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Autophagy is required for human umbilical cord mesenchymal stem cells to improve spatial working memory in APP/PS1 transgenic mouse model

Jing Gao 0 Zhuo Yang 0 0 School of Medicine, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive for Materials Ministry of Education, Nankai University , 94 Weijin Road

MRT precoding in downlink multi-user MIMO systems

This paper focuses on the design of maximum ratio transmission (MRT) precoding for multi-user multiple-input multiple-output (MU-MIMO) downlink transmission. Exiting block diagonalization (BD) precoding studies on MU-MIMO systems have the high complexity, because the transmitter precoding matrices constructed by singular value decomposition (SVD) are successively calculated twice...

In vitro and in vivo evaluation of SN-38 nanocrystals with different particle sizes

In vitro and in vivo evaluation of SN-38 nanocrystals with different particle sizes Min Chen,1,2 Wanqing Li,3 Xun Zhang,1 Ye Dong,1 Yabing Hua,1 Hui Zhang,1 Jing Gao,1 Liang Zhao,2 Ying Li,1 Aiping

Gain-of-function in Arabidopsis (GAINA) for identifying functional genes in Hevea brasiliensis

Background Forward genetics approaches are not popularly applied in non-model plants due to their complex genomes, long life cycles, backward genetic studies etc. Researchers have to adopt reverse genetic methods to characterize gene functions in non-model plants individually, the efficiency of which is usually low. Results In this study, we report a gain-of-function in...

Quantum Dots for Wide Color Gamut Displays from Photoluminescence to Electroluminescence

Monodisperse quantum dots (QDs) were prepared by low-temperature process. The remarkable narrow emission peak of the QDs helps the liquid crystal displays (LCD) and electroluminescence displays (QD light-emitting diode, QLED) to generate wide color gamut performance. The range of the color gamut for QD light-converting device (QLCD) is controlled by both the QDs and color filters...

Analysis of the local delay with slotted-ALOHA based cognitive radio ad hoc networks

We analyze the local delay of cognitive radio ad hoc networks in which secondary nodes are overlaid with a pair of primary nodes. Supposing slotted ALOHA multiple access is adopted by secondary nodes, we derive the closed-form expression of the local delay by modeling the channel occupied by primary nodes as continuous-time Markov on-off process. Furthermore, we obtain the...

Characterization of sputum biomarkers for asthma–COPD overlap syndrome [Erratum]

Characterization of sputum biomarkers for asthma-COPD overlap syndrome [Erratum] Gao J, Iwamoto H, Koskela J, et al. International Journal of Chronic Obstructive Pulmonary Disease. 2016;11:2457–2465. On page 2457, Abstract, line 3, the text “To clarify the inflammatory mediatypical for ACOS, five biomarkers, namely interleukin (IL)-13, myeloperoxidase (MPO), neutrophil gelatinase...

EHD1 confers resistance to cisplatin in non-small cell lung cancer by regulating intracellular cisplatin concentrations

Background Non-small cell lung cancer (NSCLC) is one of the most aggressive types of cancer. However, resistance to cisplatin (CDDP) remains a major challenge in NSCLC treatment. The purpose of this study was to investigate the ability of EHD1 [Eps15 homology (EH) domain - containing protein 1] to confer CDDP resistance in NSCLC cells and to investigate mechanisms of this...

AMPA Receptor Antagonist NBQX Decreased Seizures by Normalization of Perineuronal Nets

Epilepsy is a serious brain disorder with diverse seizure types and epileptic syndromes. AMPA receptor antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzoquinoxaline-2,3-dione (NBQX) attenuates spontaneous recurrent seizures in rats. However, the anti-epileptic effect of NBQX in chronic epilepsy model is poorly understood. Perineuronal nets (PNNs), specialized extracellular matrix...

Hilbert-Huang transform with adaptive waveform matching extension and its application in power quality disturbance detection for microgrid

With the significant improvement of microgrid technology, microgrid has gained large-scale application. However, the existence of intermittent distributed generations, nonlinear loads and various electrical and electronic devices causes power quality problem in microgrid, especially in islanding mode. An accurate and fast disturbance detection method which is the premise of power...

Chemokine CXCL13 mediates orofacial neuropathic pain via CXCR5/ERK pathway in the trigeminal ganglion of mice

Background Trigeminal nerve damage-induced neuropathic pain is a severely debilitating chronic orofacial pain syndrome. Spinal chemokine CXCL13 and its receptor CXCR5 were recently demonstrated to play a pivotal role in the pathogenesis of spinal nerve ligation-induced neuropathic pain. Whether and how CXCL13/CXCR5 in the trigeminal ganglion (TG) mediates orofacial pain are...

The Research on Modeling and Simulation of TFE Polymerization Process

; Accepted 13 March 2014; Published 16 April 2014 Academic Editor: Huaicheng Yan Copyright © 2014 Jing Gao Sun and Qin Cao. This is an open access article distributed under the Creative Commons Attribution

Hydrogen Sulfide Prevents Synaptic Plasticity from VD-Induced Damage via Akt/GSK-3β Pathway and Notch Signaling Pathway in Rats

Tianjin (14JCQNJC11800, 14JCZDJC35000) and 111Project (B08011). Authorship contributions statement Chunhua Liu, Xiaxia Xu and Jing Gao prepared Figs. 2-4; Chunhua Liu and Jing Gao prepared Figs. 1, 5-8

Clinicopathologic and Molecular Features of Colorectal Adenocarcinoma with Signet-Ring Cell Component

Background We performed a retrospective study to assess the clinicopathological characters, molecular alterations and multigene mutation profiles in colorectal cancer patients with signet-ring cell component. Methods Between November 2008 and January 2015, 61 consecutive primary colorectal carcinomas with signet-ring cell component were available for pathological confirmation...

De novo RNA-Seq Analysis of the Venus Clam, Cyclina sinensis, and the Identification of Immune-Related Genes

The Venus clam, Cyclina sinensis, is one of the most important bivalves in China. In recent years, increasing expansive morbidity has occurred in breeding areas, imposing significant losses on the national economy. To understand the molecular mechanisms of immune-related genes, we analyzed and sequenced hemolymph samples that were injected with two pathogenic microorganisms using...

Restoration of Motion-Blurred Image Based on Border Deformation Detection: A Traffic Sign Restoration Model

Due to the rapid development of motor vehicle Driver Assistance Systems (DAS), the safety problems associated with automatic driving have become a hot issue in Intelligent Transportation. The traffic sign is one of the most important tools used to reinforce traffic rules. However, traffic sign image degradation based on computer vision is unavoidable during the vehicle movement...

Circulating Chromogranin A as A Marker for Monitoring Clinical Response in Advanced Gastroenteropancreatic Neuroendocrine Tumors

Chromogranin A (CgA), present in the chromaffin granules of neuroendocrine cells, is a useful biomarker for the diagnosis of patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs). This study was conducted to investigate the potential role of circulating CgA in monitoring clinical response in Chinese patients with advanced GEP-NETs. Eighty patients with advanced...

Short-and long-term effects of ischemic postconditioning in STEMI patients: a meta-analysis

have no competing interests. Authors’ contributions Yining Yang put forwad the design. Jing Gao and Junyi Luo completed the work of data analysis. Yingying Zheng, Bangdang Chen and Qingjie Chen ... performed collecting related papers. The manuscript was drafted by Jing Gao and Fen Liu, and revised by Junyi Luo. Finally, Jing Gao performed submitting. All authors read and approved the final manuscript

Hesperidin inhibits HeLa cell proliferation through apoptosis mediated by endoplasmic reticulum stress pathways and cell cycle arrest

Background Hesperidin (30, 5, 9-dihydroxy-40-methoxy-7-orutinosyl flavanone) is a flavanone that is found mainly in citrus fruits and has been shown to have some anti-neoplastic effects. The aim of the present study was to investigate the effect of hesperidin on apoptosis in human cervical cancer HeLa cells and to identify the mechanism involved. Methods Cells were treated with...