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13 papers found.
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Impact of acupuncture treatment on the lumbar surgery rate for low back pain in Korea: A nationwide matched retrospective cohort study

curation: Kyungwon Kang, Me-riong Kim, Joon-Shik Shin. Formal analysis: Wonil Koh, Yoon Jae Lee, Me-riong Kim, Joon-Shik Shin, Jinho Lee, Jun Hwan Lee, Kyung-Min Shin, In-Hyuk Ha. Funding acquisition: In ... -Hyuk Ha. Writing ± original draft: Wonil Koh, Kyungwon Kang, Yoon Jae Lee, Me-riong Kim. Writing ± review & editing: Joon-Shik Shin, Jinho Lee, Jun-Hwan Lee, Kyung-Min Shin, In Hyuk Ha. 13 / 16 14 / 16

Association between temporomandibular disorders, chronic diseases, and ophthalmologic and otolaryngologic disorders in Korean adults: A cross-sectional study

interdisciplinary approach in an effort to extend and maximize its effect. Author Contributions Ha. Song, Sun-Young Park, Seoyoun Kim, Mia Kim. Conceptualization: Hyun-Seop Song, Joon-Shik Shin, Jinho Lee, Me ... Park, Seoyoun Kim, Mia Kim, In-Hyuk Methodology: Yoon Jae Lee, Jae-Heung Cho, Koh-Woon Kim, Yeoncheol Park, Hyun Jin Project administration: Hyun-Seop Song, Joon-Shik Shin, Jinho Lee, In-Hyuk Ha

Long-Term Course of Failed Back Surgery Syndrome (FBSS) Patients Receiving Integrative Korean Medicine Treatment: A 1 Year Prospective Observational Multicenter Study

of Korean Medicine. Me-riong Kim and Areum Choi are employees of Jaseng Medical Foundation. Jinho Lee and In-Hyuk Ha are employees of Jaseng Hospital of Korean Medicine and Jaseng Medical Foundation ... for his help in statistical analysis. Author Contributions Conceptualization: Jinho Lee JSS YJL IHH. Data curation: ARC IHH. Formal analysis: IHH. Funding acquisition: Jun-Hwan Lee KMS BCS JHC IHH

Association between Knee Osteoarthritis, Cardiovascular Risk Factors, and the Framingham Risk Score in South Koreans: A Cross-Sectional Study

Background Osteoarthritis is a significant burden on personal health and for social cost, and its prevalence is rising. Recent research has revealed an association between osteoarthritis and cardiovascular disease, and this study uses the Framingham risk score (FRS), which is widely used as a composite index of cardiovascular risk factors, to investigate the association between...

Association between Hypertension and the Prevalence of Low Back Pain and Osteoarthritis in Koreans: A Cross-Sectional Study

Background Hypertension and musculoskeletal disorders are highly prevalent in adult populations. The objective of this study was to investigate the association between hypertension and prevalence of low back pain (LBP) and osteoarthritis in Koreans. Methods A total 17,128 participants (age ≥20 years) who answered low back pain and osteoarthritis items in the 4th Korean National...

Gender Difference in Associations between Chronic Temporomandibular Disorders and General Quality of Life in Koreans: A Cross-Sectional Study

Background Chronic temporomandibular disorder (TMD) is known to have strong correlations with psychological factors and to display gender disparity. However, while chronic TMD is known to affect quality of life, large-scale studies investigating the influence on quality of life by gender are scarce. Methods This cross-sectional study assessed the data of 17,198 participants aged...

The association between mental health, chronic disease and sleep duration in Koreans: a cross-sectional study

Background Sleep duration holds considerable importance as an indicator of mental/physical health. The objective of this study was to investigate the association between sleep duration, mental health, and chronic disease prevalence in Koreans. Methods Of 31,596 subjects eligible for the Korean National Health and Nutrition Examination Survey V (2010–2012), 17,638 participants who...

Effects of Shinbaro pharmacopuncture in sciatic pain patients with lumbar disc herniation: study protocol for a randomized controlled trial

Background Lumbar disc herniation is a major cause of sciatica and low back pain and imposes a heavy burden on both individual and society. While use of pharmacopuncture, a combined form of acupuncture and herbal medicine, for lumbar disc herniation is widespread in Korea and China, there is a paucity of research. Methods/Design This study is the protocol for a three-armed...

The Association between the History of Cardiovascular Diseases and Chronic Low Back Pain in South Koreans: A Cross-Sectional Study

Background Cardiovascular disease and related risk factors have been suggested as a mechanism leading to atherosclerosis of the lumbar vessels and consequent lumbar pain or sciatica. But there is continued controversy concerning its generalization. This study examined whether cardiovascular disease or its risk factors were associated with chronic low back pain (cLBP) in Koreans...

Identification of KMU-3, a Novel Derivative of Gallic Acid, as an Inhibitor of Adipogenesis

Differentiation of preadipocyte, also called adipogenesis, leads to the phenotype of mature adipocyte. Excessive adipogenesis, however, is largely linked to the development of obesity. Herein we investigated a library of 53 novel chemicals, generated from a number of polyphenolic natural compounds, on adipogenesis. Strikingly, among the chemicals tested, KMU-3, a derivative of...

A novel homozygous MPV17 mutation in two families with axonal sensorimotor polyneuropathy

Background Mutations in MPV17 cause the autosomal recessive disorder mitochondrial DNA depletion syndrome 6 (MTDPS6), also called Navajo neurohepatopathy (NNH). Clinical features of MTDPS6 is infantile onset of progressive liver failure with seldom development of progressive neurologic involvement. Methods Whole exome sequencing (WES) was performed to isolate the causative gene...

Unraveling the regulatory connections between two controllers of breast cancer cell fate

Estrogen receptor alpha (ERα) expression is critical for breast cancer classification, high ERα expression being associated with better prognosis. ERα levels strongly correlate with that of GATA binding protein 3 (GATA3), a major regulator of ERα expression. However, the mechanistic details of ERα–GATA3 regulation remain incompletely understood. Here we combine mathematical...

Overexpression of mutant HSP27 causes axonal neuropathy in mice

Background Mutations in heat shock 27 kDa protein 1 (HSP27 or HSPB1) cause distal hereditary motor neuropathy (dHMN) or Charcot-Marie-Tooth disease type 2 F (CMT2F) according to unknown factors. Mutant HSP27 proteins affect axonal transport by reducing acetylated tubulin. Results We generated a transgenic mouse model overexpressing HSP27-S135F mutant protein driven by...