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Facility location with double-peaked preferences

sufficiently close for the school to be easily accessible by the Aris Filos-Ratsikas and Jie Zhang were supported by the ERC Advanced Grant 321171 (ALGAME) and the Sino-Danish Center for the Theory of

Effect of Base Oil Structure on Elastohydrodynamic Friction

The EHD friction properties of a wide range of base fluids have been measured and compared in mixed sliding–rolling conditions at three temperatures and two pressures. The use of tungsten carbide ball and disc specimens enabled high mean contact pressures of 1.5 and 2.0 GPa to be obtained, comparable to those present in many rolling bearings. The measurements confirm the importance ...

On the Mechanism of ZDDP Antiwear Film Formation

Zinc dialkyldithiophosphate additives are used to control wear and inhibit oxidation in almost all engine oils as well as many other types of lubricant. They limit wear primarily by forming a thick, protective, phosphate glass-based tribofilm on rubbing surfaces. This film formation can occur at low temperatures and is relatively indifferent to the chemical nature of the substrate. ...

Genome-Wide Discovery of DNA Polymorphisms in Mei (Prunus mume Sieb. et Zucc.), an Ornamental Woody Plant, with Contrasting Tree Architecture and their Functional Relevance for Weeping Trait

Next-generation sequencing technologies provide opportunities to ascertain the genetic basis of phenotypic differences, even in the closely related cultivars via detection of large amount of DNA polymorphisms. In this study, we performed whole-genome re-sequencing of two mei cultivars with contrasting tree architecture. 75.87 million 100 bp pair-end reads were generated, with 92 % ...

Analysis of peginterferon β-1a exposure and Gd-enhanced lesion or T2 lesion response in relapsing-remitting multiple sclerosis patients

The effect of subcutaneous (SC) peginterferon β-1a exposure on reduction of gadolinium-enhanced (Gd+) lesion count over time was evaluated in patients with relapsing-remitting multiple sclerosis (RRMS) in a Phase 3 study (ADVANCE). Patients were randomized to receive SC injections of placebo (n = 500), 125 mcg every-2-weeks (n = 512), or 125 mcg every-4-weeks (n = 500) for 1 year, ...

Optical networks special issue based on selected IEEE ICOCN 2014 papers

, People's Republic of China 5 Calvin C. K. Chan, Chinese University of Hong Kong, Jie Zhang, Beijing University of Posts and Telecommunications , PR China - reviewers. All these papers and talks are ... University of Alberta and the Canadian NSERC Industrial R&D Fellowship. Jie Zhang received his B.E. degree in Communication Engineering and his Ph.D. degree in Electromagnetic Field and Microwave Technology

Implementing Retail Category Management: a Model-Based Approach to Setting Optimal Markups

This study proposes a model-based approach for implementing retail category management (CM) with a focus on markup decisions. We construct a Bayesian econometric model that offers a comprehensive portrait of own- and cross-price effects on sales of individual brands in a category, as well as price reactions driven by their manufacturers’ price setting behavior. We then derive ...

The c-Myc–LDHA axis positively regulates aerobic glycolysis and promotes tumor progression in pancreatic cancer

in pancreatic cancer. Treatment with 2-Deoxy-D-glucose, an inhibitor of anaerobic glycolysis, completely blocked the oncogenic roles of c-Myc-LDHA signaling. Taken Tian-Lin He and Yi-Jie Zhang have

Confining Liquids on Silicon Surfaces to Lubricate MEMS

Liquid lubrication may provide a solution to the problem of high friction and wear in micro-electro-mechanical systems. Although the effectiveness of this approach has been demonstrated in laboratory-based friction tests, practical constraints prevent it from being applied in commercial devices. The main problem is how to position the lubricant on a silicon surface in order to ...

Continuous Cardiac Output Monitoring: What Do Validation Studies Tell Us?

Medical does provide equipment as well as technical support. Li Huang and Jie Zhang declare that they have no conflict of interest. Human and Animal Rights and Informed Consent This article does not

Synthesis and Characterization of High-Purity Bismuth Nanowires via Seed-Assisted Growth Approach

Nanowires are considered as high-performance thermoelectric materials with large Seebeck coefficients due to quantum confinement and low thermal conductivity because of enhanced boundary scattering of phonons. In this work, a seed-assisted growth method has been developed to synthesize high-purity bismuth nanowires. The bismuth seeds were first synthesized by reducing BiCl3 in the ...

A Sugar Gustatory Receptor Identified from the Foregut of Cotton Bollworm Helicoverpa armigera

Wei Xu Hui-Jie Zhang Alisha Anderson 0 ) CSIRO Ecosystem Sciences , Black Mountain, Australian Capital Territory 2601, Australia Helicoverpa armigera (Hbner) is one of the most polyphagous and

Unique mechanical properties of nanostructured transparent MgAl2O4 ceramics

Nanoindentation tests were performed on nanostructured transparent magnesium aluminate (MgAl2O4) ceramics to determine their mechanical properties. These tests were carried out on samples at different applied loads ranging from 300 to 9,000 μN. The elastic recovery for nanostructured transparent MgAl2O4 ceramics at different applied loads was derived from the force-depth data. The ...

Comparative efficacy of everolimus plus exemestane versus fulvestrant for hormone-receptor-positive advanced breast cancer following progression/recurrence after endocrine therapy: a network meta-analysis

Postmenopausal women with advanced breast cancer recurring/progressing on or after initial (adjuvant or first-line) endocrine therapy may be treated multiple times with one of several endocrine or combinatorial targeted treatment options before initiating chemotherapy. In the absence of direct head-to-head comparisons of these treatment options, an indirect comparison can inform ...

Theoretical Study of the Local Surface Plasmon Resonance Properties of Silver Nanosphere Clusters

Ye-Wan Ma Zhao-Wang Wu Li-Hua Zhang Jie Zhang Guo-Shu Jian Shi Pan The local surface plasmon resonance properties in systems consisting of silver nanosphere clusters are studied by Green's function