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Search: authors:"Karin van Veldhoven"

4 papers found.
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Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis

Background Interest in the potential of DNA methylation in peripheral blood as a biomarker of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation measured in peripheral blood samples obtained before onset of the disease is associated with increased risk of breast cancer. We report on three independent prospective nested case-control studies from...

Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation

Remarkable progress in the field of epigenetics has turned academic, medical and public attention to the potential applications of these new advances in medicine and various fields of biomedical research. The result is a broader appreciation of epigenetic phenomena in the a etiology of common human diseases, most notably cancer. These advances also represent an exciting...

Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking

A single cytosine–guanine dinucleotide (CpG) site within coagulation factor II (thrombin) receptor-like 3 (F2RL3) was recently found to be hypomethylated in peripheral blood genomic DNA from smokers compared with former and non-smokers. We performed two epigenome-wide association studies (EWAS) nested in a prospective healthy cohort using the Illumina 450K Methylation Beadchip...

Methylome Analysis and Epigenetic Changes Associated with Menarcheal Age

with Menarcheal Age Christiana A. Demetriou Jia Chen Silvia Polidoro Karin van Veldhoven Cyrille Cuenin Gianluca Campanella Kevin Brennan Fran coise Clavel-Chapelon Laure Dossus Marina Kvaskoff Dagmar