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Abstracts from the 2012 BNOS Conference

BY HYPERMETHYLATION IN PAEDIATRIC EPENDYMOMA K Karakoula, KP Phipps, W Harkness, R Hayward, D Thompson, TS Jacques, B Harding, J Darling, and T Warr; Brain Tumour UK Neuro-Oncology Research Centre

Chromosome analysis of bovine oocytes cultured in vitro

, Desjardin M, Xu KP, Bousquet D (1990) Chromosome analysis of horse oocytes in vitro. Genet Sel Evol 22, 151-160 Krallinger HF (1927) Uber die Chromosomenzahl beim Rind sowie einige allgemeine Bemerkungen uber

A 16S rDNA-based molecular profiling approach for studying relative changes in ruminal bacterial populations

ecological studies. SH DD1,uunnccana’n KP Scott CS Stewart HJ F1lint F T2hompson-Carter TH 2Yennington (’Rowett Research Institute, Bucksburn, Aberdeen AB2l 9SB, U;K D2epartment of Medical Microbiology ... . Stahl DA , Flesher B , Mansfield HR , Montgomery L ( 1988 ) Appl Environ Microbiol 54 , 1079 - 1084 2. Wood J , Avgustin G , Scott KP , Flint HJ ( 1995 ) In: Beijerinck Centennial, Abstracts Book, The

A novel mobile chromosomal element conferring TcR in rumen Butyrivibrio species

bacteria 1. Scott KP , Barbosa TM , Forbes KJ , Flint HJ ( 1997 ) Appl Environ Microbiol 63 , 3405 - 34111

Development of a multi-locus sequence typing scheme for Laribacter hongkongensis, a novel bacterium associated with freshwater fish-borne gastroenteritis and traveler's diarrhea

Background Laribacter hongkongensis is a newly discovered, facultative anaerobic, Gram-negative, motile, sea gull-shaped rod associated with freshwater fish borne gastroenteritis and traveler's diarrhea. A highly reproducible and discriminative typing system is essential for better understanding of the epidemiology of L. hongkongensis. In this study, a multilocus sequence typing...

Radiological analysis of children with cystic fibrosis who are homozygous for cystic fibrosis transmembrane conductance regulator mutation S549R (T→G)

Biol Clin 1996 ; 54 : 235 ± 41 . 9. Stern RC . The diagnosis of cystic ®brosis . New Engl J Med 1997 ; 336 : 487 ± 91 . 10. Dawson KP , Frossard PM . Cystic ®brosis in the United Arab Emirates: an under ... -recognised condition? Tropical Doctor 1995 ; 25 : 110 ± 11 . 11. Frossard PM , Girodon E , Dawson KP , et al. Identi®cation of cystic ®brosis mutations in the United Arab Emirates . Hum Mut 1997 ; Mutation in

Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells

Background Thalidomide is an immunomodulatory agent, which arrests angiogenesis. The mechanism of anti-angiogenic activity of thalidomide is not fully understood. As nitric oxide is involved in angiogenesis, we speculate a cross-talk between thalidomide and nitric oxide signaling pathway to define angiogenesis. The aim of present study is to understand the mechanistic aspects of...

Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome

Background A modest change in HIV-1 fitness can have a significant impact on viral quasispecies evolution and viral pathogenesis, transmission and disease progression. To determine the impact of immune escape mutations selected by cytotoxic T lymphocytes (CTL) on viral fitness in the context of the cognate transmitted/founder (T/F) genome, we developed a new competitive fitness...

The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres

Background In the periphery, C5a acts through the G-protein coupled receptor CD88 to enhance/maintain inflammatory responses. In the brain, CD88 can be expressed on astrocytes, microglia and neurons. Previous studies have shown that the hippocampal CA3 region displays CD88-immunolabelling, and CD88 mRNA is present within dentate gyrus granule cells. As granule cells send dense...

Altered Neocortical Cell Density and Layer Thickness in Serotonin Transporter Knockout Mice: A Quantitation Study

, Wichems CH , Feltner D , Heils A , Moessner R , Westphal H , Lesch KP . 1998 . Altered brain serotonin homeostasis and locomotor insensitivity to 3,4-methylenedioxymethamphetamine (''Ecstasy'') in serotonin ... . Program No. 481.15 , 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience [online]. Canli T , Omura K , Haas BW , Fallgatter A , Constable RT , Lesch KP . 2005 . Beyond affect: a

Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells

transgenic mitochondrial cybrids generate Lewy inclusion bodies . J Neurochem 2004 , 88 : 800 - 812 . 21. Borland MK , Mohanakumar KP , Rubinstein JD , Keeney PM , Xie J , Capaldi R , Dunham LD , Trimmer PA

Case report. Intracranial haemorrhage due to vitamin K deficiency following gastroenteritis in an infant

Breastfed infants who are not given supplemental vitamin K after birth may develop vitamin K deficiency following gastroenteritis. Severe intracranial haemorrhage may occur.