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Seasonal changes in objectively measured sedentary behavior and physical activity in Japanese primary school children

Background The recent prevalence of obesity in Japanese children is much higher compared to 1980. The present study compared daily sedentary behavior (SB) and physical activity (PA) between the school year and summer vacation in Japanese primary school children. Methods Participants were 98 Japanese boys (8.9 ± 1.8 years at baseline) and 111 girls (9.1 ± 1.8 years). SB and PA...

Development of sedentary behavior across childhood and adolescence: longitudinal analysis of the Gateshead Millennium Study

Background In many parts of the world policy and research interventions to modify sedentary behavior of children and adolescents are now being developed. However, the evidence to inform these interventions (e.g. how sedentary behavior changes across childhood and adolescence) is limited. This study aimed to assess longitudinal changes in sedentary behavior, and examine the degree...

Projections of Water Stress Based on an Ensemble of Socioeconomic Growth and Climate Change Scenarios: A Case Study in Asia

The sustainability of future water resources is of paramount importance and is affected by many factors, including population, wealth and climate. Inherent in current methods to estimate these factors in the future is the uncertainty of their prediction. In this study, we integrate a large ensemble of scenarios—internally consistent across economics, emissions, climate, and...

Neutropenic sepsis is associated with distinct clinical and biological characteristics: a cohort study of severe sepsis

Background Immunocompromised patients who develop sepsis while neutropenic are at high risk for morbidity and mortality; however, it is unknown if neutropenic sepsis is associated with distinct clinical and biological characteristics. Methods We conducted a prospective cohort study of patients admitted to the medical intensive care unit of an academic medical center with severe...

Integrated economic and climate projections for impact assessment

Sergey Paltsev Erwan Monier Jeffery Scott Andrei Sokolov John Reilly We designed scenarios for impact assessment that explicitly address policy choices and uncertainty in climate response. Economic

Objective measurement of sedentary behavior: impact of non-wear time rules on changes in sedentary time

Background Accelerometry non-wear time rules might affect sedentary time, and the associations with health outcomes such as adiposity. However, the exact effect of different non-wear time rules on sedentary time and reported changes in sedentary time is unknown. This study evaluated the effect of different accelerometry non-wear time rules on sedentary time and changes in...

Increasing physical activity among young children from disadvantaged communities: study protocol of a group randomised controlled effectiveness trial

Background Participation in regular physical activity (PA) during the early years helps children achieve healthy body weight and can substantially improve motor development, bone health, psychosocial health and cognitive development. Despite common assumptions that young children are naturally active, evidence shows that they are insufficiently active for health and developmental...

Low Plasma Levels of Adiponectin Do Not Explain Acute Respiratory Distress Syndrome Risk: a Prospective Cohort Study of Patients with Severe Sepsis

Background Obesity is associated with the development of acute respiratory distress syndrome (ARDS) in at-risk patients. Low plasma levels of adiponectin, a circulating hormone-like molecule, have been implicated as a possible mechanism for this association. The objective of this study was to determine the association of plasma adiponectin level at ICU admission with ARDS and 30...

Objectively measured physical activity and sedentary time in youth: the International children’s accelerometry database (ICAD)

Background Physical activity and sedentary behaviour in youth have been reported to vary by sex, age, weight status and country. However, supporting data are often self-reported and/or do not encompass a wide range of ages or geographical locations. This study aimed to describe objectively-measured physical activity and sedentary time patterns in youth. Methods The International...

Long-term Comparative Immunogenicity of Protein Conjugate and Free Polysaccharide Pneumococcal Vaccines in Chronic Obstructive Pulmonary Disease

Background. Although the 23-valent pneumococcal polysaccharide vaccine (PPSV23) protects against invasive disease in young healthy persons, randomized controlled trials in chronic obstructive pulmonary disease (COPD) have demonstrated no benefit in the intention-to-treat population. We previously reported that the 7-valent diphtheria-conjugated pneumococcal polysaccharide vaccine...

18th European Symposium on Radiopharmacy and Radiopharmaceuticals

, Yves P. Auberson, John Reilly, Mark Healy, David Sykes OP23 The radiosynthesis of an 18F-labeled triglyceride, developed to visualize and quantify brown adipose tissue activity Andreas Paulus, Wouter van