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Search: authors:"Karl Nordström"

8 papers found.
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Constraining new resonant physics with top spin polarisation information

We provide a comprehensive analysis of the power of including top quark-polarisation information to kinematically challenging top pair resonance searches, for which ATLAS and CMS start losing sensitivity. Following the general modelling and analysis strategies pursued by the experiments, we analyse the semi-leptonic and the di-lepton channels and show that including polarisation ...

Mapping monojet constraints onto simplified dark matter models

The move towards simplified models for Run II of the LHC will allow for stronger and more robust constraints on the dark sector. However there already exists a wealth of Run I data which should not be ignored in the run-up to Run II. Here we reinterpret public constraints on generic beyond-standard-model cross sections to place new constraints on a simplified model. We make use of ...

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction

The binding and contribution of transcription factors (TF) to cell specific gene expression is often deduced from open-chromatin measurements to avoid costly TF ChIP-seq assays. Thus, it is important to develop computational methods for accurate TF binding prediction in open-chromatin regions (OCRs). Here, we report a novel segmentation-based method, TEPIC, to predict TF binding by ...

Epigenetic dynamics of monocyte-to-macrophage differentiation

Thomas Lengauer 6 Matthias Barann 5 Philip Rosenstiel 5 Gilles Gasparoni 10 Karl Nordström 10 Jörn Walter 10 Benedikt Brors 9 Gideon Zipprich 9 Bärbel Felder 9 Ludger Klein‑Hitpass 3 Corinna Attenberger 11

LHAPDF6: parton density access in the LHC precision era

The Fortran LHAPDF library has been a long-term workhorse in particle physics, providing standardised access to parton density functions for experimental and phenomenological purposes alike, following on from the venerable PDFLIB package. During Run 1 of the LHC, however, several fundamental limitations in LHAPDF’s design have became deeply problematic, restricting the usability of ...

A general concept for consistent documentation of computational analyses

The ever-growing amount of data in the field of life sciences demands standardized ways of high-throughput computational analysis. This standardization requires a thorough documentation of each step in the computational analysis to enable researchers to understand and reproduce the results. However, due to the heterogeneity in software setups and the high rate of change during tool ...

Human Cytomegalovirus Drives Epigenetic Imprinting of the IFNG Locus in NKG2Chi Natural Killer Cells

Memory type 1 T helper (TH1) cells are characterized by the stable expression of interferon (IFN)-γ as well as by the epigenetic imprinting of the IFNG locus. Among innate cells, NK cells play a crucial role in the defense against cytomegalovirus (CMV) and represent the main source of IFN-γ. Recently, it was shown that memory-like features can be observed in NK cell subsets after ...