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Community-acquired pneumonia in the United Kingdom: a call to action

Organization Acknowledgements Not applicable. Funding Dr. James Chalmers, Prof. Peter Hawkey and Prof. Mary Slack received honoraria from Pfizer in connection with the development of this manuscript. Pfizer ... participate Not applicable. Consent for publication Not applicable. Competing interests Dr. James Chalmers has received research grant support from AstraZeneca, Pfizer, GlaxoSmithKline, Boehringer-Ingelheim

A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults

Background Invasive pneumococcal disease (IPD) and pneumococcal pneumonia are common and carry a significant morbidity and mortality. Current strategies to prevent pneumococcal disease are under review in the United Kingdom (UK). We conducted a systematic review to evaluate the burden of vaccine type adult pneumococcal disease specifically in the UK. Methods A systematic review...

STOPPIT Baby Follow-Up Study: The Effect of Prophylactic Progesterone in Twin Pregnancy on Childhood Outcome

Objectives To determine the long-term effects of in utero progesterone exposure in twin children. Methods This study evaluated the health and developmental outcomes of all surviving children born to mothers who participated in a double-blind, placebo-controlled trial of progesterone given for the prevention of preterm birth in twin pregnancies (STOPPIT, ISRCTN35782581). Follow-up...

Varying gestational age patterns in cesarean delivery: an international comparison

2 11 Francisco Bolumar 7 11 Ashna Mohangoo 6 11 Mika Gissler 4 5 11 Katarzyna Szamotulska 9 11 Nicholas Lack 8 11 Jan Nijhuis 10 11 Petr Velebil 11 13 Luule Sakkeus 11 14 James Chalmers 11 12 Jennifer ... ), Henrique Barros (Portugal), Ziva Novak (Slovenia), Francisco Bolumar (Spain), Karin Gottvall (Sweden), James Chalmers (UK, Scotland). This analysis was partially funded by a grant to the Euro-Peristat

Outcomes of Induction of Labour in Women with Previous Caesarean Delivery: A Retrospective Cohort Study Using a Population Database

Background There is evidence that induction of labour (IOL) around term reduces perinatal mortality and caesarean delivery rates when compared to expectant management of pregnancy (allowing the pregnancy to continue to await spontaneous labour or definitive indication for delivery). However, it is not clear whether IOL in women with a previous caesarean section confers the same...

The Effect of Changing Patterns of Obstetric Care in Scotland (1980–2004) on Rates of Preterm Birth and Its Neonatal Consequences: Perinatal Database Study

Jane Norman and colleagues analyzed linked perinatal surveillance data in Scotland and find that between 1980 and 2004 increases in spontaneous and medically induced preterm births contributed equally to the rising rate of preterm births.

Cardiovascular disease and air pollution in Scotland: no association or insufficient data and study design?

BackgroundCoronary heart disease and stroke are leading causes of mortality and ill health in Scotland, and clear associations have been found in previous studies between air pollution and cardiovascular disease. This study aimed to use routinely available data to examine whether there is any evidence of an association between short-term exposure to particulate matter (measured...

Centile charts for birthweight for gestational age for Scottish singleton births

Background Centile charts of birthweight for gestational age are used to identify low birthweight babies. The charts currently used in Scotland are based on data from the 1970s and require updating given changes in birthweight and in the measurement of gestational age since then. Methods Routinely collected data of 100,133 singleton births occurring in Scotland from 1998–2003...

UKCP: a collaborative network of cerebral palsy registers in the United Kingdom

University , 10 Colinton Rd, Edinburgh EH10 5DT , UK 3 Geraldine Surman, Researcher Sandra Bonellie, Statistics Lecturer James Chalmers, Consultant in Public Health Medicine Allan Colver, Reader in Community