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137 papers found.
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HbA1c is Positively Associated with Serum Carcinoembryonic Antigen (CEA) in Patients with Diabetes: A Cross-Sectional Study

, take responsibility for the integrity of the work as a whole, and have given final approval for the version to be published. Author Contributions. Jun Lu performed the statistical analysis and wrote the ... manuscript; Hongtao Wang collected data, Xueli Zhang and Xuemei Yu participated in the design of this study and edited the manuscript. Disclosures. Jun Lu, Hongtao Wang, Xueli Zhang, and Xuemei Yu have

Preventive behaviors adults report using to avoid catching or spreading influenza, United States, 2015-16 influenza season

curation: Anup Srivastav, Tammy A. Santibanez. Formal analysis: Anup Srivastav, Tammy A. Santibanez, Peng-Jun Lu, Jill A. Dever, Michael Bostwick, Marshica Stanley Kurtz. Funding acquisition: Walter W ... . Williams. Investigation: Anup Srivastav, Tammy A. Santibanez, Peng-Jun Lu, M. Christopher Stringer, Jill A. Dever, Michael Bostwick, Marshica Stanley Kurtz, Walter W. Williams. Methodology: Anup Srivastav

Effect of overexpression of LPAAT and GPD1 on lipid synthesis and composition in green microalga Chlamydomonas reinhardtii

Biodiesel is an alternative energy source which has attracted increasing attention lately. Although algae-based biodiesel production has many benefits, it is still far from industrial application. Research suggests that improving lipid quality and production through genetic engineering of metabolic pathways will be the most promising way. To enhance lipid content, both...

MicroRNAs in Control of Stem Cells in Normal and Malignant Hematopoiesis

establishing key principles. Compliance with Ethical Standards Conflict of Interest no conflict of interest. Christine Roden and Jun Lu declare that they have Human and Animal Rights and Informed Consent

Numerical study on the lubrication performance of compression ring-cylinder liner system with spherical dimples

compression ring crown height and axial width have less effect on the power loss reduction. Author Contributions Conceptualization: Cheng Liu, Yan-Jun Lu, Yong-Fang Zhang, Sha Li. Data curation: Cheng Liu ... , Yan-Jun Lu, Sha Li. Formal analysis: Cheng Liu, Yan-Jun Lu, Yong-Fang Zhang, Sha Li. Investigation: Cheng Liu, Yan-Jun Lu. Methodology: Cheng Liu, Yan-Jun Lu, Yong-Fang Zhang. Project administration

CHOP favors endoplasmic reticulum stress-induced apoptosis in hepatocellular carcinoma cells via inhibition of autophagy

. Methodology: Bingshuang Ren, Shihuai Zhan, Yunfeng Fu. Software: Jun Lu. Supervision: Lianghu Huang, Jianming Tan. Writing ± original draft: Jin Wang. Writing ± review & editing: Shuiliang Wang. 15 / 17 16

Effects of canagliflozin on weight loss in high-fat diet-induced obese mice

Canagliflozin, an inhibitor of sodium glucose co-transporter (SGLT) 2, has been shown to reduce body weight during the treatment of type 2 diabetes mellitus (T2DM). In this study, we sought to determine the role of canagliflozin in body weight loss and liver injury in obesity. C57BL/6J mice were fed a high-fat diet to simulate diet-induced obesity (DIO). Canagliflozin (15 and 60...

The morphological regeneration and functional restoration of bladder defects by a novel scaffold and adipose-derived stem cells in a rat augmentation model

Background Due to the multilineage differentiation ability and paracrine role of adipose-derived stem cells (ASCs) for bladder defect repair, various scaffolds have been applied in combination with ASCs to promote bladder regeneration and restore bladder function. However, the low survival rate of ASCs and the difficulty of promoting bladder functional recovery are still unsolved...

Health Disparities by Type of Disability: Health Examination Results of Adults (18-64 Years) with Disabilities in Shanghai, China

Aims There have been few studies on the disparities within the population with disabilities, especially in China. The aim of this study was to evaluate the differences in some health conditions among people with different types of disabilities in Shanghai. Methods This study was conducted using data from the Shanghai Disabled Persons’ Rehabilitation Comprehensive Information...

Effects of Land Use, Topography and Socio-Economic Factors on River Water Quality in a Mountainous Watershed with Intensive Agricultural Production in East China

Understanding the primary effects of anthropogenic activities and natural factors on river water quality is important in the study and efficient management of water resources. In this study, analysis of Variance (ANOVA), Principal component analysis (PCA), Pearson correlations, Multiple regression analysis (MRA) and Redundancy analysis (RDA) were applied as an integrated approach...

Design and Hardware Implementation of a New Chaotic Secure Communication Technique

In this paper, a scheme for chaotic modulation secure communication is proposed based on chaotic synchronization of an improved Lorenz system. For the first time, the intensity limit and stability of the transmitted signal, the characteristics of broadband and the requirements for accuracy of electronic components are presented by Multisim simulation. In addition, some...

The combination of herbal medicine Weng-li-tong with Tolterodine may be better than Tolterodine alone in the treatment of overactive bladder in women: a randomized placebo-controlled prospective trial

Background To assess the efficacy and safety of the herbal medicine, Weng-li-tong (WLT) as monotherapy or combined with tolterodine in women with overactive bladder (OAB). Methods A prospective, randomized, single-blind multi-center trial was performed which included 182 OAB patients treated with either placebo (n = 26), WLT (n = 52), tolterodine (n = 52) or WLT plus tolterodine...

ClpP-deletion impairs the virulence of Legionella pneumophila and the optimal translocation of effector proteins

Yong-jun Lu 1 0 Equal contributors 1 School of Life Sciences and Biomedical Center, Sun Yat-sen University , No. 135 Xingang road west, Guangzhou 510275 , China 2 Present address: School of Life Sciences ... . 30970123) and the Natural Science Foundation of Guangdong province (No. 2016A030311036) to Yong-jun Lu. Availability of data and materials All data generated or analyzed during this study are included in

DSSR: an integrated software tool for dissecting the spatial structure of RNA

Insight into the three-dimensional architecture of RNA is essential for understanding its cellular functions. However, even the classic transfer RNA structure contains features that are overlooked by existing bioinformatics tools. Here we present DSSR (Dissecting the Spatial Structure of RNA), an integrated and automated tool for analyzing and annotating RNA tertiary structures...

Electrohydrodynamic Drying of Carrot Slices

Carrots have one of the highest levels of carotene, and they are rich in vitamins, fiber and minerals. However, since fresh carrots wilt rapidly after harvest under inappropriate storage conditions, drying has been used to improve their shelf life and retain nutritional quality. Therefore, to further investigate the potential of this method, carrot slices were dried in an EHD...

Long-term clinical and echocardiographic outcomes of extensive septal myectomy for hypertrophic obstructive cardiomyopathy in Chinese patients

Background There has been limited data addressing outcomes of extensive septal myectomy in Chinese patients with hypertrophic obstructive cardiomyopathy (HOCM). In this study, the objective was to evaluate the clinical and echocardiographic outcomes of extensive septal myectomy in a relative large number of Chinese HOCM patients over long-term follow-up. Methods We...

Childhood mitochondrial encephalomyopathies: clinical course, diagnosis, neuroimaging findings, mtDNA mutations and outcome in six children

Mitochondrial dysfunction manifests in many forms during childhood. There is no effective therapy for the condition; hence symptomatic therapy is the only option. The effect of symptomatic therapy are not well known. We present clinical course, diagnosis and effect of current treatments for six children suffering from mitochondrial encephalomyopathy identified by clinical...

Integrative epigenomic analysis reveals unique epigenetic signatures involved in unipotency of mouse female germline stem cells

Background Germline stem cells play an essential role in establishing the fertility of an organism. Although extensively characterized, the regulatory mechanisms that govern the fundamental properties of mammalian female germline stem cells remain poorly understood. Results We generate genome-wide profiles of the histone modifications H3K4me1, H3K27ac, H3K4me3, and H3K27me3, DNA...

An evaluation of China’s new rural cooperative medical system: achievements and inadequacies from policy goals

Background Although much public scrutiny and academic attention has focused on the evaluations of system implementation since the beginning of New Rural Cooperative Medical System (NRCMS) in China, few studies have systematically evaluated the achievements of the stated policy goals. The purpose of this study is to examine to what extent the policy goals of NRCMS have been...

Cadherin-12 enhances proliferation in colorectal cancer cells and increases progression by promoting EMT

Cadherin-12 (CDH12) is a subtype of N-cadherin family. In this study, we investigated the expression of CDH12 and the role of CDH12 in prognosis of colorectal cancer (CRC) patients. In addition, we observed the influence of CDH12 on proliferation and progression of CRC cell lines. By using immunohistochemical staining, we analyzed CRC samples and adjacent non-tumor tissues...