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146 papers found.
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Impact of universal medical insurance system on the accessibility of medical service supply and affordability of patients in China

Conceptualization: Zhiguo Zhang, Jie Zhang, Xiaoyun Pan, Liang Zhang, Si Jin. Data curation: Xiaolei Xiong, Zhiguo Zhang, Jing Ren, Jie Zhang, Shiwei Gong, Si Jin. Formal analysis: Xiaoyun Pan, Liang Zhang, Shiwei ... Gong, Si Jin. Funding acquisition: Zhiguo Zhang, Shiwei Gong. Methodology: Xiaoyun Pan, Liang Zhang, Shiwei Gong, Si Jin. Project administration: Shiwei Gong. Resources: Jie Zhang, Liang Zhang

Association between social support and health-related quality of life among Chinese seafarers: A cross-sectional study

Xiao, Jie Zhang, Chuanli Wu. Funding acquisition: Jing Xiao. Investigation: Jing Xiao, Binjun Huang, Huan Shen, Xiuli Liu, Jie Zhang, Yaqing Zhong. Methodology: Jing Xiao, Yaqing Zhong, Tianqi Hua ... . Project administration: Binjun Huang, Jie Zhang. Resources: Yuexia Gao. Supervision: Jing Xiao, Yuexia Gao. Validation: Jie Zhang, Tianqi Hua. Writing ± original draft: Jing Xiao, Binjun Huang, Yuexia

Heuristic Strategies for Persuader Selection in Contagions on Complex Networks

Individual decision to accept a new idea or product is often driven by both self-adoption and others’ persuasion, which has been simulated using a double threshold model [Huang et al., Scientific Reports 6, 23766 (2016)]. We extend the study to consider the case with limited persuasion. That is, a set of individuals is chosen from the population to be equipped with persuasion...

Abscisic acid pathway involved in the regulation of watermelon fruit ripening and quality trait evolution

Contributions Conceptualization: Yanping Wang. Data curation: Yanping Wang, Shaogui Guo, Honghe Sun. Formal analysis: Yanping Wang. Funding acquisition: Shaogui Guo, Jie Zhang, Yi Ren, Yong Xu. Investigation ... : Yanping Wang, Shouwei Tian, Jie Zhang. Methodology: Yanping Wang, Yi Ren. Project administration: Haiying Zhang, Yong Xu. Resources: Guoyi Gong. Software: Shaogui Guo, Honghe Sun. Supervision: Yanping

Vibrio vulnificus induces mTOR activation and inflammatory responses in macrophages

University for their services. Author Contributions Conceptualization: Dan-Li Xie, Meng-Meng Zheng, Yi Zheng, Hui Gao, Jie Zhang, Ting Zhang, Jian-Chun Guo, X. Frank Yang, Xiao-Ping Zhong, Yong-Liang Lou ... . Data curation: Dan-Li Xie, Meng-Meng Zheng, Yi Zheng, Hui Gao, Jie Zhang, Jian-Chun Guo, Yong-Liang Lou. Formal analysis: Dan-Li Xie, Meng-Meng Zheng, Yi Zheng, Hui Gao, Jie Zhang, Ting Zhang, Jian

miR-24-3p Suppresses Malignant Behavior of Lacrimal Adenoid Cystic Carcinoma by Targeting PRKCH to Regulate p53/p21 Pathway

MicroRNA (miRNA) may function as an oncogene or a tumor suppressor in tumorigenesis. However, the mechanism of miRNAs in adenoid cystic carcinoma (ACC) is unclear. Here, we provide evidence that miR-24-3p was downreglated and functions as a tumor suppressor in human lacrimal adenoid cystic carcinoma by suppressing proliferation and migration/invasion while promoting apoptosis...

A Gene-Oriented Haplotype Comparison Reveals Recently Selected Genomic Regions in Temperate and Tropical Maize Germplasm

The extensive genetic variation present in maize (Zea mays) germplasm makes it possible to detect signatures of positive artificial selection that occurred during temperate and tropical maize improvement. Here we report an analysis of 532,815 polymorphisms from a maize association panel consisting of 368 diverse temperate and tropical inbred lines. We developed a gene-oriented...

An Apple Fruit Fermentation (AFF) Treatment Improves the Composition of the Rhizosphere Microbial Community and Growth of Strawberry (Fragaria × ananassa Duch ‘Benihoppe’) Seedlings

Plant growth can be promoted by the application of apple fruit fermentation (AFF), despite unclear of the underlying mechanisms, the effects involved in AFF on rhizosphere microorganisms have been hypothesized. We investigated the consequences of applying AFF alone or in combination with Bacillus licheniformis to strawberry tissue culture seedlings in vitro, the analyses of...

Community Size Effects on Epidemic Spreading in Multiplex Social Networks

The dynamical process of epidemic spreading has drawn much attention of the complex network community. In the network paradigm, diseases spread from one person to another through the social ties amongst the population. There are a variety of factors that govern the processes of disease spreading on the networks. A common but not negligible factor is people’s reaction to the...

The Effect of Iron Fortification on Iron (Fe) Status and Inflammation: A Randomized Controlled Trial

Background Iron deficiency (ID) is common in toddlers in developing countries. Iron fortified or meat-based complementary foods may be effective to prevent ID. Objective Our objective was to compare iron status at 18 months and growth from 6 to 18 months in rural poor toddlers fed 3 different complementary foods. Methods The study was nested within a larger trial in which 6-month...

The N-Terminal of Aquareovirus NS80 Is Required for Interacting with Viral Proteins and Viral Replication

Reovirus replication and assembly occurs within viral inclusion bodies that formed in specific intracellular compartments of cytoplasm in infected cells. Previous study indicated that aquareovirus NS80 is able to form inclusion bodies, and also can retain viral proteins within its inclusions. To better understand how NS80 performed in viral replication and assembly, the...

Altered Activation in Cerebellum Contralateral to Unilateral Thalamotomy May Mediate Tremor Suppression in Parkinson’s Disease: A Short-Term Regional Homogeneity fMRI Study

Background Ventral intermediate nucleus thalamotomy is an effective treatment for Parkinson’s disease tremor. However, its mechanism is still unclear. Purpose We used resting-state fMRI to investigate short-term ReHo changes after unilateral thalamotomy in tremor-dominant PD, and to speculate about its possible mechanism on tremor suppression. Methods 26 patients and 31 healthy...

Extraction and Separation of Active Ingredients in Schisandra chinensis (Turcz.) Baill and the Study of their Antifungal Effects

Schisandra chinensis extracts (SEs) have traditionally been used as an oriental medicine for the treatment of various human diseases, however, their further application in the biocontrol of plant disease remains poorly understood. This study was conducted to develop eco-friendly botanical pesticides from extracts of S. chinensis and assess whether they could play a key role in...

Knowledge of Community General Practitioners and Nurses on Pre-Hospital Stroke Prevention and Treatment in Chongqing, China

Background and Purpose This study aimed to investigate the knowledge of community general practitioners (GPs) and nurses about pre-hospital stroke recognition, treatment and management and secondary stroke prevention; to identify the sociodemographic and educational factors influencing knowledge. Methods A self-designed test questionnaire was applied in a self-administered close...

High Resistance to Azithromycin in Clinical Samples from Patients with Sexually Transmitted Diseases in Guangxi Zhuang Autonomous Region, China

Azithromycin is used as an alternative medicine in patients with syphilis who are intolerant to penicillin. Nevertheless, the report of treatment failure of azithromycin for patients with syphilis has raised concerns in China in the past years. In this study, 178 patients with early syphilis, who were treated in sexually transmitted infections clinics in four cities in Guangxi...

Visceral Adipose MicroRNA 223 Is Upregulated in Human and Murine Obesity and Modulates the Inflammatory Phenotype of Macrophages

Obesity in humans and mice is typified by an activated macrophage phenotype in the visceral adipose tissue (VAT) leading to increased macrophage-mediated inflammation. microRNAs (miRNAs) play an important role in regulating inflammatory pathways in macrophages, and in this study we compared miRNA expression in the VAT of insulin resistant morbidly obese humans to a non-obese...

P-mTOR Expression and Implication in Breast Carcinoma: A Systematic Review and Meta-Analysis

Objective Phosphorylated mammalian target of rapamycin (p-mTOR) is a promising prognostic marker in many types of cancer. However, its survival benefit in patients with breast carcinoma remains unknown. The aim of the present study was to assess the relationship between p-mTOR expression and prognosis in breast carcinoma based on a systematic review and meta-analysis. Materials...

Comparison of Combined and Sequential Surgery for Proliferative Diabetic Retinopathy: A Single Surgeon Study

Purpose To compare the results of combined and consecutive surgeries to treat proliferative diabetic retinopathy and cataract. Methods Retrospective comparative study. Forty-one patients with proliferative diabetic retinopathy (PDR) were enrolled. Twenty-nine eyes for the combined surgery group and twelve eyes for the sequential group were included. All surgeries were performed...

The Role of the Carboxyl Terminus Helix C-D Linker in Regulating KCNQ3 K+ Current Amplitudes by Controlling Channel Trafficking

In the central and peripheral nervous system, the assembly of KCNQ3 with KCNQ2 as mostly heteromers, but also homomers, underlies “M-type” currents, a slowly-activating voltage-gated K+ current that plays a dominant role in neuronal excitability. KCNQ3 homomers yield much smaller currents compared to KCNQ2 or KCNQ4 homomers and KCNQ2/3 heteromers. This smaller current has been...

Legume-Cereal Intercropping Improves Forage Yield, Quality and Degradability

Intercropping legume with cereal is an extensively applied planting pattern in crop cultivation. However, forage potential and the degradability of harvested mixtures from intercropping system remain unclear. To investigate the feasibility of applying an intercropping system as a forage supply source to ruminants, two consecutive experiments (experiments 1 and 2) involving a...