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17 papers found.
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Value of adding the renal pathological score to the kidney failure risk equation in advanced diabetic nephropathy

manuscript. Author Contributions Conceptualization: Takashi Wada. Data curation: Junichi Hoshino, Keiichi Kinowaki, Takeshi Fujii, Kenichi Ohashi, Koki Mise, Tadashi Toyama, Akinori Hara, Kiyoki Kitagawa ... , Miho Shimizu, Kengo Furuichi. Formal analysis: Masayuki Yamanouchi, Junichi Hoshino. Investigation: Masayuki Yamanouchi. Methodology: Masayuki Yamanouchi, Junichi Hoshino, Kengo Furuichi. Project

Paratubular basement membrane insudative lesions predict renal prognosis in patients with type 2 diabetes and biopsy-proven diabetic nephropathy

, Yoshifumi Ubara. Data curation: Koki Mise, Junichi Hoshino, Toshiharu Ueno, Akinari Sekine, Keiichi Sumida, Masayuki Yamanouchi, Noriko Hayami, Tatsuya Suwabe, Rikako Hiramatsu, Eiko Hasegawa, Naoki Sawa ... , Takeshi Fujii, Shigeko Hara, Kenichi Ohashi, Yoshifumi Ubara. Formal analysis: Koki Mise, Junichi Hoshino, Kenichi Ohashi. 14 / 16 Investigation: Koki Mise, Yutaka Yamaguchi, Toshiharu Ueno, Akinari Sekine

Intracystic magnetic resonance imaging in patients with autosomal dominant polycystic kidney disease: features of severe cyst infection in a case–control study

Background The purpose of this study was to investigate the usefulness of intracystic MRI features for detection of severe cyst infection that is usually refractory to antibiotic therapy alone in patients with autosomal dominant polycystic kidney disease. Methods Seventy-six patients (88 episodes) with positive cyst cultures treated from January 2006 to December 2013 were enrolled ...

Evidence-based clinical practice guidelines for nephrotic syndrome 2014

Sasatomi, Yoshinobu Sato, Tomoya Nishino, Kazuhiko Tsuruya, Kengo Furuichi, Junichi Hoshino, Yasuhiro Watanabe. Chief Chairman of the Clinical Practice Guidelines for Progressive Kidney Diseases: Kenjiro

Effect of Proteinuria and Glomerular Filtration Rate on Renal Outcome in Patients with Biopsy-Proven Benign Nephrosclerosis

Background Reduced estimated glomerular filtration rate (eGFR) and proteinuria are risk factors for end-stage renal disease (ESRD), of which benign nephrosclerosis is a common cause. However, few biopsy-based studies have assessed these associations. Methods We performed retrospective cohort study of 182 Japanese patients who underwent renal biopsy from June 1985 through March 2014 ...

Renal prognosis a long time after renal biopsy on patients with diabetic nephropathy

Background A new classification of diabetic nephropathy was reported by Tervaert et al., but the association between pathological findings and the clinical outcomes remains unclear.

Developing an HbA1c-Based Equation to Estimate Blood Glucose in Maintenance Hemodialysis Patients

JUNICHI HOSHINO MIKLOS Z. MOLNAR PHD KUNIHIRO YAMAGATA PHD YOSHIFUMI UBARA PHD KENMEI TAKAICHI PHD CSABA P. KOVESDY KAMYAR KALANTAR-ZADEH PHD E p i d e m i o l o g y / H e a l t h

Quality of life of patients with ADPKD—Toranomon PKD QOL study: cross-sectional study

Background The quality of life (QOL) of patients with autosomal dominant polycystic kidney disease (ADPKD) has not been investigated well. This study was performed to clarify the QOL of patients with ADPKD and to identify factors that affected their QOL. Methods The present cross-sectional study is part of a prospective observational study on the QOL of ADPKD patients. Patients ...

Membranoproliferative glomerulonephritis and circulating cryoglobulins

Background Previous studies on membranoproliferative glomerulonephritis (MPGN) and cryoglobulinemic glomerulopathy (CG) were based upon case series that were performed before hepatitis C virus (HCV) infection was routinely investigated. Therefore, it remains unknown how far HCV contributes to MPGN or CG, and there have only been a few reports about HCV-negative idiopathic MPGN. ...

Myeloperoxidase-antineutrophil cytoplasmic antibody-associated crescentic glomerulonephritis in autosomal dominant polycystic kidney disease

Background Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disorder that is characterized by the development of cysts in the kidneys and other organs. Urinary protein excretion is usually less than 1 g/day, and ADPKD is rarely associated with nephrotic syndrome or rapidly progressive glomerulonephritis (RPGN). To date, myeloperoxidase (MPO)-antineutrophil ...

Association of Pretransplant Glycemic Control With Posttransplant Outcomes in Diabetic Kidney Transplant Recipients

OBJECTIVE Observational studies have yielded inconsistent findings regarding the association of hemoglobin A1c (HbA1c) with survival in diabetic patients on dialysis. The association between pretransplant glycemic control and short- and long-term posttransplant outcomes in kidney transplant recipients is not clear.

Long term follow up of congenital thrombotic thrombocytopenic purpura (Upshaw-Schulman syndrome) on hemodialysis for 19 years: a case report

Background Thrombotic thrombocytopenic purpura (TTP) is frequently associated with renal abnormalities, but there have been few reports about renal abnormalities in patients with hereditary TTP. In particular, little is known about the long-term prognosis of patients with childhood-onset congenital TTP. Case presentation We report a Japanese patient with congenital TTP ...

Estimated glomerular filtration rate at reinitiation of dialysis and mortality in failed kidney transplant recipients

Background Recent observational studies and a controlled trial suggest more favorable outcomes upon later dialysis initiation in chronic kidney disease. The role of estimated glomerular filtration rate (eGFR) in predicting outcome at reinitiation of dialysis in failed kidney transplant recipients is unclear.

DIALYSIS BONE DISEASE

Introduction and Aims: Vertebral Fractures (VFs) are common in the general population and in Chronic Kidney Disease patients. VFs are associated with vascular calcifications (VCs) and to an increased risk of mortality. The Spine Deformity Index (SDI) is a summary measure of the VFs status, incorporating both the number and severity of VFs in a score. The aim of this study was to ...

PRIMARY AND SECONDARY GLOMERULONEPHRITIDES 1

Introduction and Aims: Loss of podocytes in primary glomerulopathies is crucial for glomerulosclerosis progression which leads to end-stage renal failure in such patients. The mechanism of direct replacement of injured podocytes does not exist so the only way to compensate the integrity of glomerulus is change of cells shape to cover the glomerular tuft with a smaller number of ...

CKD PATHOPHYSIOLOGY AND CLINICAL STUDIES

Introduction and Aims: Patients with chronic kidney disaeses (CKD) suffer from accelered vascular calcification (VC) and vitamin K defficiency. The vitamin K-dependent matrix Gla protein (MGP) is one of the most powerful inhibitors of VC. This prospective randomized intervention study assessed the impact of vitamin K2 supplementation on levels of the inactive form of MGP ...