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Material and Optical Properties of Fluorescent Carbon Quantum Dots Fabricated from Lemon Juice via Hydrothermal Reaction

The water-soluble fluorescent carbon quantum dots (CQDs) are synthesized by utilizing lemon juice as carbon resource via a simple hydrothermal reaction. The obtained CQDs are with an average size of 3.1 nm. They reveal uniform morphology and well-crystalline and can generate bright blue-green light emission under UV or blue light irradiation. We find that the fluorescence from...

Electrochemical and optical biosensors for early-stage cancer diagnosis by using graphene and graphene oxide

Conventional instruments for cancer diagnosis including magnetic resonance imaging, computed tomography scan, are expensive and require long-waiting time, whilst the outcomes have not approached to the successful early-stage diagnosis yet. Due to the special properties of graphene-based nanocomposites, e.g., good electrical and thermal conductivity, luminescence, and mechanic...

Identification of cancer-related miRNA-lncRNA biomarkers using a basic miRNA-lncRNA network

Table). Author Contributions Data curation: Mingmin Xu. Formal analysis: Jin Zhang, Yuanyuan Chen. Investigation: Mingmin Xu. Writing ± original draft: Guangle Zhang, Cong Pian, Liangyun Zhang

Transcriptome analysis in different developmental stages of Batocera horsfieldi (Coleoptera: Cerambycidae) and comparison of candidate olfactory genes

, Zhihang Zhuo, Wei Yang. Project administration: Wei Yang. Resources: Wei Yang. Software: Hua Yang, Zhihang Zhuo, Jin Zhang, Yang Yang, Baoxin Wang, Fengrong Guan. Supervision: Wei Yang. Validation: Hua

Study on the removal and transport and migration mechanism for As with activated sludge system

In this paper, the removal of As and the transport and migration of As at the process of activated sludge system was studied. The results showed that the activated sludge system has high removal efficiency for As, and the removal efficiency could be nearly 100%. The initial concentration of As has effect on the removal efficiency, and within the experimental scope, the increase...

A Simple Approach for Synthesizing of Fluorescent Carbon Quantum Dots from Tofu Wastewater

We present an investigation on carbon quantum dots (CQDs) synthesized from wastewater induced during the production of tofu. We find that tofu wastewater is a good source of raw material in making fluorescent CQDs. The corresponding CQDs can be fabricated simply via hydrothermal reaction to carbonize the organic matter in the yellow serofluid of tofu wastewater. Two sorts of CQDs...

Editorial

Liu, Bradley University Jin Zhang, Tsinghua University , USA 1 This special issue is to honor professor Tzyh-Jong Tarn for his 80 birthday. Prof. Tarn is a world outstanding system engineering from

Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells

Pharmacology-based target identification has become a novel strategy leading to the discovery of novel pathological biomarkers. Ellagic acid (EA), a dietary polyphenol compound, exhibits potent anticancer activities; however, the underlying mechanisms remain unclear. The current study sought to determine the role and regulation of ACTN4 expression in human breast cancer...

Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells

Pharmacology-based target identification has become a novel strategy leading to the discovery of novel pathological biomarkers. Ellagic acid (EA), a dietary polyphenol compound, exhibits potent anticancer activities; however, the underlying mechanisms remain unclear. The current study sought to determine the role and regulation of ACTN4 expression in human breast cancer...

Identification of a Splicing Mutation in ITPR1 via WES in a Chinese Early-Onset Spinocerebellar Ataxia Family

Mutations in the inositol 1,4,5-triphosphate receptor type 1 gene (ITPR1) lead to SCA15, SCA16, and SCA29. To date, only a few families with SCA29 have been reported. A three-generation Chinese family including four affected persons and two unaffected persons were enrolled in this study. We conducted whole-exome sequencing (WES) of the proband DNA initially to find the causal...

Cell therapy could be a potential way to improve lipoprotein lipase deficiency

Lipoprotein lipase (LPL) deficiency is an autosomal recessive genetic disorder characterized by extreme hypertriglyceridemia, with no cure presently available. The purpose of this study was to test the possibility of using cell therapy to alleviate LPL deficiency. The LPL coding sequence was cloned into the MSCV retrovirus vector, after which MSCV-hLPL and MSCV (empty construct...

The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin

. Formal analysis: Aranzazu Mediero. Funding acquisition: Bruce Cronstein. Laura Picard, Tuere Wilder. Investigation: Jessica L. Feig, Carmen Corciulo, Hailing Liu, Jin Zhang, Miguel Perez-Aso

Candidate odorant binding proteins and chemosensory proteins in the larval chemosensory tissues of two closely related noctuidae moths, Helicoverpa armigera and H. assulta

In order to acquire enough nutrients and energy for further development, larvae need to invest a large portion of their sensory equipments to identify food sources. Yet, the molecular basis of odor-driven behavior in larvae has been poorly investigated. Information on olfactory genes, particularly odorant binding proteins (OBPs) and chemosensory proteins (CSPs) which are involved...

Preoperative platelet lymphocyte ratio as independent predictors of prognosis in pancreatic cancer: A systematic review and meta-analysis

Background Recently, the preoperative platelet to lymphocyte ratio (PLR) has been found reported to predict oncologic outcomes in multiple malignancies. However, its prognostic value in patients with pancreatic cancer (PC) remains controversial. The aim of this study was to assess the prognostic value of preoperative PLR in PC. Methods MEDLINE, EMBASE, and Cochrane databases were...

How genetic variation is affected by geographic environments and ploidy level in Erianthus arundinaceus?

Erianthus arundinaceus is not only a candidate plant for sugarcane breeding programs, but also a potential bioenergy grass. Genetic variation that is affected by geographic environments and ploidy level is very important for the utilization of Erianthus arundinaceus. In this study, effects of geographic environments and ploidy level on genetic variation were studied through...

An Empirical Assessment of Transgene Flow from a Bt Transgenic Poplar Plantation

To assess the possible impact of transgenic poplar plantations on the ecosystem, we analyzed the frequency and distance of gene flow from a mature male transgenic Populus nigra plantation carrying the Bacillus thuringiensis toxin gene (Bt poplar) and the survival of Bt poplar seeds. The resultant Bt poplar seeds occurred at a frequency of ~0.15% at 0 m to ~0.02% at 500 m from the...

Transitional cell carcinoma with extension of the renal vein and IVC tumor thrombus: report of three cases and literature review

Background Transitional cell carcinoma (TCC) originating from the renal pelvis with a venous tumor thrombus is a rare entity. However, clinicians should be aware of it because of its high malignancy and poor prognosis. Case presentation Here, we report three cases of pathologically confirmed TCC originating from the renal pelvis with extension into the renal vein or inferior vena...