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Search: authors:"Kaitao Zhao"

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RNA binding protein 24 regulates the translation and replication of hepatitis C virus

, RNA immunoprecipitation; RPA, RNase protection assay; RRM, RNA recognition motif; UTR, untranslated region. COMPLIANCE WITH ETHICS GUIDELINES Huang Cao, Kaitao Zhao, Yongxuan Yao, Jing Guo, Xiaoxiao

Productive HBV infection of well-differentiated, hNTCP-expressing human hepatoma-derived (Huh7) cells

Feasible and effective cell models for hepatitis B virus (HBV) infection are required for investigating the complete lifecycle of this virus, including the early steps of viral entry. Resistance to dimethyl sulfoxide/polyethylene glycol (DMSO/PEG), hNTCP expression, and a differentiated state are the limiting factors for successful HBV infection models. In the present study, we...

MITA/STING and Its Alternative Splicing Isoform MRP Restrict Hepatitis B Virus Replication

An efficient clearance of hepatitis B virus (HBV) requires the coordinated work of both the innate and adaptive immune responses. MITA/STING, an adapter protein of the innate immune signaling pathways, plays a key role in regulating innate and adaptive immune responses to DNA virus infection. Previously, we identified an alternatively spliced isoform of MITA/STING, called MITA...