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165 papers found.
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Bioavailability of transgenic microRNAs in genetically modified plants

Background Transgenic expression of small RNAs is a prevalent approach in agrobiotechnology for the global enhancement of plant foods. Meanwhile, emerging studies have, on the one hand, emphasized the potential of transgenic microRNAs (miRNAs) as novel dietary therapeutics and, on the other, suggested potential food safety issues if harmful miRNAs are absorbed and bioactive. For ...

Treatment and outcome of metastatic paraganglioma of the spine

paraganglioma; Spine; Retrospective study; Total en bloc spondylectomy; Adjuvant therapy - Qi Jia, Huabin Yin and Jian Yang contributed equally to this work, and all should be considered first author

Signaling pathway in development of Camellia oleifera nurse seedling grafting union

Key message The anatomical and physiological signaling pathways associated with successful scion-rootstock union in nurse seedling grafting of Camellia oleifera propagation are illustrated. Abstract Grafting, the successful union between scion and rootstock, has practical and biological importance. Nurse seedling grafting, as those practiced for Camellia oleifera, often results in ...

Automatic liver segmentation based on appearance and context information

-challenge2007/. Funding National Basic Research Program of China (2013CB328806), PI: Jian Yang; the Key Projects in the National Science & Technology Pillar Program (2013BAI01B01), PI: Jian Yang; the National Hi ... -Tech Research and Development Program (2015AA043203), PI: Jian Yang; and the National Science Foundation Program of China (81430039, 61501030), PI: Danni Ai. 1. Chen Y , Shi L , Feng Q , Yang J , Shu H

Extremal solutions for singular fractional p-Laplacian differential equations with nonlinear boundary conditions

In this paper, we establish the existence and uniqueness of extremal solutions for nonlinear boundary value problems of a singular fractional p-Laplacian differential equation involving Riemann-Liouville derivatives. Our results are obtained by constructing monotone iterative sequences of upper and lower solutions and applying the comparison result. At last, we present an example ...

The chimeric Japanese encephalitis/Dengue 2 virus protects mice from challenge by both dengue virus and JEV virulent virus

funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Jian Yang, Huiqiang Yang, Zhushi Li, Hua Lin, Yu Zhao, Wei Wang, Shuai Tan, Xianwu

Research on the water-entry attitude of a submersible aircraft

Background The water entry of a submersible aircraft, which is transient, highly coupled, and nonlinear, is complicated. After analyzing the mechanics of this process, the change rate of every variable is considered. A dynamic model is build and employed to study vehicle attitude and overturn phenomenon during water entry. Experiments are carried out and a method to organize ...

Surgical treatment of upper cervical spine metastases: a retrospective study of 39 cases

Background The surgical treatment of upper cervical spine metastases are controversial up to now. By summarizing and analyzing the clinical data of the upper cervical spine involved metastases treated surgically in our center, we mainly aimed to investigate the surgical decisions and outcomes so as to provide more references for the clinical treatment of this special and complex ...

A vessel segmentation method for multi-modality angiographic images based on multi-scale filtering and statistical models

Background Accurate segmentation of blood vessels plays an important role in the computer-aided diagnosis and interventional treatment of vascular diseases. The statistical method is an important component of effective vessel segmentation; however, several limitations discourage the segmentation effect, i.e., dependence of the image modality, uneven contrast media, bias field, and ...

Buffer-aware adaptive resource allocation scheme in LTE transmission systems

Dynamic resource allocation scheme is a key component of 3GPP long-term evolution (LTE) for satisfying quality-of-service (QoS) requirement as well as improving the system throughput. In this paper, a buffer-aware adaptive resource allocation scheme for LTE downlink transmission is proposed for improving the overall system throughput while guaranteeing the statistic QoS and keeping ...

A new solution method for wheel/rail rolling contact

To solve the problem of wheel/rail rolling contact of nonlinear steady-state curving, a three-dimensional transient finite element (FE) model is developed by the explicit software ANSYS/LS-DYNA. To improve the solving speed and efficiency, an explicit–explicit order solution method is put forward based on analysis of the features of implicit and explicit algorithm. The solution ...

Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits

0 Jacob Gratten Allan F. McRae Naomi R. Wray Jian Yang 0 Equal contributors Queensland Brain Institute, University of Queensland , Brisbane, Queensland , Australia Genome-wide association studies

CTLPScanner: a web server for chromothripsis-like pattern detection

Chromothripsis is a recently observed phenomenon in cancer cells in which one or several chromosomes shatter into pieces with subsequent inaccurate reassembly and clonal propagation. This type of event generates a potentially vast number of mutations within a relatively short-time period, and has been considered as a new paradigm in cancer development. Despite recent advances, much ...

Spine extra-osseous chordoma mimicking neurogenic tumors: report of three cases and review of the literatures

. Authors’ information Jian Yang, Xinghai Yang, and Wujun Miao should be regarded as first authors. Consent for publication Written informed consent was obtained from each patient for publication of this

Surfactant-assisted solvothermal synthesis of pure nickel submicron spheres with microwave-absorbing properties

Pure metallic nickel submicron spheres (Ni-SSs), flower-like nickel nanoflakes, and hollow micrometer-sized nickel spheres/tubes were controllably synthesized by a facile and efficient one-step solvothermal method with no reducing agent. The characteristics of these nickel nanostructures include morphology, structure, and purification. Possible synthesis mechanisms were discussed ...

VFDB 2016: hierarchical and refined dataset for big data analysis—10 years on

The virulence factor database (VFDB, http://www.mgc.ac.cn/VFs/) is dedicated to providing up-to-date knowledge of virulence factors (VFs) of various bacterial pathogens. Since its inception the VFDB has served as a comprehensive repository of bacterial VFs for over a decade. The exponential growth in the amount of biological data is challenging to the current database in regard to ...

Autosomal genetic control of human gene expression does not differ across the sexes

Background Despite their nearly identical genomes, males and females differ in risk, incidence, prevalence, severity and age-at-onset of many diseases. Sexual dimorphism is also seen in human autosomal gene expression, and has largely been explored by examining the contribution of genotype-by-sex interactions to variation in gene expression. Results In this study, we use data from ...

The role of the circle of Willis in internal carotid artery stenosis and anatomical variations: a computational study based on a patient-specific three-dimensional model

Background The aim of this study is to provide better insights into the cerebral perfusion patterns and collateral mechanism of the circle of Willis (CoW) under anatomical and pathological variations. Methods In the current study, a patient-specific three-dimensional computational model of the CoW was reconstructed based on the computed tomography (CT) images. The Carreau model was ...