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17 papers found.
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Intensified hand-hygiene campaign including soap-and-water wash may prevent acute infections in office workers, as shown by a recognized-exposure -adjusted analysis of a randomized trial

analysis of a randomized trial Tapani Hovi 0 Jukka Ollgren 0 Carita Savolainen-Kopra 0 0 Department of Infectious Diseases, Viral Infections Unit, National Institute for Health and Welfare (THL) , P.O. Box

Development of a prognostic model based on demographic, environmental and lifestyle information for predicting incidences of symptomatic respiratory or gastrointestinal infection in adult office workers

Background Occurrence of respiratory tract infection (RTI) or gastrointestinal tract infection (GTI) is known to vary between individuals and may be a confounding factor in the analysis of the results of intervention trials. We aimed at developing a prognostic model for predicting individual incidences of RTI and GTI on the basis of data collected in a hand-hygiene intervention ...

Genomic Characteristics Behind the Spread of Bacteremic Group A Streptococcus Type emm89 in Finland, 2004–2014

Background. Many countries worldwide have reported increasing numbers of emm89 group A Streptococcus (GAS) infections during last decade. Pathogen genetic factors linked to this increase need assessment. Methods. We investigated epidemiological characteristics of emm89 GAS bacteremic infections, including 7-day and 30-day case-fatality rates, in Finland during 2004–2014 and linked ...

Evaluation of the Intussusception Risk after Pentavalent Rotavirus Vaccination in Finnish Infants

Background An association between rotavirus immunisation and intussusception (IS) has been suggested with present rotavirus vaccines in post-licensure studies. In Finland, rotavirus vaccination programme was implemented in September 2009 using a 2, 3, and 5 months schedule with the pentavalent rotavirus vaccine. By the end of 2013, it is estimated that 719 000 rotavirus vaccine ...

Exposure to persons with symptoms of respiratory or gastrointestinal infection and relative risk of disease: self-reported observations by controls in a randomized intervention trial

Background Little is known about the quantitative relationships between a self-recognized exposure to people with symptoms of respiratory (RTI) or gastrointestinal tract infection (GTI) and subsequent occurrence of homologous symptoms in the exposed person. Methods Adult office employees, controls in an intervention trial, reported weekly own symptoms of RTI or GTI and exposures to ...

Antimicrobials Increase Travelers' Risk of Colonization by Extended-Spectrum Betalactamase-Producing Enterobacteriaceae

. Pakkanen 0 Jukka Ollgren 3 Jenni Antikainen 4 Juha Kirveskari 4 0 Department of Bacteriology and Immunology, University of Helsinki 1 Division of Infectious Diseases, Department of Medicine, Helsinki

Estimating the burden of healthcare-associated infections caused by selected multidrug-resistant bacteria Finland, 2010

Background Knowledge of the burden of healthcare-associated infections (HAI) and antibiotic resistance is important for resource allocation in infection control. Although national surveillance networks do not routinely cover all HAIs due to multidrug-resistant bacteria, estimates are nevertheless possible: in the EU, 25,000 patients die from such infections annually. We assessed ...

Agricultural, socioeconomic and environmental variables as risks for human verotoxigenic Escherichia coli (VTEC) infection in Finland

Background Verotoxigenic E. coli (VTEC) is the cause of severe gastrointestinal infection especially among infants. Between 10 and 20 cases are reported annually to the National Infectious Disease Register (NIDR) in Finland. The aim of this study was to identify explanatory variables for VTEC infections reported to the NIDR in Finland between 1997 and 2006. We applied a hurdle ...

Treatment outcome of extra-pulmonary tuberculosis in Finland: a cohort study

Background We investigated the treatments given, the outcome and the patient- and treatment-system dependent factors affecting treatment outcome in a national two-year cohort of culture-verified extra-pulmonary tuberculosis cases in Finland. Methods Medical records of all cases in 1995 - 1996 were abstracted to assess treatment and outcome, using the European recommendations for ...

Novel Microbiological and Spatial Statistical Methods to Improve Strength of Epidemiological Evidence in a Community-Wide Waterborne Outbreak

Failures in the drinking water distribution system cause gastrointestinal outbreaks with multiple pathogens. A water distribution pipe breakage caused a community-wide waterborne outbreak in Vuorela, Finland, July 2012. We investigated this outbreak with advanced epidemiological and microbiological methods. A total of 473/2931 inhabitants (16%) responded to a web-based ...

Epidemic Sindbis Virus Infection in Finland: A Population-Based Case-Control Study of Risk Factors

Background. Sindbis virus (SINV) is an arthropod-borne alphavirus that causes rash and arthritis. In Finland, epidemics occur cyclically, but factors associated with clinical SINV infection are largely unknown. We conducted a population-based case-control study during the epidemic year 2002. Methods. SINV cases were serologically confirmed and reported to the National Infectious ...

Epidemiological Evidence for Serotype‐Independent Acquired Immunity to Pneumococcal Carriage

Background. Asymptomatic nasopharyngeal carriage is the main reservoir for transmission of Streptococcus pneumoniae. The rate of both carriage and pneumococcal disease decreases with age. To what extent these changes are the result of developing natural immunity is currently a subject of debate. Objective. To study the hypothesis that previous carriage induces serotype‐independent ...

Invasive pneumococcal infections among persons with and without underlying medical conditions: Implications for prevention strategies

Background The 23-valent pneumococcal polysaccharide vaccine (PPV23) is recommended for persons aged < 65 years with chronic medical conditions. We evaluated the risk and mortality from invasive pneumococcal disease (IPD) among persons with and without the underlying medical conditions which are considered PPV23 indications. Methods Population-based data on all episodes of IPD ...

Risk factors for poor tuberculosis treatment outcome in Finland: a cohort study

Background We investigated the patient- and treatment-system dependent factors affecting treatment outcome in a two-year cohort of all treated culture-verified pulmonary tuberculosis (TB) cases to establish a basis for improving outcomes. Methods Medical records of all cases in 1995 – 1996 were abstracted to assess outcome of treatment. Outcome was divided into three groups: ...

FIELD EVALUATION OF THE CHESSBOARD MODIFICATION FOR SEROTYPING OF STREPTOCOCCUS PNEUMONIAE IN A SMALL LABORATORY IN BANGLADESH

interests. Authors addresses: Elja Herva, National Public Health Institute, Box 310 FIN-90101, Oulu, Finland, Telephone: 358-8-537-6210, Fax: 358-8-537-6251, E-mail: . Simo Granat, Jukka Ollgren, Liisa

An Outbreak of Gastrointestinal Illness and Erythema Nodosum from Grated Carrots Contaminated with Yersinia pseudotuberculosis

BackgroundOutbreaks of Yersinia pseudotuberculosis infection have been epidemiologically linked to fresh produce, but the bacterium has not been recovered from the food items implicated. In May 2003, a cluster of gastrointestinal illness and erythema nodosum was detected among schoolchildren who had eaten lunches prepared by the same institutional kitchen MethodsWe conducted a ...

Functional Antibodies Elicited by an 11-Valent Diphtheria-Tetanus Toxoid-Conjugated Pneumococcal Vaccine

The aluminium-adjuvanted 11-valent pneumococcal conjugate vaccine containing polysaccharides 1, 4, 5, 7F, 9V, 19F, and 23F (coupled to tetanus protein) and polysaccharides 3, 6B, 14, and 18C (coupled to diphtheria toxoid) elicits high antibody concentrations in Filipino infants when given at ages 6, 10, and 14 weeks and 9 months simultaneously with the national vaccination program. ...