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Tapentadol Extended Release in the Treatment of Severe Chronic Low Back Pain and Osteoarthritis Pain

responsibility for the integrity of the work as a whole, and have given their approval for this version to be published. Disclosures. Joseph V. Pergolizzi, Robert Taylor, Jr, Jo Ann LeQuang, Robert B. Raffa, and

The Basic Pharmacology of Opioids Informs the Opioid Discourse about Misuse and Abuse: A Review

Pergolizzi, Robert Raffa, Jo Ann LeQuang and Garrett Berger declare that they have no conflict of interest. Compliance with Ethics Guidelines. This article does not contain any new studies with human or