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Identification and characterization of microRNAs in the intestinal tissues of sheep (Ovis aries)

administration: Lei Hou, Jianmin Wang. Resources: Lei Hou, Jianmin Wang. Software: Guizhi Wang, Tianle Chao, Jianmin Wang. Validation: Lei Hou, Jin Wang, Tianle Chao, Jianmin Wang. Writing ± original draft

Quantification of motor network dynamics in Parkinson’s disease by means of landscape and flux theory

The basal ganglia neural circuit plays an important role in motor control. Despite the significant efforts, the understanding of the principles and underlying mechanisms of this modulatory circuit and the emergence of abnormal synchronized oscillations in movement disorders is still challenging. Dopamine loss has been proved to be responsible for Parkinson’s disease. We...

Uncovering the molecular and physiological processes of anticancer leads binding human serum albumin: A physical insight into drug efficacy

Human serum albumin (HSA) has its ability to bind drug molecules and influence their efficacies. Although anticancer leads NSC48693 and NSC290956 functioned at the same mechanism, the drug efficacies were obviously distinct. To gain insight into the distinct drug efficacy, the molecular and physiological processes of anticancer leads binding HSA have been investigated via a...

A Physical Mechanism and Global Quantification of Breast Cancer

Initiation and progression of cancer depend on many factors. Those on the genetic level are often considered crucial. To gain insight into the physical mechanisms of breast cancer, we construct a gene regulatory network (GRN) which reflects both genetic and environmental aspects of breast cancer. The construction of the GRN is based on available experimental data. Three basins of...

Electrostatic forces govern the binding mechanism of intrinsically disordered histone chaperones

function in vivo without having stabilized structures, researchers are motivated to revisit the long holding idea Ministry of Science and Technology of the PeopleÂs Republic of China, Jin Wang; and The ... National Science Foundation, grant number PHY-76066, URL = https://www.nsf.gov/, National Science Foundation of American, Jin Wang. that protein function is structurally determined [ 2 ]. Accumulating

The persistence and performance of phosphate-solubilizing Gluconacetobacter liquefaciens qzr14 in a cucumber soil

The persistence and performance of plant growth-promoting microorganisms (PGPMs) in soil are considered critical features for effectiveness, yet they are poorly understood. Here, we investigated the colonization and activity of a new PGPM, phosphate-solubilizing Gluconacetobacter liquefaciens qzr14, in a pot culture experiment using cucumber as test crop for 20 days. The number...

Prognostic significance of neutrophil-to-lymphocyte ratio in diffuse large B-cell lymphoma: A meta-analysis

Background Neutrophil-to-lymphocyte ratio (NLR) has been investigated as a prognostic marker in patients with diffuse large B-cell lymphoma (DLBCL); however, the results remain controversial. This study aimed to explore the association between NLR and survival outcomes and clinicopathological factors in DLBCL. Methods Relevant studies were retrieved by searching PubMed, Embase...

Colonization with Escherichia coli EC 25 protects neonatal rats from necrotizing enterocolitis

, Jamie Golden, Anatoly V. Grishin, Henri R. Ford. Formal analysis: Debi M. Thomas, Jin Wang, Larry Wang, Anatoly V. Grishin. Investigation: Debi M. Thomas, Brandon Bell, Stephanie Papillon, Patrick ... Delaplain, Joanna Lim, Jamie Golden, Jordan Bowling, Jin Wang. Methodology: Brandon Bell, Joanna Lim, Jamie Golden, Jin Wang, Larry Wang. Project administration: Anatoly V. Grishin, Henri R. Ford

The Enhanced Photo-Electrochemical Detection of Uric Acid on Au Nanoparticles Modified Glassy Carbon Electrode

In this work, a sensitive and novel method for determining uric acid (UA) has been developed, in which the glassy carbon electrode (GCE) was modified with electrodeposition Au nanoparticles and used to monitor the concentration of UA with the assistant of visible light illumination. The morphology of the Au nanoparticles deposited on GCE surface were characterized by scanning...

CHOP favors endoplasmic reticulum stress-induced apoptosis in hepatocellular carcinoma cells via inhibition of autophagy

. Methodology: Bingshuang Ren, Shihuai Zhan, Yunfeng Fu. Software: Jun Lu. Supervision: Lianghu Huang, Jianming Tan. Writing ± original draft: Jin Wang. Writing ± review & editing: Shuiliang Wang. 15 / 17 16

Characterization of quadratic growth of extended-real-valued functions

This paper shows that the sharpest possible bound in the second-order growth condition of a proper lower semicontinuous function can be attained under some assumptions. We also establish a relationship among strong metric subregularity, quadratic growth, the positive-definiteness property of the second-order subdifferential/generalized Hessian, the strong metric regularity, and...

Unlocking the vital role of host cells in hair follicle reconstruction by semi-permeable capsules

Organ regeneration is becoming a promising choice for many patients; however, many details about the mechanisms underlying organ regeneration remain unknown. As regenerative organs, hair follicles offer a good model to study the mechanisms associated with regenerative medicine. The relevant studies have mainly focused on donor cells, and there are no systematic studies involving...

Mosaic UPD(7q)mat in a patient with silver Russell syndrome

Silver-Russell syndrome (SRS) is one of the imprinting disorders characterized by prenatal and postnatal growth restriction, relative macrocephaly, body asymmetry and characteristic facial features. ~ 10% of SRS cases are known to be associated with maternal uniparental disomy of chromosome 7 (UPD(7)mat). Mosaic maternal segmental UPD of 7q (UPD(7q)mat) is very rare, had only...

A high-speed phosphorescent LED-based visible light communication system utilizing SQGNRC precoding technique

University in 2006 and 2009, respectively. During 2009-, she studies satellite thermal design drawing analysis in China Academy of Space Technology Xi’an. Yan-Jin Wang received the bachelor degree in

Surface sediment properties and heavy metal pollution assessment in the Pearl River Estuary, China

Grain size and concentrations of heavy metals (arsenic (As), cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), lead (Pb), and zinc (Zn)) of 148 surface sediments and activities of 210Pb and heavy metal concetrantions of one sediment core from the Pearl River Estuary were analyzed. The surface sediments were dominated by silt and sandy silt. Sediment type controlled the...

Vehicle networking data-upload strategy based on mobile cloud services

While traditional vehicle network communication architecture is based on special short-range communication, it is difficult to meet the demand for quality of service of vehicle networking data transmission. The relevant data can be uploaded to the server through the mobile gateway, which can be transmitted to the target vehicle by the decision of the server, which can then extend...

Network overhead crowd management mechanism of virtual mobile Internet

It has become the hot research issue that solves the bottleneck of resource management in the development of Internet through virtualization. However, there are the challenges of mobility management, resource management, and network overhead management in the virtualization of the Internet. First, based on the mobile Internet network construction and management mode, the mobile...

Selection of key sequence-based features for prediction of essential genes in 31 diverse bacterial species

Genes that are indispensable for survival are essential genes. Many features have been proposed for computational prediction of essential genes. In this paper, the least absolute shrinkage and selection operator method was used to screen key sequence-based features related to gene essentiality. To assess the effects, the selected features were used to predict the essential genes...

Risk factors for delay of adjuvant chemotherapy in non-metastatic breast cancer patients: A systematic review and meta-analysis involving 186982 patients

Purpose Delay performance of adjuvant chemotherapy (AC) after surgery has been presented to affect survival of breast cancer patients adversely, but the risk factors for delay in initiation remain controversial. Therefore, we conducted this systematic review of the literature and meta-analysis aiming at identifying the risk factors for delay of adjuvant chemotherapy (DAC) in non...

The Universal Statistical Distributions of the Affinity, Equilibrium Constants, Kinetics and Specificity in Biomolecular Recognition

We uncovered the universal statistical laws for the biomolecular recognition/binding process. We quantified the statistical energy landscapes for binding, from which we can characterize the distributions of the binding free energy (affinity), the equilibrium constants, the kinetics and the specificity by exploring the different ligands binding with a particular receptor. The...