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Decreased activity of RCAN1.4 is a potential risk factor for congenital heart disease in a Han Chinese population

Technology of Shanghai Municipality (13JC1407600) to Hongyan Wang. Liangping Cheng, Peiqiang Li, He Wang, Xueyan Yang, Huiming Zhou, Wufan Tao, Jie Tian and Hongyan Wang declare that they have no conflict of

Cholesterol esterification inhibition and gemcitabine synergistically suppress pancreatic ductal adenocarcinoma proliferation

-Ting Zhang. Project administration: Jie Tian, Ji-Xin Cheng. Resources: Jian-Ting Zhang, Ji-Xin Cheng. Supervision: Jie Tian, Ji-Xin Cheng. Validation: Jian-Ting Zhang. Visualization: Junjie Li

Monitoring inflammation injuries in the progression of atherosclerosis with contrast enhanced ultrasound molecular imaging

, Jing Guo. Funding acquisition: Yani Liu. Investigation: Jie Tian. Methodology: Jie Tian, Jun Zhang, Liping Wang, Jing Guo, Yani Liu. Project administration: Ruiying Sun, Jie Tian, Yani Liu. Software ... : Liping Wang. Validation: Jing Guo. Writing ± original draft: Ruiying Sun, Jie Tian, Yani Liu. Writing ± review & editing: Ruiying Sun, Yani Liu. 11 / 12 22. 1. Ross R . Atherosclerosis-an inflammatory

Alterations in regional homogeneity of resting-state cerebral activity in patients with chronic prostatitis/chronic pelvic pain syndrome

. Author Contributions Conceptualization: Yusong Lin, Yan Bai, Peng Liu, Jianqin Gu, Degang Ding, Jie Tian, Meiyun Wang. Data curation: Yusong Lin, Yan Bai, Degang Ding, Meiyun Wang. Formal analysis ... : Yusong Lin, Xuejuan Yang, Wei Qin, Meiyun Wang. Funding acquisition: Yan Bai, Peng Liu, Wei Qin, Meiyun Wang. Investigation: Yusong Lin, Degang Ding, Jie Tian. Methodology: Yusong Lin, Meiyun Wang

Postreconstruction filtering of 3D PET images by using weighted higher-order singular value decomposition

Background Positron emission tomography (PET) always suffers from high levels of noise due to the constraints of the injected dose and acquisition time, especially in the studies of dynamic PET imaging. To improve the quality of PET image, several approaches have been introduced to suppress noise. However, traditional filters often blur the image edges, or erase small detail, or ...

Microfiber Bragg grating for temperature and strain sensing applications

Citation: Jie TIAN, Shuhui LIU, Wenbing YU, and Peigang DENG, ?Microfiber Bragg Grating for Temperature and Strain Sensing Applications,? Photonic Sensors Microfiber Bragg Grating for Temperature and

Microfiber Bragg grating for temperature and strain sensing applications

Fiber Bragg grating is inscribed on microfiber with femtosecond laser pulses irradiation. The microfiber is fabricated by stretching a section of single mode fiber over a flame. Periodic grooves are carved on the microfiber by the laser as have been observed experimentally. The microfiber Bragg grating is demonstrated for temperature and strain sensing, and the strain sensitivity ...

Long non-coding RNAs in the regulation of myeloid cells

Long non-coding RNAs (lncRNAs) have been attracting immense research interests. The relevance of lncRNAs in biological and physiological as well as in pathological processes has increased along with the understanding of their various regulatory mechanisms. Abundant studies have indicated that lncRNAs are involved in the differentiation, proliferation, activation, and initiation of ...

Inhibition of histone acetylation by curcumin reduces alcohol-induced fetal cardiac apoptosis

Background Prenatal alcohol exposure may cause cardiac development defects, however, the underlying mechanisms are not yet clear. In the present study we have investigated the roles of histone modification by curcumin on alcohol induced fetal cardiac abnormalities during the development. Methods and results Q-PCR and Western blot results showed that alcohol exposure increased gene ...

DC fault analysis for modular multilevel converter-based system

Rated power Rated DC voltage Rated AC voltage Arm reactor Sub-module capacitor Resistance of DC cable Inductance of DC cable Value 10 MVA ±12 kV 13.8 kV 60 mH 1000 lF 0.0189 X/km 0.159 mH/km Jie ... TIAN Ph.D., professorate senior engineer,general engineer of NR Electric Co. Ltd. He works on ultra-high-voltage DC transmission, flexible DC transmission and flexible AC transmission technology. Bin LI

Prognostic Impact of Epidermal Growth Factor Receptor Overexpression in Patients with Cervical Cancer: A Meta-Analysis

Clinical trials have provided conflicting results regarding whether epidermal growth factor receptor (EGFR) overexpression predicts poor survival in cervical cancer patients. In this study, we perform a meta-analysis of the association between EGFR expression and survival in cervical cancer patients. We searched clinical studies in the Medline, PubMed, Embase, and Web of Science ...

DNA methylation regulates mouse cardiac myofibril gene expression during heart development

Huang 0 Jie Tian 1 0 Department of Biomedical Science, Charlie E. Schmidt College of Medicine, Florida Atlantic University , 777 Glades Road, Boca Raton, FL 33431 , USA 1 Department of Cardiology, Heart

Exploring the Patterns of Acupuncture on Mild Cognitive Impairment Patients Using Regional Homogeneity

Purpose To investigate the different responses to acupuncture in MCI patients and age-matched healthy subjects reflected by the Regional Homogeneity (ReHo) indices. Methods The experiment was performed at the acupoint KI3 in 12 MCI patients and 12 healthy controls, respectively. A novel non-repeated event-related (NRER) fMRI design paradigm was applied to separately detect neural ...

De novo Transcriptome Assembly of Common Wild Rice (Oryza rufipogon Griff.) and Discovery of Drought-Response Genes in Root Tissue Based on Transcriptomic Data

Background The perennial O. rufipogon (common wild rice), which is considered to be the ancestor of Asian cultivated rice species, contains many useful genetic resources, including drought resistance genes. However, few studies have identified the drought resistance and tissue-specific genes in common wild rice. Results In this study, transcriptome sequencing libraries were ...

CITED2 Mutation and methylation in children with congenital heart disease

Background The occurrence of Congenital Heart Disease (CHD) is resulted from either genetic or environmental factors or the both. The CITED2 gene deletion or mutation is associated with the development of cardiac malformations. In this study, we have investigated the role of CITED2 gene mutation and methylation in the development of Congenital Heart Disease in pediatric patients in ...

Inhibition of Histone H3K9 Acetylation by Anacardic Acid Can Correct the Over-Expression of Gata4 in the Hearts of Fetal Mice Exposed to Alcohol during Pregnancy

Background Cardiovascular malformations can be caused by abnormalities in Gata4 expression during fetal development. In a previous study, we demonstrated that ethanol exposure could lead to histone hyperacetylation and Gata4 over-expression in fetal mouse hearts. However, the potential mechanisms of histone hyperacetylation and Gata4 over-expression induced by ethanol remain ...

Comprehensive Evaluation of the Anti-Angiogenic and Anti-Neoplastic Effects of Endostar on Liver Cancer through Optical Molecular Imaging

Molecular imaging enables non-invasive monitoring of tumor growth, progression, and drug treatment response, and it has become an important tool to promote biological studies in recent years. In this study, we comprehensively evaluated the in vivo anti-angiogenic and anti-neoplastic effects of Endostar on liver cancer based on the optical molecular imaging systems including ...

Use of Indocyanine Green for Detecting the Sentinel Lymph Node in Breast Cancer Patients: From Preclinical Evaluation to Clinical Validation

Assessment of the sentinel lymph node (SLN) in patients with early stage breast cancer is vital in selecting the appropriate surgical approach. However, the existing methods, including methylene blue and nuclides, possess low efficiency and effectiveness in mapping SLNs, and to a certain extent exert side effects during application. Indocyanine green (ICG), as a fluorescent dye, ...

Dynamic prediction of building subsidence deformation with data-based mechanistic self-memory model

This paper describes a building subsidence deformation prediction model with the self-memorization principle. According to the non-linear specificity and monotonic growth characteristics of the time series of building subsidence deformation, a data-based mechanistic self-memory model considering randomness and dynamic features of building subsidence deformation is established based ...

Islet-1 May Function as an Assistant Factor for Histone Acetylation and Regulation of Cardiac Development-Related Transcription Factor Mef2c Expression

ObjectiveIslet-1 is an important transcription factor for cardiac development through mediating extensive interactions between DNA and proteins. The present study was to investigate the role of Islet-1 in regulating the expression of cardiac development-related transcription factors and mechanism. Methods and ResultsThe expression of Islet-1 and histone acetylases (HATs) subtype ...