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Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation

by the Irish Health Research Board (#POR-2013-281). Joanna Cichy was supported by Polish National Science Center grant 2011/02/A/NZ5/00337. Michaela Pekarova was supported by the Ministry of Education

The Expression and Regulation of Chemerin in the Epidermis

Chemerin is a protein ligand for the G protein-coupled receptor CMKLR1 and also binds to two atypical heptahelical receptors, CCRL2 and GPR1. Chemerin is a leukocyte attractant, adipokine, and antimicrobial protein. Although chemerin was initially identified as a highly expressed gene in healthy skin keratinocytes that was downregulated during psoriasis, the regulation of...

Chemerin Is an Antimicrobial Agent in Human Epidermis

Cichy 0 Markus M. Heimesaat, Charite, Campus Benjamin Franklin, Germany 0 1 Department of Immunology, Faculty of Biochemistry , Biophysics and Biotechnology , Jagiellonian University , Krako w, Poland