with cardiovascular disease (CVD) risk. Genetic susceptibility might modify the associations between dietary intakes and disease risk. Objectives The aim was to examine the association between the consumption of carbohydrate-rich foods (vegetables, fruits and berries, juice, potatoes, whole grains...

A High Diet Quality Is Associated with Lower Incidence of Cardiovascular Events in the Malmö Diet and Cancer Cohort

Aims To investigate if diet quality is related to incidence of cardiovascular (CV) events. Subjects and Methods A diet quality index based on the 2005 Swedish Nutrition Recommendations and the Swedish Dietary Guidelines was created and included six dietary components: saturated fatty acids, polyunsaturated fatty acids, fish and shellfish, dietary fiber, fruit and vegetables, and...

Dietary Fiber and Saturated Fat Intake Associations with Cardiovascular Disease Differ by Sex in the Malmö Diet and Cancer Cohort: A Prospective Study

Background The aim of the study was to examine associations between intake of macronutrients and dietary fiber and incident ischemic cardiovascular disease (iCVD) in men and women. Methods We used data from 8,139 male and 12,535 female participants (aged 44–73 y) of the Swedish population-based Malmö Diet and Cancer cohort. The participants were without history of CVD and...

Nutrient Patterns and Their Food Sources in an International Study Setting: Report from the EPIC Study

Background Compared to food patterns, nutrient patterns have been rarely used particularly at international level. We studied, in the context of a multi-center study with heterogeneous data, the methodological challenges regarding pattern analyses. Methodology/Principal Findings We identified nutrient patterns from food frequency questionnaires (FFQ) in the European Prospective...

Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition

Trichopoulou Dimitirios Trichopoulos Max Leenders Petra HM Peeters Dagrun Engeset Christine L Parr Guri Skeie Paula Jakszyn Mara-Jos Snchez Jos M Huerta M Luisa Redondo Aurelio Barricarte Pilar Amiano Isabel ... Drake Emily Sonestedt Gran Hallmans Ingegerd Johansson Veronika Fedirko Isabelle Romieux Pietro Ferrari Teresa Norat Anne C Vergnaud Elio Riboli Jakob Linseisen 0 Division of Cancer Epidemiology and

Macronutrient Composition of the Diet and Prospective Weight Change in Participants of the EPIC-PANACEA Study

Androniki Naska Antonia Trichopoulou Birgit Teucher Rudolf Kaaks Heiner Boeing Brian Buijsse Ingeged Johansson Go ran Hallmans Isabel Drake Emily Sonestedt Marianne Uhre Jakobsen Kim Overvad Anne Tjnneland

Combined Impact of Lifestyle Factors on Prospective Change in Body Weight and Waist Circumference in Participants of the EPIC-PANACEA Study

Trichopoulou Domenico Palli Claudia Agnoli Rosario Tumino Paolo Vineis Salvatore Panico H. Bas Bueno-de-Mesquita Monique Verschuren Isabel Drake Emily Sonestedt Tonje Braaten Sabina Rinaldi Isabelle Romieu Nadia