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Search: authors:"Kaijin Wu"

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Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation

There is currently no FDA approved therapeutic agent for ARS mitigation post radiation exposure. Here we report that the small molecule YH250, which specifically antagonizes p300/catenin interaction, stimulates hematopoiesis in lethally or sublethally irradiated mice. A single administration of YH250 24 hours post irradiation can significantly stimulate HSC proliferation, improve...

The Effects of Apolipoprotein F Deficiency on High Density Lipoprotein Cholesterol Metabolism in Mice

developed by chemiluminescene using the ECL reagent from GE, and allowed to expose film. The rabbit anti-mouse apo F antibody was a kind gift from Dr. Kaijin Wu and Dr. Sarah Hamm-Alvarez (University of