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In vivo imaging of tumour xenografts with an antibody targeting the potassium channel Kv10.1

work was partly funded by the “Forschungsförderungprogramm 2011-Anschubfinanzierung I” of the University Medicine Göttingen to Joanna Napp. We thank Andrea Markus for proof-reading of the manuscript and

Optical imaging in vivo with a focus on paediatric disease: technical progress, current preclinical and clinical applications and future perspectives

Joanna Napp Julia E. Mathejczyk Frauke Alves 0 ) Department of Hematology and Oncology, University Medical Center Gttingen , Robert-Koch-Str. 40, 37075, Gttingen, Germany To obtain information on

The voltage dependence of hEag currents is not determined solely by membrane-spanning domains

The ether-à-go-go potassium channels hEag1 and hEag2 are highly homologous. Even though both possess identical voltage-sensing domain S4, the channels act differently in response to voltage. Therefore we asked whether transmembrane domains other than the voltage sensor could contribute to the voltage-dependent behaviour of these potassium channels. For this chimaeras were created, ...

Localization and Characterization of STRO-1+ Cells in the Deer Pedicle and Regenerating Antler

The annual regeneration of deer antlers is a unique developmental event in mammals, which as a rule possess only a very limited capacity to regenerate lost appendages. Studying antler regeneration can therefore provide a deeper insight into the mechanisms that prevent limb regeneration in humans and other mammals, and, with regard to medical treatments, may possibly even show ways ...