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Search: authors:"Jessica Preston"

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High-specificity detection of rare alleles with Paired-End Low Error Sequencing (PELE-Seq)

Background Polymorphic loci exist throughout the genomes of a population and provide the raw genetic material needed for a species to adapt to changes in the environment. The minor allele frequencies of rare Single Nucleotide Polymorphisms (SNPs) within a population have been difficult to track with Next-Generation Sequencing (NGS), due to the high error rate of standard methods...