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The Last Month of Szent-Györgyi in Groningen

JAAP J. BEINTEMA 0 0 Department of Biochemistry University of Groningen Nijenborgh 4 9747 AG Groningen , The Netherlands Albert (von) Szent-Gyo rgyi started his studies on biological oxidation

Selection Against Glycosylation in Ruminant Pancreatic Ribonucleases by Replacements in the Ancestral Carbohydrate Attachment Site

A hypothesis, proposed 25 years ago, that there is selection against glycosylation in ruminant pancreatic ribonucleases by replacement of methionine to leucine in the ancestral carbohydrate attachment site Asn–Met–Thr at residues 34–36, was experimentally confirmed. The replacement of leucine at position 35 by methionine in bovine ribonuclease resulted in a three-fold relative...