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Downregulation and DNA methylation of ECRG4 in gastric cancer

Downregulation and DNA methylation of ECRG4 in gastric cancer Peng Deng,1 Xiao-Jing Chang,1 Zi-Ming Gao,2 Xiao-Yang Xu,1 An-Qi Sun,2 Kai Li,2 Dong-Qiu Dai1 1Department of Gastrointestinal Surgery and

Codesigned Wideband High-Efficiency Filtering SIW Slot Antenna with High Selectivity and Flat Gain Response

Copyright © 2018 Peng Kai Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

Current Status and Study Progress of Recombinant Human Endostatin in Cancer Treatment

published. Disclosures. Kai Li, Mingliang Shi and Shukui Qin have nothing to disclose. Compliance with Ethics Guidelines. This article is based on previously conducted studies and does not involve any new

Web of Science use in published research and review papers 1997–2017: a selective, dynamic, cross-domain, content-based analysis

Clarivate Analytics’s Web of Science (WoS) is the world’s leading scientific citation search and analytical information platform. It is used as both a research tool supporting a broad array of scientific tasks across diverse knowledge domains as well as a dataset for large-scale data-intensive studies. WoS has been used in thousands of published academic studies over the past 20...

Autophagy is required for human umbilical cord mesenchymal stem cells to improve spatial working memory in APP/PS1 transgenic mouse model

Background Recent studies have shown that autophagy plays a central role in mesenchymal stem cells (MSCs), and many studies have shown that human umbilical cord MSCs (huMSCs) can treat Alzheimer’s disease (AD) through a variety of mechanisms. However, no studies have looked at the effects of autophagy on neuroprotective function of huMSCs in the AD mouse model. Thus, in this...

Sealing Performance and Optimization of a Subsea Pipeline Mechanical Connector

research interests are mechanical design and reliability design. Shao‑Kai Li born in 1990, is currently a master candidate at College of Mechanical and Electrical Engineering, Harbin Engineering University

Clinical value of ALU concentration and integrity index for the early diagnosis of ovarian cancer: A retrospective cohort trial

Conceptualization: Chungen Xing, Kai Li. Data curation: Rong Zhang, Wangyang PU, Shuyun Zhang, Li Chen, Weipei Zhu. Formal analysis: Rong Zhang, Wangyang PU, Shuyun Zhang, Li Chen, Weipei Zhu, Li Xiao, Funding ... acquisition: Rong Zhang, Chungen Xing. Investigation: Rong Zhang, Shuyun Zhang, Li Chen, Weipei Zhu. Methodology: Rong Zhang, Wangyang PU, Li Xiao, Kai Li. Resources: Shuyun Zhang, Li Chen, Weipei Zhu

Hsa_circ_0001859 Regulates ATF2 Expression by Functioning as an MiR-204/211 Sponge in Human Rheumatoid Arthritis

Background. circRNAs are part of the competitive endogenous RNA network, which putatively function as miRNA sponges and play a crucial role in the development of numerous diseases. However, studies of circRNAs in rheumatoid arthritis (RA) disease are limited. This work aims to identify the expression pattern of circRNAs in synovial tissues and their inflammatory regulation...

MiR-137 inhibited cell proliferation and migration of vascular smooth muscle cells via targeting IGFBP-5 and modulating the mTOR/STAT3 signaling

migration. The present study advances our knowledge into understanding the molecular mechanisms underlying the miR-137-regulated VSMCs proliferation. Author Contributions Conceptualization: Jin Pan, Kai Li ... . Data curation: Kai Li, Wei Huang. Formal analysis: Kai Li, Xiaoqing Zhang. Funding acquisition: Jin Pan. Investigation: Kai Li, Wei Huang. Methodology: Wei Huang. Project administration: Wei Huang

Association between elevated central venous pressure and outcomes in critically ill patients

Background Some prior studies have shown that elevated mean central venous pressure in certain patient populations and disease processes may lead to poor prognosis. However, these studies failed to generalize the concept of elevated central venous pressure (ECVP) load to all patients in critical care settings because of the limited cases and exclusive cohorts. The aim of the...

Game Equilibrium of False Information Diffusion in Public Crisis on Interpersonal Network

ITM Web of Conferences Game Equilibrium of False Information Crisis on Interpersonal Network Diffusion in Public Kai LI 1 Jia-Jia HAO 0 0 School of Economics and management Yanshan University

Game Equilibrium of False Information Diffusion in Public Crisis on Interpersonal Network

ITM Web of Conferences Game Equilibrium of False Information Crisis on Interpersonal Network Diffusion in Public Kai LI 1 Jia-Jia HAO 0 0 School of Economics and management Yanshan University

Preparation, Pharmacokinetic Profile, and Tissue Distribution Studies of a Liposome-Based Formulation of SN-38 Using an UPLC–MS/MS Method

The application of 7-ethyl-10-hydroxycamptothecin (SN-38) in cancer treatment is limited by its low solubility. This study is to develop a liposome-entrapped formulation of SN-38 (LE-SN38) to solve the obstacle and to evaluate its pharmacokinetic profile in dogs and tissue distribution in mice. LE-SN38 which is more likely to be suitable for large-scale production was prepared by...

Decreased FOXP3+ and GARP+ Tregs to neoadjuvant chemotherapy associated with favorable prognosis in advanced gastric cancer

Decreased FOXP3+ and GARP+ Tregs to neoadjuvant chemotherapy associated with favorable prognosis in advanced gastric cancer Kai Li,1 Fuchao Chen,2 Huijuan Xie3 1Department of Pathology, 2Department

Evaluation of the ablation margin of hepatocellular carcinoma using CEUS-CT/MR image fusion in a phantom model and in patients

Background To assess the accuracy of contrast-enhanced ultrasound (CEUS)-CT/MR image fusion in evaluating the radiofrequency ablative margin (AM) of hepatocellular carcinoma (HCC) based on a custom-made phantom model and in HCC patients. Methods Twenty-four phantoms were randomly divided into a complete ablation group (n = 6) and an incomplete ablation group (n = 18). After...

Shakedown modeling of unsaturated expansive soils subjected to wetting and drying cycles

It is important to model the behavior of unsaturated expansive soils subjected to wetting and drying cycles because they alter significantly their hydro-mechanical behavior and therefore cause a huge differential settlement on shallow foundations of the structure. A simplified model based on the shakedown theory (Zarka method) has been developed in this study for unsaturated...

De Novo Assembly and Developmental Transcriptome Analysis of the Small White Butterfly Pieris rapae

The small white butterfly Pieris rapae is one of the most destructive pests of Brassicaceae. Yet little is understood about its genes involved in development. To facilitate research on P. rapae, we sequenced the transcriptome of P. rapae during six developmental stages, including the egg, three larval stages, the pupa, and the adult. In total, 240 million high-quality reads were...

Minimally invasive percutaneous nephrolithotomy improves stone-free rates for impacted proximal ureteral stones: A systematic review and meta-analysis

Background Urinary stones are common medical disorders and the treatment of impacted proximal ureteral stones (IPUS) is still a challenge for urologists. The aim of this study was to compare the efficacy and safety of minimally invasive percutaneous nephrolithotomy (MI-PCNL) and ureteroscopic lithotripsy (URL) in the treatment of IPUS via a meta-analysis. Methods We collected...