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Strategies for the Use of Oseltamivir and Zanamivir during Pandemic Outbreaks

zanamivir during pandemic outbreaks Elsa Hansen MEng Troy Day Julien Arino Jianhong Wu Seyed M Moghadas Antiviral treatment; Drug resistance; Epidemic modelling; Pandemic influenza - BACkgrounD: The use ... during Pandemic Outbreaks Elsa Hansen, Troy Day, Julien Arino, Jianhong Wu, Seyed M. Moghadas This appendix provides details of the model structure with additional simulations that were performed to test

Strategies for the Use of Oseltamivir and Zanamivir during Pandemic Outbreaks

zanamivir during pandemic outbreaks Elsa Hansen MEng Troy Day Julien Arino Jianhong Wu Seyed M Moghadas Antiviral treatment; Drug resistance; Epidemic modelling; Pandemic influenza - BACkgrounD: The use ... during Pandemic Outbreaks Elsa Hansen, Troy Day, Julien Arino, Jianhong Wu, Seyed M. Moghadas This appendix provides details of the model structure with additional simulations that were performed to test

Strategies for the Use of Oseltamivir and Zanamivir during Pandemic Outbreaks

zanamivir during pandemic outbreaks Elsa Hansen MEng Troy Day Julien Arino Jianhong Wu Seyed M Moghadas Antiviral treatment; Drug resistance; Epidemic modelling; Pandemic influenza - BACkgrounD: The use ... during Pandemic Outbreaks Elsa Hansen, Troy Day, Julien Arino, Jianhong Wu, Seyed M. Moghadas This appendix provides details of the model structure with additional simulations that were performed to test

Quantifying the annual incidence and underestimation of seasonal influenza: A modelling approach

Manitoba, Department of Mathematics, Winnipeg, R3T 2N2, MB, Canada Julien Arino Leslie Dan School of Pharmacy, University of Toronto, Toronto, M5S 3M2, ON, Canada Ayman Chit Sanofi Pasteur, Swiftwater ... Scholar Julien Arino View author publications You can also search for this author in PubMed Google Scholar Jane Heffernan View author publications You can also search for this author in PubMed

Antiviral resistance during pandemic influenza: implications for stockpiling and drug use

Background The anticipated extent of antiviral use during an influenza pandemic can have adverse consequences for the development of drug resistance and rationing of limited stockpiles. The strategic use of drugs is therefore a major public health concern in planning for effective pandemic responses. Methods We employed a mathematical model that includes both sensitive and...

Antiviral resistance during pandemic influenza: implications for stockpiling and drug use

The anticipated extent of antiviral use during an influenza pandemic can have adverse consequences for the development of drug resistance and rationing of limited stockpiles. The strategic use of drugs is therefore a major public health concern in planning for effective pandemic responses. We employed a mathematical model that includes both sensitive and resistant strains of a...

Simple models for containment of a pandemic

Stochastic simulations of network models have become the standard approach to studying epidemics. We show that many of the predictions of these models can also be obtained from simple classical deterministic compartmental models. We suggest that simple models may be a better way to plan for a threatening pandemic with location and parameters as yet unknown, reserving more...