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8 papers found.
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Geographic variation of parathyroidectomy in patients receiving hemodialysis: a retrospective cohort analysis

Background Secondary hyperparathyroidism (SHPT) is associated with adverse outcomes in patients receiving maintenance dialysis. Parathyroidectomy is a treatment for SHPT; whether parathyroidectomy utilization varies geographically in the US is unknown. Methods A retrospective cohort analysis was undertaken to identify all patients aged 18 years or older who were receiving in-center ...

Parathyroid hormone change after cinacalcet initiation and one-year clinical outcome risk: a retrospective cohort study

determination of manuscript content. Brian D. Bradbury, Thy Do, and Kim Lowe are employed by Amgen. Akeem A. Yusuf, Jiannong Liu, Kimberly M. Nieman, and Allan J. Collins are employed by the Chronic Disease

Pneumonia in incident dialysis patients—the United States Renal Data System

Background. Although clinical experience suggests that pneumonia may occur frequently in dialysis patients, its clinical epidemiology in that group remains poorly defined. Methods. Medicare claims were used to identify pneumonia episodes in 289 210 patients initiating dialysis in the United States between 1996 and 2001 and followed until 31 December 2003. Results. Mean patient age ...

Comparative effectiveness studies to improve clinical outcomes in end stage renal disease: the DEcIDE patient outcomes in end stage renal disease study

Background Evidence is lacking to inform providers’ and patients’ decisions about many common treatment strategies for patients with end stage renal disease (ESRD). Methods/design The DEcIDE Patient Outcomes in ESRD Study is funded by the United States (US) Agency for Health Care Research and Quality to study the comparative effectiveness of: 1) antihypertensive therapies, 2) early ...

Dialyser reuse-associated mortality and hospitalization risk in incident Medicare haemodialysis patients, 1998–1999

Background. The reuse of haemodialysers has been practiced in the United States for >20 years. We investigated mortality and hospitalization risk according to various reuse practices, testing the hypothesis that outcomes are improved in patients treated with dialysers cleaned with bleach and sterilized with formaldehyde. Methods. We studied 1998 and 1999 incident Medicare ...

Comparative mortality of hemodialysis patients at for-profit and not-for-profit dialysis facilities in the United States, 1998 to 2003: A retrospective analysis

Background Concern lingers that dialysis therapy at for-profit (versus not-for-profit) hemodialysis facilities in the United States may be associated with higher mortality, even though 4 of every 5 contemporary dialysis patients receive therapy in such a setting. Methods Our primary objective was to compare the mortality hazards of patients initiating hemodialysis at for-profit and ...

Time to target haemoglobin concentration (11 g/dl)—risk of hospitalization and mortality among incident dialysis patients

Background. Haemoglobin levels <11 g/dl are associated with increased costs, morbidity and mortality. We aimed to determine if time required to reach 11 g/dl was associated with increased risk of hospitalization or death among incident dialysis patients. Methods. We studied 29 131 patients initiating dialysis in 2002 and surviving ≥9 months. Demographic, comorbid and health care ...

Transplantation - clinical I

Introduction and Aims: Renal allograft recipients are at high risk for bone loss within the first year after transplantation. Receptor Activator of Nuclear factor-Kappa-B Ligand (RANKL) is a key regulator of the activity and survival of osteoclasts. Denosumab (Prolia®) is a humanized monoclonal antibody targeting RANKL, which is effective in the treatment of postmenopausal ...