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Alteration of payload in extracellular vesicles by crosstalk with mesenchymal stem cells from different origin

The application of extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) requires customized materials to target disease or cell damage. We hypothesized that EVs exert different inflammatory effects on one recipient cell, although stem cells of different origins in humans have similar payloads. Here, the payload of EVs released by crosstalk between MSCs and...

Construction of the Nursing Diagnosis Ontology in Obstetric and Gynecologic Nursing Unit using Nursing Process and SNOMED CT

PURPOSE: This study was performed to propose an ontology methodology based on standardized nursing process as framework in obstetric and gynecologic nursing practice. METHODS: The instrument used in this study was based on the nursing diagnosis classification established by North American Nursing Diagnosis Association (NANDA) (2009-2011), fifth edition of the Nursing...

Improvement of stem cell-derived exosome release efficiency by surface-modified nanoparticles

Mesenchymal stem cells (MSCs) are pluripotent stromal cells that release extracellular vesicles (EVs). EVs contain various growth factors and antioxidants that can positively affect the surrounding cells. Nanoscale MSC-derived EVs, such as exosomes, have been developed as bio-stable nano-type materials. However, some issues, such as low yield and difficulty in quantification...

Reduced fertility caused by meiotic defects and micronuclei formation during microsporogenesis in x Brassicoraphanus

. Intergeneric hybrids; Pollen fertility; Meiosis; Micronucleus; xBrassicoraphanus - Hosub Shin, Hye Rang Park and Jeong Eun Park authors contributed equally. Introduction Hybridization and polyploidization

MYB1 transcription factor is a candidate responsible for red root skin in radish (Raphanus sativus L.)

. (Cheongju, Korea) for providing the radish cultivars. Author Contributions Conceptualization: Gibum Yi, June-Sik Kim, Jin Hoe Huh. Data curation: Gibum Yi, June-Sik Kim, Jeong Eun Park, Hosub Shin, Seung ... Hwa Yu, Jin Hoe Huh. Formal analysis: Gibum Yi, June-Sik Kim, Jeong Eun Park, Hosub Shin, Seung Hwa Yu, Jin Hoe Huh. Funding acquisition: Jin Hoe Huh. Investigation: Gibum Yi, June-Sik Kim, Jeong

Effect of green tea catechins on the pharmacokinetics of digoxin in humans

Effect of green tea catechins on the pharmacokinetics of digoxin in humans Tae-Eun Kim,1 Kwang-Hee Shin,2 Jeong-Eun Park,2 Min-Gul Kim,3 Yeo-Min Yun,4 Dong-Hee Choi,5 Kyoung Ja Kwon,5 Jongmin Lee6

Localized CCR2 Activation in the Bone Marrow Niche Mobilizes Monocytes by Desensitizing CXCR4

Inflammatory (classical) monocytes residing in the bone marrow must enter the bloodstream in order to combat microbe infection. These monocytes express high levels of CCR2, a chemokine receptor whose activation is required for them to exit the bone marrow. How CCR2 is locally activated in the bone marrow and how their activation promotes monocyte egress is not understood. Here...

Bio-barcode gel assay for microRNA

). Author information Author notesHyojin Lee & Jeong-Eun Park These authors contributed equally to this work AffiliationsDepartment of Chemistry, Seoul National University, Seoul 151-747, South KoreaHyojin ... Lee, Jeong-Eun Park & Jwa-Min Nam AuthorsSearch for Hyojin Lee in:Nature Research journals • PubMed • Google ScholarSearch for Jeong-Eun Park in:Nature Research journals • PubMed • Google ScholarSearch

The role of Eph receptors in lens function and disease

Cataract is the single largest contributor to blindness in the world, with the disease having a strong genetic component. In recent years the Eph family of receptor tyrosine kinases has been identified as a key regulator in lens clarity. In this review we discuss the roles of the Eph receptors in lens biology and cataract development.

Human Cataract Mutations in EPHA2 SAM Domain Alter Receptor Stability and Function

Alter Receptor Stability and Function Jeong Eun Park Alexander I. Son Rui Hua Lianqing Wang Xue Zhang Renping Zhou Vladimir N. Uversky, University of South Florida College of Medicine, United States of

The Ability of the Acute Physiology and Chronic Health Evaluation (APACHE) IV Score to Predict Mortality in a Single Tertiary Hospital

Jeong Eun Park Sang Hoon Yoo Gyu Rak Chon Young Hoon Sul Jae Young Moon References 1. Knaus WA , Draper EA , Wagner DP , Zimmerman JE . APACHE II: a severity of disease classification system . Crit Care

Nucleotide sequence and expression of the ncr nickel and cobalt resistance in Hafnia alvei 5-5

The structural genes for the nickel and cobalt resistance of the conjugative plasmid pEJH 501 of Hafnia alvei 5-5, contained on a SalI-EcoRI fragment of 4.8 kb, were cloned and sequenced. The DNA sequence included five genes in the following order: ncrA, ncrB, ncrC, ncrY, and ncrX. The predicted amino acid sequences of ncrA were homologous to the amino acid sequences of nreB of...

Nucleotide sequence and expression of the ncr nickel and cobalt resistance in Hafnia alvei 5-5

The structural genes for the nickel and cobalt resistance of the conjugative plasmid pEJH 501 of Hafnia alvei 5-5, contained on a SalI-EcoRI fragment of 4.8 kb, were cloned and sequenced. The DNA sequence included five genes in the following order: ncrA, ncrB, ncrC, ncrY, and ncrX. The predicted amino acid sequences of ncrA were homologous to the amino acid sequences of nreB of...

Nucleotide sequence and expression of the ncr nickel and cobalt resistance in Hafnia alvei 5-5

The structural genes for the nickel and cobalt resistance of the conjugative plasmid pEJH 501 of Hafnia alvei 5-5, contained on a SalI-EcoRI fragment of 4.8 kb, were cloned and sequenced. The DNA sequence included five genes in the following order: ncrA, ncrB, ncrC, ncrY, and ncrX. The predicted amino acid sequences of ncrA were homologous to the amino acid sequences of nreB of...

Nucleotide sequence and expression of the ncr nickel and cobalt resistance in Hafnia alvei 5-5

The structural genes for the nickel and cobalt resistance of the conjugative plasmid pEJH 501 of Hafnia alvei 5-5, contained on a SalI-EcoRI fragment of 4.8 kb, were cloned and sequenced. The DNA sequence included five genes in the following order: ncrA, ncrB, ncrC, ncrY, and ncrX. The predicted amino acid sequences of ncrA were homologous to the amino acid sequences of nreB of...

Nucleotide sequence and expression of the ncr nickel and cobalt resistance in Hafnia alvei 5-5

The structural genes for the nickel and cobalt resistance of the conjugative plasmid pEJH 501 of Hafnia alvei 5-5, contained on a SalI-EcoRI fragment of 4.8 kb, were cloned and sequenced. The DNA sequence included five genes in the following order: ncrA, ncrB, ncrC, ncrY, and ncrX. The predicted amino acid sequences of ncrA were homologous to the amino acid sequences of nreB of...

Nucleotide sequence and expression of the ncr nickel and cobalt resistance in Hafnia alvei 5-5

The structural genes for the nickel and cobalt resistance of the conjugative plasmid pEJH 501 of Hafnia alvei 5-5, contained on a SalI-EcoRI fragment of 4.8 kb, were cloned and sequenced. The DNA sequence included five genes in the following order: ncrA, ncrB, ncrC, ncrY, and ncrX. The predicted amino acid sequences of ncrA were homologous to the amino acid sequences of nreB of...

Nucleotide sequence and expression of the ncr nickel and cobalt resistance in Hafnia alvei 5-5

The structural genes for the nickel and cobalt resistance of the conjugative plasmid pEJH 501 of Hafnia alvei 5-5, contained on a SalI-EcoRI fragment of 4.8 kb, were cloned and sequenced. The DNA sequence included five genes in the following order: ncrA, ncrB, ncrC, ncrY, and ncrX. The predicted amino acid sequences of ncrA were homologous to the amino acid sequences of nreB of...