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Crystalline Obstruction of the male Feline Urethra

Urethra by John J. Andrews Obstructive urolithiasis, or more cor­ rectly phosphocrystalluria (since calculi rarely occur in the feline kidney or ureter), occurs quite often in the male domestic cat. The

Cultural group selection and the design of REDD+: insights from Pemba

& J. Andrews 2 Handled by Timothy Michael Waring, University of Maine , United States Evolutionary analyses of the ways humans manage natural resources have until recently focused on the costs and

The automaticity of face perception is influenced by familiarity

Timothy J. Andrews In this study, we explore the automaticity of encoding for different facial characteristics and ask whether it is influenced by face familiarity. We used a matching task in which

Emission of volatile halogenated compounds, speciation and localization of bromine and iodine in the brown algal genome model <Emphasis Type=

This study explores key features of bromine and iodine metabolism in the filamentous brown alga and genomics model Ectocarpus siliculosus. Both elements are accumulated in Ectocarpus, albeit at much lower concentration factors (2-3 orders of magnitude for iodine, and < 1 order of magnitude for bromine) than e.g. in the kelp Laminaria digitata. Iodide competitively reduces the...

Development of a Consistent and Reproducible Porcine Scald Burn Model

There are very few porcine burn models that replicate scald injuries similar to those encountered by children. We have developed a robust porcine burn model capable of creating reproducible scald burns for a wide range of burn conditions. The study was conducted with juvenile Large White pigs, creating replicates of burn combinations; 50°C for 1, 2, 5 and 10 minutes and 60°C, 70...

Validating the role of the Australian National University Alzheimer’s Disease Risk Index (ANU-ADRI) and a genetic risk score in progression to cognitive impairment in a population-based cohort of older adults followed for 12 years

Background The number of people living with dementia is expected to exceed 130 million by 2050, which will have serious personal, social and economic implications. Employing successful intervention and treatment strategies focused on disease prevention is currently the only available approach that can have an impact on the projected rates of dementia, with risk assessment being a...

Synthesis of global satellite observations of magmatic and volcanic deformation: implications for volcano monitoring & the lateral extent of magmatic domains

Global Synthetic Aperture Radar (SAR) measurements made over the past decades provide insights into the lateral extent of magmatic domains, and capture volcanic process on scales useful for volcano monitoring. Satellite-based SAR imagery has great potential for monitoring topographic change, the distribution of eruptive products and surface displacements (InSAR) at subaerial...

Unpredictable, unpreventable and impersonal medicine: global disaster response in the 21st century

contributions Both authors contributed equally to the concept of disaster response centers and integrating disaster response into the ongoing healthcare delivery system. R J Andrews composed the draft of the

Assessing the economic burden of Alzheimer’s disease patients first diagnosed by specialists

Background It is not known if there is a differential impact on Alzheimer’s disease (AD) diagnosis and outcomes if/when patients are diagnosed with cognitive decline by specialists versus non-specialists. This study examined the cost trajectories of Medicare beneficiaries initially diagnosed by specialists compared to similar patients who received their diagnosis in primary care...

Is sodium chloride worth its salt?

The choice of fluid for resuscitation of the brain-injured patient remains controversial, and the 'ideal' resuscitation fluid has yet to be identified. Large volumes of hypotonic solutions must be avoided because of the risk of cerebral swelling and intracranial hypertension. Traditionally, 0.9% sodium chloride has been used in patients at risk of intracranial hypertension, but...

Utilizing Targeted Mass Spectrometry to Demonstrate Asf1-Dependent Increases in Residue Specificity for Rtt109-Vps75 Mediated Histone Acetylation

In Saccharomyces cerevisiae, Rtt109, a lysine acetyltransferase (KAT), associates with a histone chaperone, either Vps75 or Asf1. It has been proposed that these chaperones alter the selectivity of Rtt109 or which residues it preferentially acetylates. In the present study, we utilized a label-free quantitative mass spectrometry-based method to determine the steady-state kinetic...

Art and science in the design of physically large and complex systems

BY D. J. ANDREWS * 0 0 Marine Research Group, Department of Mechanical Engineering, University College London , Torrington Place, London WC1E 7JE , UK Designs of physically large and complex (PL&C