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Life events and hopelessness depression: The influence of affective experience

. Supporting information S1 File. Data 1. (SAV) S2 File. Data 2. (SAV) Acknowledgments Author Contributions Conceptualization: Lihua Zhou, Jian Chen. Data curation: Lihua Zhou, Jian Chen. Formal analysis ... : Jian Chen. Funding acquisition: Lihua Zhou. Investigation: Lihua Zhou, Jian Chen. Methodology: Jian Chen. Project administration: Lihua Zhou. Resources: Lihua Zhou. This study was funded by the

Detection of Bearing Faults Using a Novel Adaptive Morphological Update Lifting Wavelet

and Technology of China , in 2017 . His research interests include machine condition monitoring . E-mail: . Yue-Jian Chen born in 1991, is a PhD candidate majoring in Mechanical Engineering at the

+mRNA expression of LRRC55 protein (leucine-rich repeat-containing protein 55) in the adult mouse brain

, Lei Hua, Qian Ma. Project administration: Yang-Yu-Xin Huang. Resources: Jian Chen. Supervision: Qiong-Yao Tang, Zhe Zhang. Writing ± original draft: Zhe Zhang. 8 / 10 9 / 10 1. Kobe B , Kajava AV

Calycosin inhibits the in vitro and in vivo growth of breast cancer cells through WDR7-7-GPR30 Signaling

Clinically, breast cancer is generally classified into estrogen receptor-positive (ER+) or estrogen receptor-negative (ER−) subtypes. The phytoestrogen calycosin has been shown to inhibit the proliferation of ER+ cells, which may be mediated by a feedback loop that involves miR-375, RAS dexamethasone-induced 1 (RASD1), and ERα. However, how calycosin acts on ER− breast cancer...

Bactericidal activity of alpha-bromocinnamaldehyde against persisters in Escherichia coli

Contributions Data curation: Liangbin Hu. Formal analysis: Wei Zhou, Yonghua Qi, Hongmei Ning, Jian Chen, Haizhen Mo. Investigation: Qingshan Shen, Wei Zhou, Jian Chen. Methodology: Qingshan Shen, Liangbin Hu

A top-down manner-based DCNN architecture for semantic image segmentation

Given their powerful feature representation for recognition, deep convolutional neural networks (DCNNs) have been driving rapid advances in high-level computer vision tasks. However, their performance in semantic image segmentation is still not satisfactory. Based on the analysis of visual mechanism, we conclude that DCNNs in a bottom-up manner are not enough, because semantic...

Tuning the transcription and translation of L-amino acid deaminase in Escherichia coli improves α-ketoisocaproate production from L-leucine

α-Ketoisocaproate (KIC) is used widely in the pharmaceutical and nutraceutical industries. In previous studies, we achieved a one-step biosynthesis of KIC from l-leucine, using an Escherichia coli whole-cell biocatalyst expressing an l-amino acid deaminase (l-AAD) from Proteus vulgaris. Herein, we report the fine-tuning of l-AAD gene expression in E. coli BL21 (DE3) at the...

CaMKIIα may modulate fentanyl-induced hyperalgesia via a CeLC-PAG-RVM-spinal cord descending facilitative pain pathway in rats

Each of the lateral capsular division of central nucleus of amygdala(CeLC), periaqueductal gray (PAG), rostral ventromedial medulla(RVM) and spinal cord has been proved to contribute to the development of opioid-induced hyperalgesia(OIH). Especially, Ca2+/calmodulin-dependent protein kinase IIα (CaMKIIα) in CeLC and spinal cord seems to play a key role in OIH modulation. However...

Color tunable Ba0.79Al10.9O17.14:xEu phosphor prepared in air via valence state control

A series of luminescent Ba0.79Al10.9O17.14:xEu (x = 0.005–0.12) phosphors were prepared by high-temperature solid-state reaction in air atmosphere. The coexistence of Eu2+ and Eu3+ was observed and verified by photoluminescence (PL) and photoluminescence excitation (PLE) spectra, X-ray photoelectron spectra (XPS), and diffuse reflection spectra. The band emission peaking at 430...

A comparative study of MEA and DEA for post-combustion CO2 capture with different process configurations

application of CCS technology is limited by high energy consumption and high cost of capture process. Post-combustion CO2 capture (PCC) technology is widely studied now because it can be & Jian Chen applied

Fusarium graminearum pyruvate dehydrogenase kinase 1 (FgPDK1) Is Critical for Conidiation, Mycelium Growth, and Pathogenicity

Pyruvate dehydrogenase kinase (PDK) is an important mitochondrial enzyme that blocks the production of acetyl-CoA by selectively inhibiting the activity of pyruvate dehydrogenase (PDH) through phosphorylation. PDK is an effectively therapeutic target in cancer cells, but the physiological roles of PDK in phytopathogens are largely unknown. To address these gaps, a PDK gene...

Improving the active expression of transglutaminase in Streptomyces lividans by promoter engineering and codon optimization

Chen 0 2 0 Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University , Wuxi , China 1 Key Laboratory of Carbohydrate Chemistry and Biotechnology

A prospective study of breast anthropomorphic measurements, volume and ptosis in 605 Asian patients with breast cancer or benign breast disease

Objectives The current study aims to summarize breast anthropomorphic measurement features in Chinese patients with breast diseases and to investigate their potential correlations with demographic factors. Materials and methods Fifteen breast anthropomorphic parameters of 605 Chinese female patients were collected prospectively. Breast ptosis status was scaled by two methods and...

Two-Step Production of Phenylpyruvic Acid from L-Phenylalanine by Growing and Resting Cells of Engineered Escherichia coli: Process Optimization and Kinetics Modeling

Phenylpyruvic acid (PPA) is widely used in the pharmaceutical, food, and chemical industries. Here, a two-step bioconversion process, involving growing and resting cells, was established to produce PPA from l-phenylalanine using the engineered Escherichia coli constructed previously. First, the biotransformation conditions for growing cells were optimized (l-phenylalanine...

Knockdown of Mediator Complex Subunit 19 Suppresses the Growth and Invasion of Prostate Cancer Cells

Prostate cancer (PCa) is one of the most common cancers in elderly men. Mediator Complex Subunit 19 (Med19) is overexpressed and plays promotional roles in many cancers. However, the roles of Med19 in PCa are still obscure. In this study, by using immunohistochemical staining, we found higher expression level of Med19 in PCa tissues than in adjacent benign prostate tissues. We...

Global analysis of uncapped mRNA changes under drought stress and microRNA-dependent endonucleolytic cleavages in foxtail millet

Background mRNA degradation plays an important role in the determination of mRNA abundance and can quickly regulate gene expression. The production of uncapped mRNAs, an important mechanism of mRNA degradation, can be initiated by decapping enzymes, endonucleases or small RNAs such as microRNAs (miRNAs). Little is known, however, about the role of uncapped mRNAs in plants under...

WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines

Background Invasive lobular carcinoma (ILC) of the breast typically presents with clinical biomarkers consistent with a favorable response to endocrine therapies, and over 90 % of ILC cases express the estrogen receptor (ER). However, a subset of ILC cases may be resistant to endocrine therapies, suggesting that ER biology is unique in ILC. Using ILC cell lines, we previously...

Palliative treatment of pelvic bone tumors using radioiodine ( 125 I) brachytherapy

Background Complete resection of pelvic bone tumors, especially recurrent and metastatic ones, is often impossible to achieve using conventional surgery. This study aimed to assess the benefits and adverse effects of computed tomography (CT)-guided radioiodine ( 125 I) brachytherapy for inoperable recurrent and metastatic bone tumors of the pelvis. Methods This was a...

HBV-Associated Postinfectious Acute Glomerulonephritis: A Report of 10 Cases

Postinfectious acute glomerulonephritis (PIGN) may occur after various bacterial and viral infections. Hepatitis B virus (HBV) infection is a cause of chronic glomerulonephritis. We report here 10 cases (ages 7–20 years-old) of chronic HBV carriers with acute glomerulonephritis, with positive glomerular staining of hepatitis B surface antigen, and detectable presence of HBV DNA...