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Chronic restraint stress induces excessive activation of primordial follicles in mice ovaries

. (DOC) Author Contributions Conceptualization: Chunsheng Wei, Dongmei Lai. Data curation: Junyan Sun. Formal analysis: Chunsheng Wei, Dongmei Lai. Funding acquisition: Dongmei Lai. Investigation ... : Minhua Xu, Junyan Sun, Qiuwan Zhang. Methodology: Minhua Xu, Junyan Sun, Qian Wang, Qiuwan Zhang. Project administration: Minhua Xu, Junyan Sun, Qian Wang, Chunsheng Wei, Dongmei Lai. Resources: Dongmei

Paracrine effects of human amniotic epithelial cells protect against chemotherapy-induced ovarian damage

Background Human amniotic epithelial cells (hAECs) are attractive candidates for regenerative medical therapy, with the potential to replace deficient cells and improve functional recovery after injury. Previous studies have demonstrated that transplantation of hAECs effectively alleviate chemotherapy-induced ovarian damage via inhibiting granulose cells apoptosis in animal...

A Standardized Precipitation Evapotranspiration Index Reconstruction in the Taihe Mountains Using Tree-Ring Widths for the Last 283 Years

Tree-ring samples from Chinese Pine (Pinus tabulaeformis Carr.) that were collected in the Taihe Mountains on the western Loess Plateau, China, were used to analyze the effects of climate and drought on radial growth and to reconstruct the mean April-June Standardized Precipitation Evapotranspiration Index (SPEI) during the period 1730–2012 AD. Precipitation positively affected...