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12 papers found.
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MoS2 with tunable surface structure directed by thiophene adsorption toward HDS and HER

MoS2 catalysts with more active sites and larger surface areas were successfully synthesized via a simple hydrothermal reaction method, and the surface structure of MoS2 was readily tailored by simply adding thiophene during the synthesis procedure. The MoS2 samples synthesized with thiophene, especially MoS2 prepared with 200 μL of thiophene, concomitantly exhibited better ...

Growth enhancing effect of LBL-assembled magnetic nanoparticles on primary bone marrow cells

pathogenesis and diagnostic method, bone scaffold material and bone repair. Jie Zhang received his BSc degree in biomedical engineering from Southeast University in 2013. Now he is pursuing his master degree

Targeting stem cell signaling pathways for drug discovery: advances in the Notch and Wnt pathways

Signaling pathways transduce extracellular stimuli into cells through molecular cascades to regulate cellular functions. In stem cells, a small number of pathways, notably those of TGF-β/BMP, Hedgehog, Notch, and Wnt, are responsible for the regulation of pluripotency and differentiation. During embryonic development, these pathways govern cell fate specifications as well as the ...

Mechanism of gold nanoparticle induced simultaneously increased PCR efficiency and specificity

Gold nanoparticles (AuNPs) have been reported to induce faster heat transfer of polymerase chain reaction (PCR) solution to enhance PCR efficiency. AuNPs can also increase the specificity of PCR by functioning analogously to single-stranded DNA binding protein (SSB). However, the simple structure of AuNPs makes it difficult to determine how AuNPs affect PCR efficiency and ...

The propagation of seafloor spreading in the southwestern subbasin, South China Sea

On the basis of the summary of basic characteristics of propagation, the dynamic model of the tectonic evolution in the Southwestern Subbasin (SWSB), South China Sea (SCS), has been established through high resolution multi-beam swatch bathymetry and multi-channel seismic profiles, combined with magnetic anomaly analysis. Spreading propagates from NE to SW and shows a transition ...

SELDI-TOF-MS in chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) has a profound impact on daily life, yet remains underdiagnosed and undertreated. This study aims to discover potential protein biomarkers for diagnosis and classification of COPD. Fifty-seven COPD patients and 40 controls were divided into a training set (30 COPD patients, 20 healthy controls) and a test set (27 COPD patients, 20 ...

A comparison of the Medieval Warm Period, Little Ice Age and 20th century warming simulated by the FGOALS climate system model

To compare differences among the Medieval Warm Period (MWP), Little Ice Age (LIA), and 20th century global warming (20CW), six sets of transient and equilibrium simulations were generated using the climate system model FGOALS_gl. This model was developed by the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics, Institute of ...

Increased COMT expression in pancreatic cancer and correlation with clinicopathologic parameters

Catechol-O-methyl transferase (COMT) is an enzyme involved in estrogen metabolism. Proteomic and immunoproteomic screens suggested COMT might be an immunogenic membrane antigen in human pancreatic cancer. The aim of this study was to investigate the dynamic expression of COMT in pancreatic ductal adenocarcinoma (PDAC) and noncancerous pancreatic tissue, and to determine the ...

Copper ions influence the toxicity of β-amyloid(1–42) in a concentration-dependent manner in a Caenorhabditis elegans model of Alzheimer’s disease

β-amyloid (Aβ) and copper play important roles in the pathogenesis of Alzheimer’s disease (AD). However, the behavioral correlativity and molecular mechanisms of Aβ and copper toxicity have been investigated less often. In the present study, we investigated the interaction and toxicity of Aβ1–42 and copper in the Aβ1–42 transgenic Caenorhabditis elegans worm model CL2006. Our data ...

AURKB and MAPK involvement in the regulation of the early stages of mouse zygote development

Aurora kinases have become a hot topic for research as they have been found to play an important role in various stages of mitotic cell division and to participate in malignant conversions of tumors. The participation of Aurora kinases in the regulation of oocyte meiosis has been recently reported, but their participation in mammalian early embryonic development remained unclear. ...

Induced temperature-dependent DNA degradation by C60 without photoactivation

This study shows that C60 can degrade pBR322 plasmid DNA at room temperature without photoactivation. The degradation was enhanced by increasing incubation temperature, reaction time or C60 concentration. We also found that superoxide radical anions (O 2 −· ) were formed in the C60 solution. Superoxide dismutase significantly inhibited DNA cleavage and O 2 −· generation induced by ...

Toxicity of the brominated flame retardant tris-(2,3-dibromopropyl) isocyanurate in zebrafish (Danio rerio)

Tris-(2,3-dibromopropyl) isocyanurate (TBC) is a heterocyclic brominated flame retardant that was recently detected in the environment in China. TBC is semi-volatile and can accumulate in the lipid of some species, but little is known about its effect on aquatic organisms. We exposed adult zebrafish to 0, 0.25, 1 and 4 mg/L TBC for 28 d and measured the effect on survival, growth, ...