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316 papers found.
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HNRNPA2B1 regulates the epithelial–mesenchymal transition in pancreatic cancer cells through the ERK/snail signalling pathway

Background Heterogeneous nuclear ribonucleoprotein A2B1 (HNRNPA2B1) is closely related to tumour occurrence and development, oncogene expression, apoptosis inhibition and invasion and metastasis capacities. However, its function in the epithelial–mesenchymal transition (EMT) of pancreatic cancer is not fully understood. Methods By comparing various wild-type pancreatic cancer cell ...

MoS2 with tunable surface structure directed by thiophene adsorption toward HDS and HER

MoS2 catalysts with more active sites and larger surface areas were successfully synthesized via a simple hydrothermal reaction method, and the surface structure of MoS2 was readily tailored by simply adding thiophene during the synthesis procedure. The MoS2 samples synthesized with thiophene, especially MoS2 prepared with 200 μL of thiophene, concomitantly exhibited better ...

SDF-1/CXCR7 axis regulates the proliferation, invasion, adhesion, and angiogenesis of gastric cancer cells

Background More recent studies have revealed that chemokine receptor CXCR7 plays an important role in cancer development. However, little is known about the effect of CXCR7 on the process of gastric cancer cell invasion and angiogenesis. The aim of this study is to investigate the expression of CXCR7 in gastric cancer cell lines and to evaluate the role of CXCR7 in the ...

\(B^*_{s,d} \rightarrow \mu ^+ \mu ^-\) and its impact on \(B_{s,d} \rightarrow \mu ^+ \mu ^-\)

This study investigates \(B^*_{s,d}\rightarrow \mu ^+\mu ^-\) in the dimuon distributions and the hadronic contribution \(B_{s,d}\rightarrow B^*_{s,d}\gamma \rightarrow \mu ^+\mu ^-\). The \(\mu ^+\mu ^-\) decay widths of the vector mesons \(B^*_{s,d}\) are approximately a factor of 700 larger than the corresponding scalar mesons \(B_{s,d}\). The ratio of the branching fractions ...

Does ventilator-associated event surveillance detect ventilator-associated pneumonia in intensive care units? A systematic review and meta-analysis

Yanyan Wu Jie Zhang Ming Zhu Lijuan Xiong 0 Equal contributors Department of Nosocomial Infection Management, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , 1277

Thermally stable polymer–ceramic composites for microwave antenna applications

Polymer–ceramic composites were prepared by twin screw melt extrusion with high-density polyethylene (HDPE) as the matrix and polystyrene-coated BaO–Nd2O3–TiO2 (BNT) ceramics as the filling material. Interestingly, the incorporation of polystyrene (PS) by the coating route could significantly improve the thermal behaviors of the composites (HDPE–PS/BNT), besides the temperature ...

Analysis of gene expression in the midgut of Bombyx mori during the larval molting stage

Background Insects can be models for understanding human intestinal infection and pathology. Molting, a special period during which the old insect cuticle is shed and a new one is produced, is crucial for insect development. Holometabolous insects may experience several larva-to-larva moltings to become larger, a pupal molt and adult eclosion to become adults. During the larval ...

High platelet reactivity affects the clinical outcomes of patients undergoing percutaneous coronary intervention

Background The association of platelet reactivity and clinical outcomes, especially stent thrombosis, was not so clear. We sought to investigate whether high platelet reactivity affects clinical outcomes of patients with drug eluting stents (DESs) implantation. Methods All enrolled individuals treated with DESs implantation were evaluated by PL-11, using sequentially platelet ...

Casticin induces apoptosis and G0/G1 cell cycle arrest in gallbladder cancer cells

Background Casticin, the flavonoid extracted from Vitex rotundifolia L, exerts various biological effects, including anti-inflammatory and anti-cancer activity. The aim of this study is to investigate the effects and mechanisms of casticin in human gallbladder cancer cells. Methods Human NOZ and SGC996 cells were used to perform the experiments. CCK-8 assay and colony formation ...

Location and moment tensor inversion of small earthquakes using 3D Green’s functions in models with rugged topography: application to the Longmenshan fault zone

With dense seismic arrays and advanced imaging methods, regional three-dimensional (3D) Earth models have become more accurate. It is now increasingly feasible and advantageous to use a 3D Earth model to better locate earthquakes and invert their source mechanisms by fitting synthetics to observed waveforms. In this study, we develop an approach to determine both the earthquake ...

Genome-Wide Discovery of DNA Polymorphisms in Mei (Prunus mume Sieb. et Zucc.), an Ornamental Woody Plant, with Contrasting Tree Architecture and their Functional Relevance for Weeping Trait

Next-generation sequencing technologies provide opportunities to ascertain the genetic basis of phenotypic differences, even in the closely related cultivars via detection of large amount of DNA polymorphisms. In this study, we performed whole-genome re-sequencing of two mei cultivars with contrasting tree architecture. 75.87 million 100 bp pair-end reads were generated, with 92 % ...

In situ catalytic upgrading of heavy crude oil through low-temperature oxidation

The low-temperature catalytic oxidation of heavy crude oil (Xinjiang Oilfield, China) was studied using three types of catalysts including oil-soluble, water-soluble, and dispersed catalysts. According to primary screening, oil-soluble catalysts, copper naphthenate and manganese naphthenate, are more attractive, and were selected to further investigate their catalytic performance ...

Growth enhancing effect of LBL-assembled magnetic nanoparticles on primary bone marrow cells

pathogenesis and diagnostic method, bone scaffold material and bone repair. Jie Zhang received his BSc degree in biomedical engineering from Southeast University in 2013. Now he is pursuing his master degree

Theoretical Studies of Tunable Localized Surface Plasmon Resonance of Gold-Dielectric Multilayered Nanoshells

Tunable properties of localized surface plasmon resonances (LSPR) of gold-dielectric multilayered nanoshells are studied by quasi-static theory and plasmon hybridization theory. Multilayered nanoshells with the gold core and nanoshell separated by a spacer layer exhibit strong coupling between the core and nanoshell plasmon resonance modes. It is found that the absorption spectra ...

Quality of life in Chinese family caregivers for elderly people with chronic diseases

Background Inadequate studies have been conducted in China to examine quality of life in family caregivers. Quality of life in family caregivers for elderly people with chronic diseases was evaluated, and the demographic and characteristic factors of both elderly people and their caregivers were explored. Methods The 36-Item Short Form Health Survey (SF-36) was used to assess ...

China suboptimal health cohort study: rationale, design and baseline characteristics

Background Suboptimal health status (SHS) is a physical state between health and disease, characterized by the perception of health complaints, general weakness, chronic fatigue and low energy levels. SHS is proposed by the ancient concept of traditional Chinese medicine (TCM) from the perspective of preservative, predictive and personalized (precision) medicine. We previously ...

Herpes simplex virus 1 UL41 protein abrogates the antiviral activity of hZAP by degrading its mRNA

Background The zinc finger antiviral protein (ZAP) is a host restriction factor that inhibits the replication of various viruses by degradation of certain viral mRNA. However, previous study demonstrated that ectopic expression of rat ZAP did not suppress the replication of herpes simplex virus type 1 (HSV-1), an archetypal member of the alphaherpesvirus subfamily, and the ...

A note on the optimality condition for a bilevel programming

The equality type Mordukhovich coderivative rule for a solution mapping to a second-order cone constrained parametric variational inequality is derived under the constraint nondegenerate condition, which improves the result published recently. The rule established is then applied to deriving a necessary and sufficient local optimality condition for a bilevel programming with a ...