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Comprehensive Proteoform Characterization of Plasma Complement Component C8αβγ by Hybrid Mass Spectrometry Approaches

acidTMHTransmembrane β-hairpinTSPThrombospondinXICExtracted ion chromatogramVojtech Franc and Jing Zhu contributed equally to this work.Electronic supplementary materialThe online version of this article ( https ... newly identified modifications may play a role in the MAC formation. - Vojtech Franc and Jing Zhu contributed equally to this work. IAA Iodoacetamide; LC Liquid chromatography; LDLRA Low-density

Strategies to enhance the production of pinoresinol and its glucosides by endophytic fungus (Phomopsis sp. XP-8) isolated from Tu-chung bark

To improve the production yield of (+)-pinoresinol (Pin), (+)-pinoresinol monoglucoside (PMG), and (+)-pinoresinol diglucoside (PDG), different methods were conducted, including co-culture with resveratrol-producing Alternaria sp. MG1 spores and addition of Tu-chung in a medium at the start of cultivation, ultrasound treatment (40 kHZ, 10 min) on 5-day culture, and addition of...

TT(N)mGCCTC inhibits archaeal family B DNA polymerases

Research journals • PubMed • Google Scholar Search for Xiao-Jing Zhu in:Nature Research journals • PubMed • Google Scholar Search for Zhong-Min Dai in:Nature Research journals • PubMed • Google Scholar ... Correspondence to Mengsheng Qiu or Xiao-Jing Zhu or Zhong-Min Dai. Electronic supplementary material Supplementary Information Rights and permissions Open Access This article is licensed under a Creative

Polyethyleneimine-capped silver nanoclusters for microRNA oligonucleotide delivery and bacterial inhibition

Polyethyleneimine-capped silver nanoclusters for microRNA oligonucleotide delivery and bacterial inhibition Chunyuan Du,1,* Haibo Yan,2,* Jichao Liang,1 Ailing Luo,1 Lingqian Wang,1 Jing Zhu,1 Huayu

The impacts of market reform on the market penetration of natural gas-fired electricity and renewable energy in China

Natural gas-fired electricity (NGFE) is expected to play a more important role in the future due to its characteristics of low pollution, high efficiency and flexibility. However, its development in China is impeded by its high regulation price compared with coal power. Market reform is therefore of vital importance to promote the penetration of NGFE. The objective of this study...

Atomic layer reversal on CeO2 (100) surface

The structure and properties of CeO2 surfaces have been intensively studied due to their importance in a lot of surface-related applications. Since most of surface techniques probe the structure information inside the outermost surface plane, the subsurface structure information has been elusive in many studies. Using the profile imaging with aberration-corrected transmission...

TNF-α mRNA is negatively regulated by microRNA-181a-5p in maturation of dendritic cells induced by high mobility group box-1 protein

). Author information Author notes Jing Zhu, Fu-Li Wang and Hai-Bin Wang contributed equally to this work. AffiliationsTrauma Research Center, First Hospital Affiliated to the Chinese PLA General Hospital ... Kidney Disease, the Chinese PLA General Hospital, Beijing, 100853, P.R. ChinaYong-Ming Yao AuthorsSearch for Jing Zhu in:Nature Research journals • PubMed • Google Scholar Search for Fu-Li Wang in:Nature

Purification and characterization of a novel glutamate dehydrogenase from Geotrichum candidum with higher alcohol and amino acid activity

Crude enzyme from Geotrichum candidum S12 exhibited high activity towards hexanol at pH 4.0, distinguishing it from currently known enzymes. To identify the dominant enzyme contributing to this activity, the crude enzyme extract was separated into different fractions by ammonium sulfate precipitation, MonoQ anion-exchange chromatography, and Sephacryl S-200 gel filtration...

Age-related changes in CD4+CD25+FOXP3+ regulatory T cells and their relationship with lung cancer

://] to Pan-Fei Hou and the projects of medical and health technology development program in Shandong province, grant 2013WS0066 [http://] to Li-Jing Zhu. The funders played a

Simulation of the Effect of Artificial Water Transfer on Carbon Stock of Phragmites australis in the Baiyangdian Wetland, China

How to explain the effect of seasonal water transfer on the carbon stocks of Baiyangdian wetland is studied. The ecological model of the relationship between the carbon stocks and water depth fluctuation of the reed was established by using STELLA software. For the first time the Michaelis-Menten equation (1) introduced the relation function between the water depth and reed...

A Resting-State Brain Functional Network Study in MDD Based on Minimum Spanning Tree Analysis and the Hierarchical Clustering

A large number of studies demonstrated that major depressive disorder (MDD) is characterized by the alterations in brain functional connections which is also identifiable during the brain’s “resting-state.” But, in the present study, the approach of constructing functional connectivity is often biased by the choice of the threshold. Besides, more attention was paid to the number...

Three-Dimensional Construction of a Rabbit Anterior Corneal Replacement for Lamellar Keratoplasty

The aim of this study was to construct a rabbit anterior corneal replacement for transplantation using acellular porcine corneal matrix (APCM) and rabbit epithelial or stromal cells. APCM was prepared from fresh porcine cornea treated with 0.5% (wt./vol.) sodium dodecyl sulfate (SDS) solution. The expanded stromal cells were first injected into APCM parallel to its surface and...

Inhibition of histone acetylation by curcumin reduces alcohol-induced fetal cardiac apoptosis

Background Prenatal alcohol exposure may cause cardiac development defects, however, the underlying mechanisms are not yet clear. In the present study we have investigated the roles of histone modification by curcumin on alcohol induced fetal cardiac abnormalities during the development. Methods and results Q-PCR and Western blot results showed that alcohol exposure increased...

Fish oil diet may reduce inflammatory levels in the liver of middle-aged rats

Innovation Center of Meat Production and Processing, Nanjing Agricultural University, Nanjing, 210095, P.R. ChinaYingqiu Li, Fan Zhao, Qiayu Wu, Mengjie Li, Yingying Zhu, Shangxin Song, Jing Zhu, Yafang Ma, He ... journals • PubMed • Google Scholar Search for Shangxin Song in:Nature Research journals • PubMed • Google Scholar Search for Jing Zhu in:Nature Research journals • PubMed • Google Scholar Search for

A general way for quantitative magnetic measurement by transmitted electrons

• PubMed • Google ScholarSearch for Jing Zhu in:Nature Research journals • PubMed • Google Scholar Contributions Prof. J.Z. put forward the theme and organized the team work on the project. D.S.S. and G.L ... on the manuscript. Competing interests The authors declare no competing financial interests. Corresponding author Correspondence to Jing Zhu. Supplementary information Word documents1.Supplementary

R&D outsourcing contract for the unverified value of tacit knowledge sharing

Purpose: The purpose of this paper is to provide a R&D outsourcing contract design framework to incent R&D outsourcing service providers sharing tacit and explicit knowledge. Design/methodology/approach: The author uses the principal-agent theory to builds multitask principal-agent model which focuses on two cases. One case is that the effort costs of explicit and tacit knowledge...

Independent prognostic value of left atrial function by two-dimensional speckle tracking imaging in patients with non -ST-segment-elevation acute myocardial infarction

infarction Chunlai Shao 0 Jing Zhu 0 Jianchang Chen Weiting Xu 0 Equal contributors Department of Cardiology, The Second Affiliated Hospital of Soochow University , Sanxiang Street 1055, Suzhou , China

Low-density lipoprotein-coupled micelles with reduction and pH dual sensitivity for intelligent co-delivery of paclitaxel and siRNA to breast tumor

Low-density lipoprotein-coupled micelles with reduction and pH dual sensitivity for intelligent co-delivery of paclitaxel and siRNA to breast tumor Wen-jing Zhu,1,* Shu-di Yang,1,* Chen-xi Qu,1 Qiao ... International Journal of Nanomedicine low-density lipoprotein-coupled micelles with reduction and ph dual sensitivity for intelligent co-delivery of paclitaxel and sirNa to breast tumor Wen-jing Zhu

A Systematic Analysis of the Structures of Heterologously Expressed Proteins and Those from Their Native Hosts in the RCSB PDB Archive

Recombinant expression of proteins has become an indispensable tool in modern day research. The large yields of recombinantly expressed proteins accelerate the structural and functional characterization of proteins. Nevertheless, there are literature reported that the recombinant proteins show some differences in structure and function as compared with the native ones. Now there...