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Endocan as an early biomarker of severity in patients with acute respiratory distress syndrome

Background Plasma concentrations of endocan, a proteoglycan preferentially expressed in the pulmonary vasculature, may represent a biomarker of lung (dys)function. We sought to determine whether the measurement of plasma endocan levels early in the course of acute respiratory distress syndrome (ARDS) could help predict risk of death or of prolonged ventilation. Methods All patients ...

Lymphopaenia in cardiac arrest patients

Background A decrease in circulating lymphocytes has been described as a marker of poor prognosis after septic shock; however, scarce data are available after cardiac arrest (CA). The aim of this study was to evaluate the impact of lymphopaenia after successful cardiopulmonary resuscitation. Methods This is a retrospective analysis of an institutional database including all adult ...

Recovery after critical illness: putting the puzzle together—a consensus of 29

In this review, we seek to highlight how critical illness and critical care affect longer-term outcomes, to underline the contribution of ICU delirium to cognitive dysfunction several months after ICU discharge, to give new insights into ICU acquired weakness, to emphasize the importance of value-based healthcare, and to delineate the elements of family-centered care. This ...

Recovery after critical illness: putting the puzzle together—a consensus of 29

In this review, we seek to highlight how critical illness and critical care affect longer-term outcomes, to underline the contribution of ICU delirium to cognitive dysfunction several months after ICU discharge, to give new insights into ICU acquired weakness, to emphasize the importance of value-based healthcare, and to delineate the elements of family-centered care. This ...

Recovery after critical illness: putting the puzzle together—a consensus of 29

In this review, we seek to highlight how critical illness and critical care affect longer-term outcomes, to underline the contribution of ICU delirium to cognitive dysfunction several months after ICU discharge, to give new insights into ICU acquired weakness, to emphasize the importance of value-based healthcare, and to delineate the elements of family-centered care. This ...

Respiratory support in patients with acute respiratory distress syndrome: an expert opinion

Mancebo V. Marco Ranieri B. Taylor Thompson Laurent Papazian Marcus J. Schultz Marcelo Amato Luciano Gattinoni Alain Mercat Antonio Pesenti Daniel Talmor Jean-Louis Vincent 0 0 Department of Intensive Care

Paradigm shifts in critical care medicine: the progress we have made

There have really been no single, major, advances in critical care medicine since the specialty came into existence. There has, however, been a gradual, continuous improvement in the process of care over the years, which has resulted in improved patient outcomes. Here, we will highlight just a few of the paradigm shifts we have seen in processes of critical care, including the move ...

Do we need ARDS?

Jean-Louis Vincent Carlos Santacruz - respiratory failure. As expected, cancer, pulmonary failure can not only help guide treatment but may also fibrosis and vasculitis represented the majority of