Wangsheng Ji 0 Junqi Zhang 0 Jing Lu 0 Xinqi Liu 0 State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University , Tianjin , China Edited by T. Brunner T cell homeostasis
This study employs fluorescence spectroscopy to characterize the binding properties of a newly synthesized cardiac agent, V-09, on bovine serum albumin (BSA). This compound shows the highest cardiac activity in the whole series. The binding constants K at 25°C and 37°C are obtained, the values are 7.12×104 l mol–1, 4.66×104 l mol–1, respectively. The standard enthalpy change (ΔH0...
and Guangfei Wang. Disclosures. Qiaofeng Ye, Guangfei Wang, Yidie Huang, Jinmiao Lu, Junqi Zhang, Lin Zhu, Yiqing Zhu, Xiaoxia Li, Jianger Lan, Ziwei Li, Yubing Liu, Hong Xu and Zhiping Li have nothing ... , Guangfei Wang, and Zhiping Li; Methodology: Qiaofeng Ye, Guangfei Wang, Yidie Huang, Jinmiao Lu, and Xiaoxia Li; Formal analysis and investigation: Qiaofeng Ye, Guangfei Wang, Yidie Huang, Jinmiao Lu, Junqi
This study employs fluorescence spectroscopy to characterize the binding properties of a newly synthesized cardiac agent, V-09, on bovine serum albumin (BSA). This compound shows the highest cardiac activity in the whole series. The binding constants K at 25°C and 37°C are obtained, the values are 7.12×104 l mol–1, 4.66×104 l mol–1, respectively. The standard enthalpy change (ΔH0...
This study employs fluorescence spectroscopy to characterize the binding properties of a newly synthesized cardiac agent, V-09, on bovine serum albumin (BSA). This compound shows the highest cardiac activity in the whole series. The binding constants K at 25°C and 37°C are obtained, the values are 7.12×104 l mol–1, 4.66×104 l mol–1, respectively. The standard enthalpy change (ΔH0...
approved publication: Dr Mian Wang Yinxing Shen,1,2 Mengya Li,1 Tianqi Liu,1 Jing Liu,2 Youhua Xie,2 Junqi Zhang,2 Shouhong Xu,1 Honglai Liu1 1Key Laboratory for Advanced Materials
There has been increasing interest in the construction of liposomes containing a targeting reagent for target-specific drug delivery. Glycoconjugates that can be recognized by transmembrane glycoprotein receptors have been extensively used to form glyco-liposomal drug carriers. However, the impact of anomerism, which is a common identity of natural glycoconjugates, on the glyco...
Copolymer micelles function as pH-responsive nanocarriers to enhance the cytotoxicity of a HER2 aptamer in HER2-positive breast cancer cells Yinxing Shen,1,2,* Junqi Zhang,2,* Weiju Hao,1 Tong Wang,1
Prince Rupprecht's larch (Larix principis-rupprechtii Mayr) is a native high-value forest tree species in North China whose clonal propagation through somatic embryogenesis (SE) has the potential to rapidly capture the benefits of breeding or genetic engineering programs and to improve raw material uniformity and quality. To date, research has focused on clarifying the molecular...
, Yanfeng Liu, Junqi Zhang, Jiming Zhang, Youhua Xie & Jing LiuDepartment of Infectious Diseases, Huashan Hospital, Fudan University, 12 Middle Wulumuqi Road, 200040, Shanghai, People’s Republic of ... Yanfeng Liu in:Nature Research journals • PubMed • Google Scholar Search for Junqi Zhang in:Nature Research journals • PubMed • Google Scholar Search for Jiming Zhang in:Nature Research journals • PubMed
Primary duck hepatocytes (PDH) displays differential susceptibility to duck hepatitis B virus when maintained in the media supplemented with fetal bovine serum or dimethyl sulfoxide (DMSO) which has been widely used for the maintenance of hepatocytes, and prolonging susceptibility to hepadnavirus. However the mechanism underlying maintenance of susceptibility to hepadnavirus by...
Background Shigella is a major pathogen responsible for bacillary dysentery, a severe form of shigellosis. Severity of the disease depends on the virulence of the infecting strain. Shigella pathogenicity is a multi-gene phenomenon, involving the participation of genes on an unstable large virulence plasmid and chromosomal pathogenicity islands. Results A multiplex PCR (mPCR...
Entry inhibitors are promising novel antivirals against hepatitis B virus (HBV) infection. The existing potential entry inhibitors have targeted the cellular receptor(s). In this study, we aim to develop the first entry inhibitor that inhibits HBV infection via targeting viral particles. The preS1 segment of the large envelope glycoprotein of HBV is essential for virion...
A sensitive DNA isothermal amplification method for the detection of DNA at fM to aM concentrations for pathogen identification was developed using a non-stick-coated metal microfluidic bioreactor. A portable confocal optical detector was utilized to monitor the DNA amplification in micro- to nanoliter reaction assays in real-time, with fluorescence collection near the optical...